Effect of Pretransplant Preconditioning by Whole Body Hyperthermia on Islet Graft Survival

Mammalian stress response: cell physiology, structure/function of stress proteins, and implications for medicine and disease

1992 • 1,201 citations

Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues

1996 • 1,136 citations

Successful Islet Transplantation

2002 • 727 citations

Islet isolation assessment in man and large animals

1990 • 575 citations

Synthesis and degradation of heat shock proteins during development and decay of thermotolerance.

1982 • 433 citations

Morphological study of the mammalian stress response: characterization of changes in cytoplasmic organelles, cytoskeleton, and nucleoli, and appearance of intranuclear actin filaments in rat fibroblasts after heat-shock treatment.

1985 • 428 citations

Large scale isolation, growth, and function of porcine neonatal islet cells.

1996 • 358 citations

Isolated Human Islets Trigger an Instant Blood Mediated Inflammatory Reaction: Implications for Intraportal Islet Transplantation as a Treatment for Patients with Type 1 Diabetes

2000 • 335 citations

Response of Human Islets to Isolation Stress and the Effect of Antioxidant Treatment

2004 • 277 citations

Transplantation of allogeneic islets of Langerhans in the rat liver: effects of macrophage depletion on graft survival and microenvironment activation.

1998 • 244 citations

Cell Loss in Isolated Human Islets Occurs by Apoptosis

2000 • 237 citations

Structural and functional changes resulting from islet isolation lead to islet cell death

1999 • 201 citations

Intracellular Stress Signaling Pathways Activated During Human Islet Preparation and Following Acute Cytokine Exposure

2004 • 179 citations

Brain Death Significantly Reduces Isolated Pancreatic Islet Yields and Functionality In Vitro and In Vivo After Transplantation in Rats

2003 • 166 citations

Heat shock induces resistance in rat pancreatic islet cells against nitric oxide, oxygen radicals and streptozotocin toxicity in vitro.

1995 • 156 citations

ENDOTOXIN-MEDIATED DELAYED ISLET GRAFT FUNCTION IS ASSOCIATED WITH INCREASED INTRA-ISLET CYTOKINE PRODUCTION AND ISLET CELL APOPTOSIS1

2001 • 138 citations

Assessment of intracellular insulin content during all steps of human islet isolation procedure

1998 • 102 citations

Assessment of Intracellular Insulin Content during All Steps of Human Islet Isolation Procedure

1998 • 65 citations

Altered bcl-2 and bax Expression and Intracellular Ca2+ Signaling in Apoptosis of Pancreatic Cells and the Impairment of Glucose-Induced Insulin Secretion*

1998 • 55 citations

PROTECTIVE EFFECT OF HEAT PRECONDITIONING OF RAT LIVER GRAFT RESULTING IN IMPROVED TRANSPLANT SURVIVAL1

2001 • 54 citations

Successful Single Donor Islet Allotransplantation in the Streptozotocin Diabetes Rat Model

2002 • 47 citations

Heat-induced thermal tolerance and radiation resistance to apoptosis in human lymphocytes

1997 • 31 citations

Low Stress Response Enhances Vulnerability of Islet Cells in Diabetes-Prone BB Rats

1997 • 29 citations

Heat-shock treatment of mouse pancreatic islets results in a partial loss of islet cells but no remaining functional impairment among the surviving β cells

1988 • 20 citations

Pretransplant Induction of HSP-70 in Isolated Adult Pig Islets Decreases Early Islet Xenograft Survival

2000 • 16 citations

Hyperthermic Preconditioning Protects Pig Islet Grafts from Early Inflammation but Enhances Rejection in Immunocompetent Mice

2003 • 15 citations

Monitoring of Enzymatic Digestions on Porcine Pancreatic Tissue Using a Simple Histological Assay

1998 • 3 citations

Pretransplant heat loading on pancreatic graft reduces posttransplant ischemia-reperfusion injury

2002 • 2 citations