Antagonizing Activity of Chick Grg4 against Tectum-Organizing Activity

A series of normal stages in the development of the chick embryo

1951 • 12,226 citations

Expression of engrailed proteins in arthropods, annelids, and chordates

1989 • 1,019 citations

Midbrain development induced by FGF8 in the chick embryo

1996 • 734 citations

Drosophila Tcf and Groucho interact to repress Wingless signalling activity

1998 • 722 citations

Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesisy

1998 • 693 citations

The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors

1998 • 679 citations

Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins

1994 • 560 citations

Regulation of LEF-1/TCF transcription factors by Wnt and other signals

1999 • 537 citations

Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum

1994 • 509 citations

Engrailed, Wnt and Pax genes regulate midbrain-hindbrain development

1996 • 440 citations

A role for Gbx2 in repression of Otx2 and positioning the mid/hindbrain organizer

1999 • 346 citations

The WRPW Motif of the Hairy-Related Basic Helix-Loop-Helix Repressor Proteins Acts as a 4-Amino-Acid Transcription Repression and Protein-Protein Interaction Domain

1996 • 344 citations

The caudal limit of Otx2 expression positions the isthmic organizer

1999 • 338 citations

Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain

1997 • 326 citations

Groucho proteins: transcriptional corepressors for specific subsets of DNA-binding transcription factors in vertebrates and invertebrates

1998 • 299 citations

Pax-6 Is First Expressed in a Region of Ectoderm Anterior to the Early Neural Plate: Implications for Stepwise Determination of the Lens

1994 • 292 citations

Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development

1996 • 291 citations

Groucho acts as a corepressor for a subset of negative regulators, including Hairy and Engrailed

1997 • 240 citations

A series of no isthmus (noi) alleles of the zebrafish pax2.1 gene reveals multiple signaling events in development of the midbrain-hindbrain boundary

1998 • 235 citations

The function of hairy-related bHLH repressor proteins in cell fate decisions

1998 • 218 citations

Role of Pax‐5 in the regulation of a mid‐hindbrain organizer’s activity

1999 • 208 citations

Sequential roles for Fgf4, En1 and Fgf8 in specification and regionalisation of the midbrain

1999 • 207 citations

Patterning of the Embryonic Avian Midbrain after Experimental Inversions: A Polarizing Activity from the Isthmus

1994 • 201 citations

A deduced gene product from the Drosophila neurogenic locus, Enhancer of split, shows homology to mammalian G-protein β subunit

1988 • 197 citations

her4, a zebrafish homologue of the Drosophila neurogenic gene E(spl), is a target of NOTCH signalling

1999 • 188 citations

Rostral optic tectum acquires caudal characteristics following ectopic Engrailed expression

1996 • 179 citations

Regulation of the neural crest cell fate by N-myc: promotion of ventral migration and neuronal differentiation

1997 • 165 citations

Interaction between Otx2 and Gbx2 defines the organizing center for the optic tectum

2000 • 158 citations

The molecular genetics of Enhancer of split, a gene required for embryonic neural development in Drosophila.

1988 • 147 citations

Engrailed defines the position of dorsal di-mesencephalic boundary by repressing diencephalic fate

1999 • 132 citations

Direct regulation of the Xenopus engrailed-2 promoter by the Wnt signaling pathway, and a molecular screen for Wnt-responsive genes, confirm a role for Wnt signaling during neural patterning in Xenopus

1999 • 129 citations

A Role for Gradient en Expression in Positional Specification on the Optic Tectum

1996 • 126 citations

Ectopic induction and reorganization of Wnt-1 expression in quail/chick chimeras

1994 • 120 citations

A Role for Groucho Tetramerization in Transcriptional Repression

1998 • 119 citations

Establishment of rostrocaudal polarity in tectal primordium: engrailed expression and subsequent tectal polarity

1991 • 115 citations

Pax2/5 and Pax6 subdivide the early neural tube into three domains

1999 • 100 citations

Requirement for the zebrafish mid-hindbrain boundary in midbrain polarisation, mapping and confinement of the retinotectal projection*

1999 • 98 citations

Pluripotentiality of the 2-day-old avian germinative neuroepithelium

1990 • 95 citations

Comparative analysis of Otx2, Gbx2, Pax2, Fgf8 and Wnt1 gene expressions during the formation of the chick midbrain/hindbrain domain

1999 • 93 citations

En-2 regulates the expression of the ligands for Eph type tyrosine kinases in chick embryonic tectum

1997 • 80 citations

Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development

1996 • 80 citations

Products of the grg (Groucho-related Gene) Family Can Dimerize through the Amino-terminal Q Domain

1996 • 79 citations

Groucho: making its Marx as a transcriptional co-repressor

1998 • 72 citations

Roles of Pax-2 in initiation of the chick tectal development

1999 • 70 citations

Plasticity and rigidity of differentiation of brain vesicles studied in quail-chick chimeras

1986 • 70 citations

Regeneration of isthmic tissue is the result of a specific and direct interaction between rhombomere 1 and midbrain

1999 • 64 citations

groucho and hedgehog regulate engrailed expression in the anterior compartment of the Drosophila wing

1995 • 59 citations

A rat homolog of the Drosophila enhancer of split (groucho) locus lacking WD-40 repeats.

1993 • 43 citations

Ectopic expression of lunatic Fringe leads to downregulation of Serrate‐1 in the developing chick neural tube; analysis using in ovo electroporation transfection technique

1998 • 39 citations

A chick wingless mutation causes abnormality in maintenance of Fgf8 expression in the wing apical ridge, resulting in loss of the dorsoventral boundary

1997 • 34 citations

A common ancestor of the mammalian transcription factors TCF‐1 and TCF‐1α/LEF‐1 expressed in chicken T cells

1992 • 29 citations

Crossregulation between En‐2 and Wnt‐1 in chick tectal development

1998 • 21 citations

Expression of en in the Prosencephalon Heterotopically Transplanted into the Mesencephalon

1992 • 18 citations