Cytoplasmic tail motifs mediate endoplasmic reticulum localization and export of transmembrane reporters in the protozoan parasite Toxoplasma gondii

Toxoplasmosis of Animals and Man

1989 • 1,765 citations

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER

1989 • 1,685 citations

Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum.

1990 • 918 citations

Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic

1991 • 832 citations

Chapter 3: Molecular Tools for Genetic Dissection of the Protozoan Parasite Toxoplasma gondii

1995 • 592 citations

Coatomer Interaction with Di-Lysine Endoplasmic Reticulum Retention Motifs

1994 • 574 citations

SIGNAL-MEDIATED SORTING OF MEMBRANE PROTEINS BETWEEN THE ENDOPLASMIC RETICULUM AND THE GOLGI APPARATUS

1996 • 506 citations

GTP-binding mutants of rab1 and rab2 are potent inhibitors of vesicular transport from the endoplasmic reticulum to the Golgi complex.

1992 • 497 citations

A Di-Acidic Signal Required for Selective Export from the Endoplasmic Reticulum

1997 • 487 citations

Vesicular stomatitis virus glycoprotein is sorted and concentrated during export from the endoplasmic reticulum

1994 • 392 citations

Brefeldin A

1999 • 385 citations

Basolateral sorting of LDL receptor in MDCK cells: The cytoplasmic domain contains two tyrosine-dependent targeting determinants

1992 • 366 citations

Protein sorting by tyrosine-based signals: adapting to the Ys and wherefores

1997 • 329 citations

An N-terminal double-arginine motif maintains type II membrane proteins in the endoplasmic reticulum.

1994 • 315 citations

Golgi Structure Correlates with Transitional Endoplasmic Reticulum Organization in Pichia pastoris and Saccharomyces cerevisiae

1999 • 313 citations

Cargo Selection by the COPII Budding Machinery during Export from the ER

1998 • 284 citations

Invited review Apical organelles and host-cell invasion by Apicomplexa

1998 • 278 citations

The Recycling of ERGIC-53 in the Early Secretory Pathway

1997 • 272 citations

Altered cytoplasmic domains affect intracellular transport of the vesicular stomatitis virus glycoprotein

1983 • 264 citations

TGN38 is maintained in the trans-Golgi network by a tyrosine-containing motif in the cytoplasmic domain.

1993 • 231 citations

Efficient Export of the Vesicular Stomatitis Virus G Protein from the Endoplasmic Reticulum Requires a Signal in the Cytoplasmic Tail That Includes Both Tyrosine-based and Di-acidic Motifs

2000 • 179 citations

ERGIC-53 is a functional mannose-selective and calcium-dependent human homologue of leguminous lectins.

1996 • 177 citations

The nuclear envelope serves as an intermediary between the ER and Golgi complex in the intracellular parasite Toxoplasma gondii

1999 • 173 citations

Mistargeting of the Lectin ERGIC-53 to the Endoplasmic Reticulum of HeLa Cells Impairs the Secretion of a Lysosomal Enzyme

1998 • 162 citations

Transmembrane domain-dependent sorting of proteins to the ER and plasma membrane in yeast

1997 • 161 citations

The TGN38 glycoprotein contains two non-overlapping signals that mediate localization to the trans-Golgi network.

1994 • 134 citations

Cytoplasmic determinants involved in direct lysosomal sorting, endocytosis, and basolateral targeting of rat lgp120 (lamp-I) in MDCK cells.

1995 • 130 citations

Cloning and restriction mapping of the alkaline phosphatase structural gene (phoA) of Escherichia coli and generation of deletion mutants in vitro

1981 • 126 citations

The Transmembrane Domain of a Carboxyl-terminal Anchored Protein Determines Localization to the Endoplasmic Reticulum

1997 • 122 citations

Targeting to rhoptry organelles of Toxoplasma gondii involves evolutionarily conserved mechanisms.

2000 • 121 citations

The Protozoan Parasite Toxoplasma gondii Targets Proteins to Dense Granules and the Vacuolar Space Using Both Conserved and Unusual Mechanisms

1998 • 120 citations

Distinct compartmentalization of TGN46 and beta 1,4-galactosyltransferase in HeLa cells.

1997 • 116 citations

New COP1-binding motifs involved in ER retrieval

1998 • 81 citations

Does COPI Go Both Ways?

1997 • 81 citations

The role of coat proteins in the biosynthesis of secretory proteins

1995 • 73 citations

Differential sorting and post-secretory targeting of proteins in parasitic invasion

2000 • 69 citations

A tyrosine-containing motif mediates ER retention of CD3-epsilon and adopts a helix-turn structure.

1995 • 66 citations

Sorting Determinants in the Transmembrane Domain of p24 Proteins

1997 • 54 citations

Conformational analysis of neuropeptide Y-[18–36] analogs in hydrophobic environments

1997 • 43 citations

Advances in cell and molecular biology of membranes and organelles

1994 • 37 citations

Targeting the Secretory Pathway ofToxoplasma gondii

1997 • 24 citations

Molecular genetic strategies in Toxoplasma gondii: close in on a successful invader

1996 • 13 citations