Protein import through the nuclear pore complex is a multistep process.

A short amino acid sequence able to specify nuclear location

1984 • 2,529 citations

Cryo-electron microscopy of vitrified specimens

1988 • 2,252 citations

Sequence requirements for nuclear location of simian virus 40 large-T antigen

1984 • 1,278 citations

Molecular structure determination by electron microscopy of unstained crystalline specimens

1975 • 1,142 citations

Nuclear envelope permeability

1975 • 808 citations

Identification and characterization of a nuclear pore complex protein

1986 • 610 citations

Functional Organization Of The Nuclear Envelope

1988 • 593 citations

A polypeptide domain that specifies migration of nucleoplasmin into the nucleus

1982 • 556 citations

Nuclear protein migration involves two steps: Rapid binding at the nuclear envelope followed by slower translocation through nuclear pores

1988 • 551 citations

Protein Import into the Cell Nucleus

1986 • 544 citations

Nuclear import can be separated into distinct steps in vitro: Nuclear pore binding and translocation

1988 • 535 citations

Monoclonal antibodies identify a group of nuclear pore complex glycoproteins.

1987 • 533 citations

Inhibition of in vitro nuclear transport by a lectin that binds to nuclear pores.

1987 • 510 citations

Movement of a karyophilic protein through the nuclear pores of oocytes.

1984 • 510 citations

Synthetic peptides as nuclear localization signals

1986 • 472 citations

Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine.

1987 • 428 citations

RNA TRANSPORT FROM NUCLEUS TO CYTOPLASM IN CHIRONOMUS SALIVARY GLANDS

1966 • 361 citations

THE NUCLEUS: STRUCTURE, FUNCTION, AND DYNAMICS

1987 • 333 citations

Nuclear pore complex contains a family of glycoproteins that includes p62: glycosylation through a previously unidentified cellular pathway.

1987 • 330 citations

A large particle associated with the perimeter of the nuclear pore complex.

1982 • 314 citations

Injected nuclei in frog oocytes: fate, enlargement, and chromatin dispersal

1976 • 305 citations

The nucleoplasmin nuclear location sequence is larger and more complex than that of SV-40 large T antigen.

1988 • 296 citations

Translocation of RNA-coated gold particles through the nuclear pores of oocytes.

1988 • 292 citations

SPIDER—A modular software system for electron image processing

1981 • 287 citations

The effects of variations in the number and sequence of targeting signals on nuclear uptake.

1988 • 273 citations

O-linked N-acetylglucosamine is attached to proteins of the nuclear pore. Evidence for cytoplasmic and nucleoplasmic glycoproteins.

1987 • 268 citations

Nucleoplasmin cDNA sequence reveals polyglutamic acid tracts and a cluster of sequences homologous to putative nuclear localization signals.

1987 • 263 citations

Fluorescence microphotolysis to measure nucleocytoplasmic transport and intracellular mobility

1986 • 251 citations

Structure, biochemistry, and functions of the nuclear envelope.

1974 • 237 citations

Assembly in vitro of nuclei active in nuclear protein transport: ATP is required for nucleoplasmin accumulation.

1986 • 235 citations

Reversible inhibition of protein import into the nucleus by wheat germ agglutinin injected into cultured cells

1987 • 233 citations

Identification of specific binding proteins for a nuclear location sequence

1989 • 219 citations

A monoclonal antibody against the nuclear pore complex inhibits nucleocytoplasmic transport of protein and RNA in vivo.

1988 • 206 citations

tRNA transport from the nucleus in a eukaryotic cell: carrier-mediated translocation process.

1983 • 202 citations

Amino acid sequences that determine the nuclear localization of yeast histone 2B.

1987 • 194 citations

Interactions and structure of the nuclear pore complex revealed by cryo-electron microscopy.

1989 • 193 citations

Nuclear transport kinetics depend on phosphorylation-site-containing sequences flanking the karyophilic signal of the Simian virus 40 T-antigen.

1989 • 175 citations

The crystal structure of wheat germ agglutinin at 2·2 Å resolution

1977 • 130 citations

tRNA nuclear transport: Defining the critical regions of human tRNAimet by point mutagenesis

1985 • 118 citations

The nuclear location signal

1985 • 92 citations

Amino Acid Sequences That Determine the Nuclear Localization of Yeast Histone 2B

1987 • 86 citations

Effect of basic and nonbasic amino acid substitutions on transport induced by simian virus 40 T-antigen synthetic peptide nuclear transport signals.

1988 • 83 citations

Molecular structure determination of crystalline specimens in frozen aqueous solutions

1984 • 80 citations

Nuclear ribonucleoprotein release and nucleoside triphosphatase activity are inhibited by antibodies directed against one nuclear matrix glycoprotein.

1983 • 69 citations

The nuclear envelope and the organization of the pore complexes

1988 • 56 citations

The Preparation of Colloidal Gold Probes and Their Use as Marker in Electron Microscopy

1986 • 48 citations

Effect of Basic and Nonbasic Amino Acid Substitutions on Transport Induced by Simian Virus 40 T-Antigen Synthetic Peptide Nuclear Transport Signals

1988 • 31 citations

Karyophilic peptides: Applications to the study of nuclear transport

1988 • 30 citations

A Structural Model for the Nuclear Pore Complex

1986 • 17 citations