Mechanisms of cAMP-mediated gene induction: Examination of renal epithelial cell mutants affected in the catalytic subunit of the cAMP-dependent protein kinase

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

1989 • 2,486 citations

PROTEIN SERINE/THREONINE KINASES

1987 • 1,457 citations

Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene

1987 • 1,364 citations

A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence

1989 • 914 citations

The origin and characteristics of a pig kidney cell strain, LLC-PK1

1976 • 604 citations

Purification and characterization of catalytic subunit of skeletal muscle adenosine 3':5'-monophosphate-dependent protein kinase.

1977 • 328 citations

Rapid and reversible translocation of the catalytic subunit of cAMP-dependent protein kinase type II from the Golgi complex to the nucleus.

1985 • 317 citations

Identification of a region in the human vasoactive intestinal polypeptide gene responsible for regulation by cyclic AMP.

1987 • 236 citations

Cyclic-AMP-dependent protein kinase type II is associated with the Golgi complex and with centrosomes

1985 • 234 citations

Hormonal regulation of plasminogen activator mRNA production in porcine kidney cells

1983 • 151 citations

The phosphoform of the regulatory subunit RII of cyclic AMP-dependent protein kinase possesses intrinsic topoisomerase activity

1985 • 103 citations

Induction and desensitization of plasminogen activator gene expression by tumor promoters.

1985 • 103 citations

Nuclear phosphoprotein kinases and the regulation of gene transcription

1977 • 95 citations

Calcitonin stimulates plasminogen activator in porcine renal tubular cells: LLC-PK1.

1981 • 86 citations

cAMP mediated proteolysis of the catalytic subunit of cAMP‐dependent protein kinase

1986 • 74 citations

Inhibition of protein synthesis in LLC-PK1 cells increases calcitonin-induced plasminogen-activator gene transcription and mRNA stability

1987 • 64 citations

Transcriptional regulation of a plasminogen activator gene by cyclic AMP in a homologous cell-free system. Involvement of cyclic AMP-dependent protein kinase in transcriptional control.

1988 • 51 citations

Characterization of two mutants of the LLC-PK1 porcine kidney cell line affected in the catalytic subunit of the cAMP-dependent protein kinase

1987 • 19 citations

LLC‐PK₁ cell mutants in cAMP metabolism respond normally to phorbol esters

1986 • 18 citations

Complementation between LLC‐PK₁ mutants affected in polypeptide hormone‐receptor function

1987 • 11 citations

Pathway of urokinase-type plasminogen activator induction in the T47D and LLC-PK1, cell lines

1987 • 9 citations