Intermediate filament reorganization during mitosis is mediated by p34cdc2 phosphorylation of vimentin

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Silver staining of proteins in polyacrylamide gels

1981 • 3,565 citations

Universal control mechanism regulating onset of M-phase

1990 • 2,882 citations

MOLECULAR AND CELLULAR BIOLOGY OF INTERMEDIATE FILAMENTS

1988 • 1,395 citations

The nuclear envelope lamina is reversibly depolymerized during mitosis

1980 • 956 citations

Isolation of a human cyclin cDNA: Evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2

1989 • 920 citations

Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+

1988 • 885 citations

The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis

1988 • 829 citations

Activation of cdc2 protein kinase during mitosis in human cells: Cell cycle-dependent phosphorylation and subunit rearrangement

1988 • 786 citations

In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase

1990 • 783 citations

Cyclin is a component of maturation-promoting factor from Xenopus

1990 • 674 citations

cdc2 protein kinase is complexed with both cyclin A and B: Evidence for proteolytic inactivation of MPF

1989 • 666 citations

Mutations of phosphorylation sites in lamin A that prevent nuclear lamina disassembly in mitosis

1990 • 642 citations

MPF from starfish oocytes at first meiotic metaphase is a heterodimer containing one molecule of cdc2 and one molecule of cyclin B.

1989 • 550 citations

cdc2 is a component of the M phase-specific histone H1 kinase: Evidence for identity with MPF

1988 • 535 citations

Identification of cell cycle-regulated phosphorylation sites on nuclear lamin C

1990 • 425 citations

The fission yeast cdc2/cdc13/suc1 protein kinase: Regulation of catalytic activity and nuclear localization

1989 • 392 citations

p13suc1 acts in the fission yeast cell division cycle as a component of the p34cdc2 protein kinase.

1987 • 387 citations

p34cdc2 is located in both nucleus and cytoplasm; part is centrosomally associated at G2/M and enters vesicles at anaphase.

1989 • 376 citations

Phosphorylation of the nuclear lamins during interphase and mitosis.

1985 • 354 citations

Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2.

1990 • 353 citations

Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase

1990 • 344 citations

Purified maturation promoting factor phosphorylates pp60c-src at the sites phosphorylated during fibroblast mitosis

1989 • 319 citations

Activation at M-phase of a protein kinase encoded by a starfish homologue of the cell cycle control gene cdc2+

1988 • 314 citations

Cyclin is a component of the sea urchin egg M-phase specific histone H1 kinase.

1989 • 308 citations

Functions of Cytoplasmic Fibers in Non-Muscle Cell Motility

1973 • 285 citations

Mammalian growth-associated H1 histone kinase: a homolog of cdc2+/CDC28 protein kinases controlling mitotic entry in yeast and frog cells.

1989 • 265 citations

Induction of early mitotic events in a cell-free system

1985 • 263 citations

A 60 kd cdc2-associated polypeptide complexes with the E1A proteins in adenovirus-infected cells

1989 • 262 citations

The role of cyclin B in meiosis I.

1989 • 241 citations

Mitosis-specific phosphorylation of p60c-src by p34cdc2-associated protein kinase

1989 • 239 citations

Molecular cloning and characterization of the mRNA for cyclin from sea urchin eggs.

1987 • 220 citations

Disruption of the in vivo distribution of the intermediate filaments in fibroblasts through the microinjection of a specific monoclonal antibody

1981 • 170 citations

Phosphorylation and disassembly of intermediate filaments in mitotic cells.

1989 • 167 citations

An alteration in the phosphorylation of vimentin-type intermediate filaments is associated with mitosis in cultured mammalian cells

1982 • 158 citations

Domain- and sequence-specific phosphorylation of vimentin induces disassembly of the filament structure

1989 • 158 citations

Differential Phosphorylation of c-Abl in Cell Cycle Determined by cdc 2 Kinase and Phosphatase Activity

1990 • 157 citations

Involvement of the n-terminal polypeptide of vimentin in the formation of intermediate filaments

1983 • 153 citations

In vitro assembly of intermediate filaments from baby hamster kidney (BHK-21) cells.

1979 • 151 citations

Activation of human CDC2 protein as a histone H1 kinase is associated with complex formation with the p62 subunit.

1989 • 148 citations

Intermediate filaments of the vimentin-type and the cytokeratin-type are distributed differently during mitosis

1980 • 145 citations

Phosphorylation of keratin and vimentin polypeptides in normal and transformed mitotic human epithelial amnion cells: behavior of keratin and vimentin filaments during mitosis.

1983 • 141 citations

Phosphorylation of intermediate filament proteins by cAMP-dependent protein kinases

1981 • 128 citations

Mitotic control by metaphase-promoting factor and Cdc proteins

1989 • 126 citations

Dynamic aspects of intermediate filament networks in BHK-21 cells.

1989 • 125 citations

The fates of chicken nuclear lamin proteins during mitosis: evidence for a reversible redistribution of lamin B2 between inner nuclear membrane and elements of the endoplasmic reticulum.

1988 • 110 citations

Phosphorylation in vitro of vimentin by protein kinases A and C is restricted to the head domain

1989 • 99 citations

Isolation and partial characterization of a cage of filaments that surrounds the mammalian mitotic spindle.

1980 • 81 citations

Phosphorylation of vimentin in mitotically selected cells. In vitro cyclic AMP-independent kinase and calcium-stimulated phosphatase activities.

1989 • 69 citations

The intermediate-filament proteins vimentin and desmin are phosphorylated in specific domains.

1988 • 68 citations

Transient change of organization of vimentin filaments during mitosis as demonstrated by a monoclonal antibody

1984 • 66 citations

Dynamic properties of intermediate filaments: Disassembly and reassembly during mitosis in baby hamster kidney cells

1990 • 66 citations

Meiotic breakdown of nuclear envelope in oocytes of Spisula solidissima involves phosphorylation and release of nuclear lamin

1988 • 41 citations

Amino acid sequence characterization of mammalian vimentin, the mesenchymal intermediate filament protein

1983 • 40 citations