Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Free radicals, antioxidants, and human disease: curiosity, cause, or consequence?

1994 • 3,002 citations

Free radicals and diabetes

1988 • 1,127 citations

CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in pancreatic islets and other tissues in the mouse

1981 • 502 citations

The role of O2.− in the production of HO.: in vitro and in vivo

1994 • 421 citations

STUDIES IN OBESE‐HYPERGLYCEMIC MICE*

1965 • 373 citations

Determinants of the selective toxicity of alloxan to the pancreatic B cell.

1982 • 280 citations

Alloxan: history and mechanism of action

1988 • 261 citations

Superoxide dismutase, catalase and scavengers of hydroxyl radical protect against the toxic action of alloxan on pancreatic islet cells in vitro

1979 • 206 citations

Thiol-group reactivity, hydrophilicity and stability of alloxan, its reduction products and its N-methyl derivatives and a comparison with ninhydrin

1991 • 119 citations

Transgenic copper/zinc superoxide dismutase modulates susceptibility to type I diabetes.

1994 • 108 citations

Nucleotide sequences of cDNAs coding for rat manganese-containing superoxide dismutase

1987 • 104 citations

Isolation of human fibroblast catalase cDNA clones. Sequence of clones derived from spliced and unspliced mRNA.

1984 • 90 citations

cDNA and deduced amino acid sequence of rat copper-zinc-containing superoxide dismutase

1987 • 59 citations

Nucleotide sequence of a rat glutathione peroxidase cDNA

1988 • 58 citations

The relationship between the physicochemical properties and the biological effects of alloxan and several N-alkyl substituted alloxan derivatives

1993 • 29 citations

Impaired Insulin Release after Exposure of Pancreatic Islets to Autooxidizing Dihydroxyfumarate

1981 • 16 citations