Cytoplasmic determinants involved in direct lysosomal sorting, endocytosis, and basolateral targeting of rat lgp120 (lamp-I) in MDCK cells.

The Biogenesis of Lysosomes

1989 • 1,583 citations

Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors.

1979 • 1,301 citations

Lysosomal membrane glycoproteins. Structure, biosynthesis, and intracellular trafficking.

1991 • 552 citations

Basolateral sorting of LDL receptor in MDCK cells: The cytoplasmic domain contains two tyrosine-dependent targeting determinants

1992 • 366 citations

Specificity of binding of clathrin adaptors to signals on the mannose-6-phosphate/insulin-like growth factor II receptor.

1989 • 336 citations

Basolateral sorting in MDCK cells requires a distinct cytoplasmic domain determinant

1991 • 304 citations

An autonomous signal for basolateral sorting in the cytoplasmic domain of the polymeric immunoglobulin receptor

1991 • 298 citations

Plasma membrane protein sorting in polarized epithelial cells.

1992 • 272 citations

Accumulation of membrane glycoproteins in lysosomes requires a tyrosine residue at a particular position in the cytoplasmic tail.

1990 • 272 citations

A single amino acid change in the cytoplasmic domain alters the polarized delivery of influenza virus hemagglutinin.

1991 • 257 citations

A di-leucine motif mediates endocytosis and basolateral sorting of macrophage IgG Fc receptors in MDCK cells.

1994 • 253 citations

Transport of the lysosomal membrane glycoprotein lgp120 (lgp-A) to lysosomes does not require appearance on the plasma membrane

1992 • 252 citations

Cycling of the integral membrane glycoprotein, LEP100, between plasma membrane and lysosomes: Kinetic and morphological analysis

1987 • 244 citations

A His-Leu-Leu sequence near the carboxyl terminus of the cytoplasmic domain of the cation-dependent mannose 6-phosphate receptor is necessary for the lysosomal enzyme sorting function.

1992 • 205 citations

Kinetics of intracellular transport and sorting of lysosomal membrane and plasma membrane proteins.

1987 • 197 citations

Lysosomal acid phosphatase is transported to lysosomes via the cell surface.

1989 • 189 citations

Internalization and rapid recycling of macrophage Fc receptors tagged with monovalent antireceptor antibody: possible role of a prelysosomal compartment.

1984 • 176 citations

The motif Tyr-X-X-hydrophobic residue mediates lysosomal membrane targeting of lysosome-associated membrane protein 1.

1993 • 169 citations

Common signals control low density lipoprotein receptor sorting in endosomes and the Golgi complex of MDCK cells

1993 • 167 citations

The essential tyrosine of the internalization signal in lysosomal acid phosphatase is part of a β turn

1991 • 165 citations

Purification and characterization of human lysosomal membrane glycoproteins

1989 • 163 citations

Vesicular stomatitis virus glycoprotein contains a dominant cytoplasmic basolateral sorting signal critically dependent upon a tyrosine.

1993 • 160 citations

Differential microtubule requirements for transcytosis in MDCK cells.

1990 • 159 citations

An internal deletion in the cytoplasmic tail reverses the apical localization of human NGF receptor in transfected MDCK cells.

1991 • 153 citations

Expression of macrophage-lymphocyte Fc receptors in Madin-Darby canine kidney cells: polarity and transcytosis differ for isoforms with or without coated pit localization domains.

1989 • 143 citations

Mutational and secondary structural analysis of the basolateral sorting signal of the polymeric immunoglobulin receptor.

1993 • 140 citations

The basolateral targeting signal in the cytoplasmic domain of glycoprotein G from vesicular stomatitis virus resembles a variety of intracellular targeting motifs related by primary sequence but having diverse targeting activities.

1994 • 127 citations

The residues Leu(Ile)475-Ile(Leu, Val, Ala)476, contained in the extended carboxyl cytoplasmic tail, are critical for targeting of the resident lysosomal membrane protein LIMP II to lysosomes.

1994 • 126 citations

An endogenous MDCK lysosomal membrane glycoprotein is targeted basolaterally before delivery to lysosomes.

1991 • 117 citations

The cytoplasmic tail of lysosomal acid phosphatase contains overlapping but distinct signals for basolateral sorting and rapid internalization in polarized MDCK cells.

1993 • 108 citations

Lysosomal targeting of Limp II membrane glycoprotein requires a novel Leu-Ile motif at a particular position in its cytoplasmic tail.

1994 • 104 citations

The cytoplasmic domain of the polymeric immunoglobulin receptor contains two internalization signals that are distinct from its basolateral sorting signal.

1992 • 90 citations

The lysosomal membrane glycoprotein lamp-1 is transported to lysosomes by two alternative pathways

1992 • 83 citations

Cytoplasmic sequence required for basolateral targeting of LDL receptor in livers of transgenic mice

1992 • 82 citations

Related signals for endocytosis and basolateral sorting of the asialoglycoprotein receptor.

1993 • 82 citations

Targeting of lysosomal integral membrane protein LIMP II. The tyrosine-lacking carboxyl cytoplasmic tail of LIMP II is sufficient for direct targeting to lysosomes.

1991 • 63 citations

The pathway and targeting signal for delivery of the integral membrane glycoprotein LEP100 to lysosomes.

1992 • 61 citations

A kinetic analysis of biosynthesis and localization of a lysosome-associated membrane glycoprotein

1986 • 61 citations

The structure of an endocytosis signal

1992 • 56 citations

The internalization signal and the phosphorylation site of transferrin receptor are distinct from the main basolateral sorting information.

1993 • 55 citations

Morphological Localization of a Major Lysosomal Membrane Glycoprotein in the Endocytic Membrane System

1989 • 48 citations

Polarity signals in epithelial cells

1993 • 46 citations

Biochemical Analysis of the Movement of a Major Lysosomal Membrane Glycoprotein in the Endocytic Membrane System

1989 • 36 citations

Association of the precursor of cathepsin D with coated membranes. Kinetics and carbohydrate processing

1987 • 20 citations

Relationships between sorting in the exocytic and endocytic pathways of MDCK cells.

1991 • 18 citations