Groucho-Mediated Transcriptional Repression Establishes Progenitor Cell Pattern and Neuronal Fate in the Ventral Neural Tube

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

1996 • 3,041 citations

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

1999 • 1,139 citations

A Homeodomain Protein Code Specifies Progenitor Cell Identity and Neuronal Fate in the Ventral Neural Tube

2000 • 1,077 citations

Pax6 Controls Progenitor Cell Identity and Neuronal Fate in Response to Graded Shh Signaling

1997 • 1,019 citations

Requirement for LIM Homeobox Gene Isl1 in Motor Neuron Generation Reveals a Motor Neuron– Dependent Step in Interneuron Differentiation

1996 • 774 citations

Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling

1999 • 773 citations

The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors

1998 • 679 citations

Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins

1994 • 560 citations

A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1.

1995 • 548 citations

neurogenins,a Novel Family ofatonal-Related bHLH Transcription Factors, Are Putative Mammalian Neuronal Determination Genes That Reveal Progenitor Cell Heterogeneity in the Developing CNS and PNS

1996 • 536 citations

Specification of neuronal fates in the ventral neural tube

2001 • 530 citations

LIM Homeodomain Factors Lhx3 and Lhx4 Assign Subtype Identities for Motor Neurons

1998 • 438 citations

Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors

1999 • 386 citations

Control of Interneuron Fate in the Developing Spinal Cord by the Progenitor Homeodomain Protein Dbx1

2001 • 370 citations

Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes.

1994 • 364 citations

A Sonic Hedgehog–Independent, Retinoid-Activated Pathway of Neurogenesis in the Ventral Spinal Cord

1999 • 363 citations

Specification of Motor Neuron Identity by the MNR2 Homeodomain Protein

1998 • 340 citations

Regulation of patched by sonic hedgehog in the developing neural tube.

1996 • 331 citations

The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP.

1992 • 325 citations

A conserved region of engrailed, shared among all en-, gsc-, Nk1-, Nk2- and msh-class homeoproteins, mediates active transcriptional repression in vivo

1996 • 280 citations

Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates

2000 • 258 citations

PRDI-BF1/Blimp-1 repression is mediated by corepressors of the Groucho family of proteins

1999 • 248 citations

Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family

2000 • 247 citations

Transcriptional Coregulators in Development

1999 • 242 citations

Groucho acts as a corepressor for a subset of negative regulators, including Hairy and Engrailed

1997 • 240 citations

Dorsoventral patterning in the Drosophila central nervous system: the intermediate neuroblasts defective homeobox gene specifies intermediate column identity

1998 • 219 citations

Mash1andneurogenin1Expression Patterns Define Complementary Domains of Neuroepithelium in the Developing CNS and Are Correlated with Regions Expressing Notch Ligands

1997 • 210 citations

mRNA Profiling of Rat Islet Tumors Reveals Nkx 6.1 as a β-Cell-specific Homeodomain Transcription Factor

1996 • 210 citations

Specification of Neurotransmitter Identity by Phox2 Proteins in Neural Crest Stem Cells

1999 • 167 citations

The Homeodomain Protein NK-3 Recruits Groucho and a Histone Deacetylase Complex to Repress Transcription

1999 • 156 citations

Control of anteroposterior and dorsoventral domains of Nkx-6.1 gene expression relative to other Nkx genes during vertebrate CNS development

1998 • 148 citations

Pax6 defines the di-mesencephalic boundary by repressing En1 and Pax2

2000 • 144 citations

Vertebrate bHLH Genes and the Determination of Neuronal Fates

1999 • 142 citations

A role for the Msx-1 homeodomain in transcriptional regulation: residues in the N-terminal arm mediate TATA binding protein interaction and transcriptional repression.

1996 • 141 citations

Cells’ Perception of Position in a Concentration Gradient

1998 • 107 citations

Intramolecular control of transcriptional activity by the NK2-specific domain in NK-2 homeodomain proteins

2000 • 102 citations

NKX2 gene expression in neuroectoderm but not in mesendodermally derived structures depends on sonic hedgehog in mouse embryos

2000 • 92 citations

Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development

1996 • 80 citations

Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein

1993 • 71 citations

Cloning and developmental expression of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex

1993 • 61 citations

The Homeodomain Transcription Factor NK-4 Acts as either a Transcriptional Activator or Repressor and Interacts with the p300 Coactivator and the Groucho Corepressor

1999 • 59 citations

β-Cell Differentiation Factor Nkx6.1 Contains Distinct DNA Binding Interference and Transcriptional Repression Domains

2000 • 58 citations

Grg3, a murineGroucho-related gene, is expressed in the developing nervous system and in mesenchyme-induced epithelial structures

1997 • 56 citations

Antagonizing Activity of Chick Grg4 against Tectum-Organizing Activity

2000 • 41 citations

Cloning and DNA‐binding properties of the rat pancreatic β‐cell‐specific factor Nkx6.1

1999 • 38 citations