Heparan sulfate: growth control with a restricted sequence menu

MATRIX PROTEOGLYCANS: From Molecular Design to Cellular Function

1998 • 1,623 citations

Proteoglycans: Structures And Interactions

1991 • 1,596 citations

Crystal Structure of a Ternary FGF-FGFR-Heparin Complex Reveals a Dual Role for Heparin in FGFR Binding and Dimerization

2000 • 1,146 citations

A Novel Role for 3-O-Sulfated Heparan Sulfate in Herpes Simplex Virus 1 Entry

1999 • 1,019 citations

Automated Solid-Phase Synthesis of Oligosaccharides

2001 • 888 citations

Molecular diversity of heparan sulfate

2001 • 812 citations

Molecular diversity of heparan sulfate

2001 • 790 citations

Heparin Structure and Interactions with Basic Fibroblast Growth Factor

1996 • 789 citations

Untitled

1996 • 780 citations

Specificities of heparan sulphate proteoglycans in developmental processes

2000 • 706 citations

Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin

2000 • 679 citations

The anticoagulant activation of antithrombin by heparin

1997 • 659 citations

Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion

1998 • 505 citations

Regulation of growth factor activation by proteoglycans: What is the role of the low affinity receptors?

1995 • 478 citations

Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase

1998 • 453 citations

Minimal sequence in heparin/heparan sulfate required for binding of basic fibroblast growth factor.

1993 • 449 citations

Disruption of Gastrulation and Heparan Sulfate Biosynthesis in EXT1-Deficient Mice

2000 • 408 citations

N.m.r. and molecular-modelling studies of the solution conformation of heparin

1993 • 400 citations

Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena

2001 • 398 citations

The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila

1999 • 393 citations

Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena

2001 • 369 citations

Heparin and heparan sulfate: biosynthesis, structure and function

2000 • 306 citations

Conformation and dynamics of heparin and heparan sulfate

2000 • 304 citations

Domain Structure of Heparan Sulfates from Bovine Organs

1996 • 281 citations

Heparan Sulfate Oligosaccharides Require 6-O-Sulfation for Promotion of Basic Fibroblast Growth Factor Mitogenic Activity

1998 • 276 citations

Defining the Interleukin-8-binding Domain of Heparan Sulfate

1998 • 259 citations

Generation and Application of Type-specific Anti-Heparan Sulfate Antibodies Using Phage Display Technology

1998 • 258 citations

The Elusive Functions of Proteoglycans

2000 • 258 citations

The Interaction of the Transforming Growth Factor-βs with Heparin/Heparan Sulfate Is Isoform-specific

1997 • 247 citations

Molecular distinctions between heparan sulphate and heparin. Analysis of sulphation patterns indicates that heparan sulphate and heparin are separate families of N-sulphated polysaccharides

1985 • 243 citations

Liver heparan sulfate structure. A novel molecular design

1994 • 235 citations

Series Introduction: Heparan sulfate proteoglycans: intricate molecules with intriguing functions

2001 • 234 citations

Sequence Analysis of Heparan Sulfate Epitopes with Graded Affinities for Fibroblast Growth Factors 1 and 2

2001 • 225 citations

Specific heparan sulfate saccharides mediate the activity of basic fibroblast growth factor.

1994 • 202 citations

Specific Binding of the Chemokine Platelet Factor 4 to Heparan Sulfate

1997 • 197 citations

Heparan sulfate: lessons from knockout mice

2001 • 192 citations

Fibroblast growth factor receptor signalling is dictated by specific heparan sulphate saccharides

1999 • 189 citations

Structural Modification of Fibroblast Growth Factor-binding Heparan Sulfate at a Determinative Stage of Neural Development

1998 • 183 citations

Proteoglycans

2000 • 165 citations

Heparan sulfate: lessons from knockout mice

2001 • 159 citations

Specificity of glycosaminoglycan–protein interactions

2018 • 158 citations

Distribution of iduronate 2-sulphate residues in heparan sulphate. Evidence for an ordered polymeric structure

1991 • 150 citations

Presence of N-Unsubstituted Glucosamine Units in Native Heparan Sulfate Revealed by a Monoclonal Antibody

1995 • 147 citations

Amino acid determinants that drive heparan sulfate assembly in a proteoglycan.

1994 • 145 citations

Identification and concerted function of two receptor binding surfaces on basic fibroblast growth factor required for mitogenesis.

1994 • 139 citations

Molecular organization of the interferon γ-binding domain in heparan sulphate

1995 • 134 citations

Glycosaminoglycan-protein interactions: a question of specificity

1994 • 129 citations

Highly Sensitive Sequencing of the Sulfated Domains of Heparan Sulfate

1999 • 128 citations

Bio-specific sequences and domains in heparan sulphate and the regulation of cell growth and adhesion

1998 • 127 citations

Regulation of FGF-1 mitogenic activity by heparan sulfate oligosaccharides is dependent on specific structural features: differential requirements for the modulation of FGF-1 and FGF-2

2000 • 116 citations

The Heparan Sulfate Binding Sequence of Interferon-γ Increased the On Rate of the Interferon-γ-Interferon-γ Receptor Complex Formation

1998 • 115 citations

Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding.

1999 • 114 citations

Proteoglycans: Master regulators of molecular encounter?

1998 • 113 citations

Basic Fibroblast Growth Factor Binds Its Receptors, Is Internalized, and Stimulates DNA Synthesis in Balb/c3T3 Cells in the Absence of Heparan Sulfate

1996 • 112 citations

Heparan Sulfate d-Glucosaminyl 3-O-Sulfotransferase-3A SulfatesN-Unsubstituted Glucosamine Residues

1999 • 99 citations

Fibroblast Growth Factor-2 Stimulation of p42/44MAPKPhosphorylation and IκB Degradation Is Regulated by Heparan Sulfate/Heparin in Rat Mammary Fibroblasts

2000 • 69 citations

Receptors for fibroblast growth factors

1995 • 63 citations

Fibroblast growth factors 1 and 2 are distinct in oligomerization in the presence of heparin-like glycosaminoglycans

1999 • 53 citations

Monomer Complexes of Basic Fibroblast Growth Factor and Heparan Sulfate Oligosaccharides Are the Minimal Functional Unit for Cell Activation

1999 • 50 citations

Structural Diversity of N-Sulfated Heparan Sulfate Domains: Distinct Modes of Glucuronyl C5 Epimerization, Iduronic Acid 2-O-Sulfation, and Glucosamine 6-O-Sulfation

2000 • 45 citations

The Interaction and Regulation of Basic and Acidic Fibroblast Growth Factors by Heparan Sulphate.

1998 • 18 citations