Nucleolar localization of the Werner syndrome protein in human cells

Antibodies, a laboratory manual

1989 • 12,929 citations

Positional Cloning of the Werner's Syndrome Gene

1996 • 1,696 citations

Extrachromosomal rDNA Circles— A Cause of Aging in Yeast

1997 • 1,477 citations

The Bloom's syndrome gene product is homologous to RecQ helicases

1995 • 1,371 citations

A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the sam mRNA

1991 • 1,019 citations

Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype.

1970 • 1,002 citations

A Review of its Symptomatology, Natural History, Pathologic Features, Genetics And Relationship to the Natural Aging Process

1966 • 831 citations

The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase.

1994 • 686 citations

The Werner syndrome protein is a DNA helicase

1997 • 597 citations

Excess of rare cancers in Werner syndrome (adult progeria).

1996 • 435 citations

Mutator phenotype of Werner syndrome is characterized by extensive deletions.

1989 • 417 citations

Sgs1: A eukaryotic homolog of E. coil RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation

1995 • 402 citations

Accelerated Aging and Nucleolar Fragmentation in Yeast sgs1 Mutants

1997 • 399 citations

rqh1+, a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible S phase arrest

1997 • 354 citations

Silver staining, immunofluorescence, and immunoelectron microscopic localization of nucleolar phosphoproteins B23 and C23

1984 • 279 citations

Escherichia coli RecQ protein is a DNA helicase.

1990 • 263 citations

Werner's syndrome: A review of recent research with an analysis of connective tissue metabolism, growth control of cultured cells, and chromosomal aberrations

1982 • 254 citations

Cytogenetics of Werner’s syndrome cultured skin fibroblasts: variegated translocation mosaicism

1981 • 241 citations

Isolation and genetic characterization of a thymineless death-resistant mutant of Escherichia coli K12: Identification of a new mutation (recQ1) that blocks the RecF recombination pathway

1984 • 235 citations

Localization of nucleolar phosphoproteins B23 and C23 during mitosis

1983 • 230 citations

The Yeast Type I Topoisomerase Top3 Interacts with Sgsl, a DNA Helicase Homolog: a Potential Eukaryotic Reverse Gyrase

1994 • 209 citations

DNA helicase activity in Werner's syndrome gene product synthesized in a baculovirus system

1997 • 207 citations

Cloning and characterization of RECQL, a potential human homologue of the Escherichia coli DNA helicase RecQ.

1994 • 202 citations

Mutations in the consensus helicase domains of the Werner syndrome gene. Werner's Syndrome Collaborative Group.

1997 • 146 citations

Homozygous and compound heterozygous mutations at the Werner syndrome locus

1996 • 108 citations

Identification and characterization of a human proliferation-associated nucleolar antigen with a molecular weight of 120,000 expressed in early G1 phase.

1988 • 104 citations

Association of a polymorphic variant of the Werner helicase gene with myocardial infarction in a Japanese population

1997 • 102 citations

Increased frequency of 6-thioguanine-resistant peripheral blood lymphocytes in Werner syndrome patients

1990 • 87 citations

Loss of hybridizable ribosomal DNA from human post-mitotic tissues during aging: I. Age-dependent loss in human myocardium

1979 • 66 citations

Werner’s Syndrome and Human Aging

1985 • 61 citations

Localization of phosphoprotein C23 in nucleoli by immunological methods

1981 • 58 citations

Loss of hybridizable ribosomal DNA from human post-mitotic tissues during aging: II. Age-dependent loss in human cerebral cortex — Hippocampal and somatosensory cortex comparison

1979 • 52 citations

Down-Regulation of the Defective Transcripts of the Werner's Syndrome Gene in the Cells of Patients

1997 • 47 citations

Nucleolar changes in senescing WI-38 cells

1978 • 40 citations

Nucleocytoplasmic RNA transport

1985 • 37 citations

Constancy of ribosomal RNA genes during aging of mouse heart cells and during serial passage of WI-38 cells

1984 • 35 citations

Cloning of a Mouse Homologue of the Human Werner Syndrome Gene and Assignment to 8A4 by Fluorescencein SituHybridization

1997 • 29 citations

Epitope distribution and immunochemical characterization of nucleolar phosphoprotein C23 using ten monoclonal antibodies

1985 • 28 citations

Mapping nucleolar proteins with monoclonal antibodies.

1984 • 26 citations

Antibodies in cell biology

1994 • 12 citations

Molecular and epidemiological studies of Werner syndrome in the Japanese population

1997 • 8 citations

The effect of clinical and subclinical concentrations of lead on the in vitro aging of human fibroblasts

1983 • 7 citations

Culture media variation as related to in vitro aging of human fibroblasts: II. effects on nucleolar number/cell, volume/nucleolus and total nucleolar volume/cell

1988 • 6 citations