Opposing Activities of Dally-like Glypican at High and Low Levels of Wingless Morphogen Activity

Cell Signaling by Receptor Tyrosine Kinases

2010 • 7,477 citations

Cell Signaling by Receptor Tyrosine Kinases

2000 • 3,570 citations

Phase separation of integral membrane proteins in Triton X-114 solution.

1981 • 3,366 citations

Molecular diversity of heparan sulfate

2001 • 812 citations

α/β Hydrolase fold enzymes: the family keeps growing

1999 • 799 citations

Molecular diversity of heparan sulfate

2001 • 790 citations

Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome

1996 • 767 citations

Direct and Long-Range Action of a Wingless Morphogen Gradient

1996 • 736 citations

Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin

2000 • 679 citations

Regulated Diversity of Heparan Sulfate

1998 • 671 citations

Identification of Hedgehog Pathway Components by RNAi in Drosophila Cultured Cells

2003 • 518 citations

Senseless, a Zn Finger Transcription Factor, Is Necessary and Sufficient for Sensory Organ Development in Drosophila

2000 • 509 citations

Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion

1998 • 505 citations

HOW GLYCOSYL-PHOSPHATIDYLINOSITOL-ANCHORED MEMBRANE PROTEINS ARE MADE

1995 • 478 citations

Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling

1999 • 474 citations

Regulation of Wnt Signaling and Embryo Patterning by an Extracellular Sulfatase

2001 • 462 citations

The Zebrafish Glypican Knypek Controls Cell Polarity during Gastrulation Movements of Convergent Extension

2001 • 446 citations

Wingless gradient formation in the Drosophila wing

2000 • 437 citations

QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling

2003 • 424 citations

Developmental Regulation of Neural Response to FGF-1 and FGF-2 by Heparan Sulfate Proteoglycan

1993 • 420 citations

Long-range action of Wingless organizes the dorsal-ventral axis of the Drosophila wing

1997 • 416 citations

Argosomes

2001 • 413 citations

The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila

1999 • 393 citations

Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless

2001 • 370 citations

Hedgehog Movement Is Regulated through tout velu–Dependent Synthesis of a Heparan Sulfate Proteoglycan

1999 • 367 citations

Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development

1999 • 367 citations

The wingless signalling pathway and the patterning of the wing margin in Drosophila

1994 • 354 citations

Antagonistic Interactions Between Wingless and Decapentaplegic Responsible for Dorsal-Ventral Pattern in the Drosophila Leg

1996 • 322 citations

Heparan sulfate: growth control with a restricted sequence menu

2001 • 310 citations

Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction.

1996 • 307 citations

Self-Enhanced Ligand Degradation Underlies Robustness of Morphogen Gradients

2003 • 292 citations

Pattern formation in a secondary field: a hierarchy of regulatory genes subdivides the developing Drosophila wing disc into discrete subregions

1993 • 292 citations

The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis

1997 • 290 citations

Structural Analysis of Glycosaminoglycans inDrosophila and Caenorhabditis elegans and Demonstration That tout-velu, a Drosophila Gene Related to EXT Tumor Suppressors, Affects Heparan Sulfate in Vivo

2000 • 287 citations

Genetic evidence that heparin-like glycosaminoglycans are involved in wingless signaling

1997 • 257 citations

dally, a Drosophila glypican, controls cellular responses to the TGF-β-related morphogen, Dpp

1997 • 241 citations

HSPG Modification by the Secreted Enzyme Notum Shapes the Wingless Morphogen Gradient

2002 • 238 citations

Drosophilaglypicans control the cell-to-cell movement of Hedgehog by a dynamin-independent process

2004 • 237 citations

Sequence Analysis of Heparan Sulfate Epitopes with Graded Affinities for Fibroblast Growth Factors 1 and 2

2001 • 225 citations

Dally regulates Dpp morphogen gradient formation in theDrosophilawing

2003 • 223 citations

Heparan Sulfate Proteoglycans Retain Noggin at the Cell Surface

2002 • 209 citations

Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila

1997 • 196 citations

Selectively Desulfated Heparin Inhibits Fibroblast Growth Factor-induced Mitogenicity and Angiogenesis

2000 • 174 citations

Spatial Regulation of Wingless Morphogen Distribution and Signaling by Dally-like Protein

2004 • 164 citations

RNAi Triggered by Symmetrically Transcribed Transgenes in Drosophila melanogaster

2002 • 150 citations

Wingless and Notch signaling provide cell survival cues and control cell proliferation during wing development

2003 • 144 citations

The role of glypicans in mammalian development

2002 • 143 citations

The glypican Dally-like is required for Hedgehog signalling in the embryonic epidermis ofDrosophila

2003 • 142 citations

Release of GPI-anchored membrane proteins by a cell-associated GPI-specific phospholipase D.

1994 • 136 citations

UDP–sugar transporter implicated in glycosylation and processing of Notch

2001 • 129 citations

Wingful, an extracellular feedback inhibitor of Wingless

2002 • 121 citations

Cellular functions of proteoglycans—an overview

2001 • 119 citations

Dual role of the fringe connection gene in both heparan sulphate and fringe-dependent signalling events

2001 • 116 citations

Biosynthesis of heparin. Purification of a 110-kDa mouse mastocytoma protein required for both glucosaminyl N-deacetylation and N-sulfation

1991 • 92 citations

Interactions between Wingless and DFz2 during Drosophila wing development

1998 • 87 citations

Mechanisms Underlying Preferential Assembly of Heparan Sulfate on Glypican-1

2001 • 84 citations

Xenopus Cyr61regulates gastrulation movements and modulates Wnt signalling

2003 • 80 citations

Glypican 4 modulates FGF signalling and regulates dorsoventral forebrain patterning inXenopusembryos

2003 • 76 citations

Mammalian glycophosphatidylinositol anchor transfer to proteins and posttransfer deacylation

1998 • 72 citations

Genetic dissection of proteoglycan function in Drosophila and C. elegans

2001 • 71 citations

Regulation of dally, an Integral Membrane Proteoglycan, and Its Function during Adult Sensory Organ Formation of Drosophila

2001 • 70 citations

Copper-dependent Autocleavage of Glypican-1 Heparan Sulfate by Nitric Oxide Derived from Intrinsic Nitrosothiols

2002 • 44 citations

Deleted Work

1955 • 0 citations