Werner protein recruits DNA polymerase δ to the nucleolus

Multiple Pathways of Recombination Induced by Double-Strand Breaks in Saccharomyces cerevisiae

1999 • 2,095 citations

Positional Cloning of the Werner's Syndrome Gene

1996 • 1,696 citations

Nucleolar Arf sequesters Mdm2 and activates p53

1999 • 937 citations

Initiation of genetic recombination and recombination-dependent replication

2000 • 675 citations

The Werner syndrome protein is a DNA helicase

1997 • 597 citations

Telomerase-Mediated Telomere Addition In Vivo Requires DNA Primase and DNA Polymerases α and δ

1999 • 377 citations

Human Werner Syndrome DNA Helicase Unwinds Tetrahelical Structures of the Fragile X Syndrome Repeat Sequence d(CGG)

1999 • 362 citations

Mutations in Human ARF Exon 2 Disrupt Its Nucleolar Localization and Impair Its Ability to Block Nuclear Export of MDM2 and p53

1999 • 343 citations

Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts

2000 • 329 citations

Ku complex interacts with and stimulates the Werner protein

2000 • 308 citations

Bloom’s and Werner’s syndrome genes suppress hyperrecombination in yeast sgs1 mutant: Implication for genomic instability in human diseases

1998 • 298 citations

A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity

1998 • 295 citations

Cooperative Signals Governing ARF-Mdm2 Interaction and Nucleolar Localization of the Complex

2000 • 274 citations

Werner Syndrome Protein

1998 • 268 citations

The Werner Syndrome Gene Product Co-purifies with the DNA Replication Complex and Interacts with PCNA and Topoisomerase I

1999 • 249 citations

Nucleolar localization of the Werner syndrome protein in human cells

1998 • 210 citations

Impaired S-phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines

1992 • 207 citations

The nucleolus: the magician’s hat for cell cycle tricks

2000 • 195 citations

Eukaryotic DNA polymerases in DNA replication and DNA repair

1998 • 193 citations

Nuclear structure in normal and Bloom syndrome cells

2000 • 189 citations

Functional interaction between the Werner Syndrome protein and DNA polymerase δ

2000 • 187 citations

Structure and Processivity of Two Forms of Saccharomyces cerevisiae DNA Polymerase δ

1998 • 181 citations

Physical and Functional Interaction between p53 and the Werner's Syndrome Protein

1999 • 181 citations

p53-Mediated apoptosis is attenuated in Werner syndrome cells

1999 • 175 citations

Mutations in the consensus helicase domains of the Werner syndrome gene. Werner's Syndrome Collaborative Group.

1997 • 146 citations

Werner Helicase Is Localized to Transcriptionally Active Nucleoli of Cycling Cells

1998 • 141 citations

In vivo evidence that TATA-binding protein/SL1 colocalizes with UBF and RNA polymerase I when rRNA synthesis is either active or inactive.

1996 • 141 citations

DNA helicases in inherited human disorders

1997 • 140 citations

Replication focus-forming activity 1 and the Werner syndrome gene product

1998 • 139 citations

The DNA Helicase Activity of BLM Is Necessary for the Correction of the Genomic Instability of Bloom Syndrome Cells

1999 • 135 citations

An abnormal profile of DNA replication intermediates in Bloom's syndrome.

1990 • 107 citations

Identification of a Fourth Subunit of Mammalian DNA Polymerase δ

2000 • 101 citations

The fission yeast Cdc1 protein, a homologue of the small subunit of DNA polymerase delta, binds to Pol3 and Cdc27.

1996 • 100 citations

WRN helicase expression in Werner syndrome cell lines

2000 • 91 citations

Review

1997 • 86 citations

The small subunit is required for functional interaction of DNA polymerase delta with the proliferating cell nuclear antigen

1997 • 67 citations

Structure and Activity Associated with Multiple Forms ofSchizosaccharomyces pombe DNA Polymerase δ

2000 • 64 citations

Genetics and the pathobiology of ageing

1997 • 60 citations

WRN or telomerase constructs reverse 4-nitroquinoline 1-oxide sensitivity in transformed Werner syndrome fibroblasts.

2000 • 56 citations

Information for Authors

1997 • 43 citations

Delayed DNA maturation, a possible cause of the elevated sister-chromatid exchange in Bloom's syndrome

1986 • 37 citations

Decrease in the average size of replicons in a Werner syndrome cell line by Simian Virus 40 infection

1983 • 24 citations