p34cdc2-mediated phosphorylation at T124 inhibits nuclear import of SV-40 T antigen proteins.

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Universal control mechanism regulating onset of M-phase

1990 • 2,882 citations

A short amino acid sequence able to specify nuclear location

1984 • 2,529 citations

NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control

1989 • 1,622 citations

Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal

1990 • 870 citations

The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA

1985 • 849 citations

A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo

1989 • 652 citations

Mutations of phosphorylation sites in lamin A that prevent nuclear lamina disassembly in mitosis

1990 • 642 citations

Identification and characterization of a nuclear pore complex protein

1986 • 610 citations

Nuclear protein localization

1991 • 570 citations

Construction and characterization of an SV40 mutant defective in nuclear transport of T antigen

1984 • 566 citations

A polypeptide domain that specifies migration of nucleoplasmin into the nucleus

1982 • 556 citations

How proteins enter the nucleus

1991 • 555 citations

Correlation between structure and mass distribution of the nuclear pore complex and of distinct pore complex components.

1990 • 510 citations

Substrates for p34cdc2: In vivo veritas?

1990 • 472 citations

The graded distribution of the dorsal morphogen is initiated by selective nuclear transport in Drosophila

1989 • 472 citations

Purified human IκB can rapidly dissociate the complex of the NF-κB transcription factor with its cognate DNA

1990 • 445 citations

The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells

1989 • 439 citations

Relocalization of the dorsal protein from the cytoplasm to the nucleus correlates with its function

1989 • 431 citations

A movable and regulable inactivation function within the steroid binding domain of the glucocorticoid receptor

1988 • 427 citations

The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization

1989 • 427 citations

Identification of cell cycle-regulated phosphorylation sites on nuclear lamin C

1990 • 425 citations

Sequence requirements for synthetic peptide-mediated translocation to the nucleus.

1989 • 413 citations

Driving the cell cycle: M phase kinase, its partners, and substrates

1990 • 404 citations

The fission yeast cdc2/cdc13/suc1 protein kinase: Regulation of catalytic activity and nuclear localization

1989 • 392 citations

In Vitro Activation and Nuclear Translocation of NF-κB Catalyzed by Cyclic AMP-Dependent Protein Kinase and Protein Kinase C

1989 • 389 citations

Targeting of E. coli β-galactosidase to the nucleus in yeast

1984 • 386 citations

Cell cycle control in eukaryotes: molecular mechanisms of cdc2 activation

1990 • 364 citations

Isolation of phosphorylated peptides and proteins on ion exchange papers

1978 • 359 citations

Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2.

1990 • 353 citations

The rate of nuclear cytoplasmic protein transport is determined by the casein kinase II site flanking the nuclear localization sequence of the SV40 T-antigen.

1991 • 351 citations

Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase

1990 • 344 citations

Intermediate filament reorganization during mitosis is mediated by p34cdc2 phosphorylation of vimentin

1990 • 328 citations

Rapid and reversible translocation of the catalytic subunit of cAMP-dependent protein kinase type II from the Golgi complex to the nucleus.

1985 • 317 citations

Identification of the Human c-myc Protein Nuclear Translocation Signal

1988 • 299 citations

Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization.

1984 • 284 citations

NF-κB, KBF1, dorsal, and related matters

1990 • 267 citations

Fluorescence microphotolysis to measure nucleocytoplasmic transport and intracellular mobility

1986 • 251 citations

In vitro mutagenesis of a putative DNA binding domain of SV40 large-T

1984 • 248 citations

Phosphorylation of large tumour antigen by cdc2 stimulates SV40 DNA replication

1989 • 242 citations

Mitosis-specific phosphorylation of p60c-src by p34cdc2-associated protein kinase

1989 • 239 citations

Primary structure analysis of an integral membrane glycoprotein of the nuclear pore.

1989 • 228 citations

Identification of specific binding proteins for a nuclear location sequence

1989 • 219 citations

Mutations in the nuclear lamin proteins resulting in their aberrant assembly in the cytoplasm.

1988 • 217 citations

The identification of a second cell cycle control on the HO promoter in yeast: Cell cycle regulation of SWI5 nuclear entry

1990 • 215 citations

Protein import through the nuclear pore complex is a multistep process.

1989 • 208 citations

Molecular mobility and nucleocytoplasmic flux in hepatoma cells.

1986 • 193 citations

The replication functions of SV40 T antigen are regulated by phosphorylation

1990 • 180 citations

Nuclear localization of c-Fos, but not v-Fos proteins, is controlled by extracellular signals

1990 • 178 citations

Nuclear transport kinetics depend on phosphorylation-site-containing sequences flanking the karyophilic signal of the Simian virus 40 T-antigen.

1989 • 175 citations

Differential Phosphorylation of c-Abl in Cell Cycle Determined by cdc 2 Kinase and Phosphatase Activity

1990 • 157 citations

Activation of human CDC2 protein as a histone H1 kinase is associated with complex formation with the p62 subunit.

1989 • 148 citations

Nuclear location signal-mediated protein transport

1989 • 144 citations

Primary sequence and heterologous expression of nuclear pore glycoprotein p62.

1990 • 137 citations

The p53 nuclear localisation signal is structurally linked to a p34cdc2 kinase motif.

1990 • 135 citations

In Vitro phosphorylation of SV40 large T antigen

1988 • 103 citations

Yeast proteins that recognize nuclear localization sequences.

1989 • 99 citations

Antibodies to Asp-Asp-Glu-Asp Can Inhibit Transport of Nuclear Proteins into the Nucleus

1988 • 84 citations

The plasma-membrane-associated form of SV40 large tumor antigen: biochemical and biological properties

1986 • 83 citations

Identification and characterization of a nuclear localization sequence-binding protein in yeast.

1989 • 70 citations

Differential ability of a T-antigen transport-defective mutant of simian virus 40 to transform primary and established rodent cells.

1985 • 69 citations

Identification of a human protein that interacts with nuclear localization signals.

1989 • 62 citations

Interaction of a nuclear location signal with isolated nuclear envelopes and identification of signal-binding proteins by photoaffinity labeling.

1989 • 44 citations

Differential phosphorylation of cytoplasmic and nuclear variants of simian virus 40 large T antigen encoded by simian virus 40-adenovirus 7 hybrid viruses

1984 • 41 citations

Differential Ability of a T-Antigen Transport-Defective Mutant of Simian Virus 40 To Transform Primary and Established Rodent Cells

1985 • 28 citations

Nucleocytoplasmic protein traffic in single mammalian cells studied by fluorescence microphotolysis

1987 • 25 citations

Tumorigenesis in transgenic mice by a nuclear transport-defective SV40 large T-antigen gene

1987 • 20 citations

Characterization of two mutants of the LLC-PK1 porcine kidney cell line affected in the catalytic subunit of the cAMP-dependent protein kinase

1987 • 19 citations

Mechanisms of cAMP-mediated gene induction: Examination of renal epithelial cell mutants affected in the catalytic subunit of the cAMP-dependent protein kinase

1991 • 15 citations

Only a minor fraction of plasma membrane-associated large T antigen in simian virus 40-transformed mouse tumor cells (mKSA) is exposed on the cell surface

1989 • 8 citations

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