Mechanism of photoreceptor cGMP phosphodiesterase inhibition by its gamma-subunits.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Laser desorption ionization of proteins with molecular masses exceeding 10,000 daltons

1988 • 5,560 citations

The 2.2 Å crystal structure of transducin-α complexed with GTPγS

1993 • 788 citations

Rhodopsin content in the outer segment membranes of bovine and frog retinal rods

1974 • 730 citations

Visual excitation and recovery

1991 • 530 citations

Isolation and characterization of cGMP phosphodiesterase from bovine rod outer segments.

1979 • 448 citations

Purification and characterization of the gamma regulatory subunit of the cyclic GMP phosphodiesterase from retinal rod outer segments.

1982 • 336 citations

Molecular mechanism of visual transduction

1989 • 312 citations

Transduction mechanisms of vertebrate and invertebrate photoreceptors.

1994 • 286 citations

Purification and properties of the light-activated cyclic nucleotide phosphodiesterase of rod outer segments

1975 • 271 citations

cGMP phosphodiesterase of retinal rods is regulated by two inhibitory subunits.

1988 • 246 citations

The structure of a bovine lung cGMP-binding, cGMP-specific phosphodiesterase deduced from a cDNA clone.

1993 • 169 citations

Bovine cone photoreceptor cGMP phosphodiesterase structure deduced from a cDNA clone.

1990 • 160 citations

Subunit stoichiometry of retinal rod cGMP phosphodiesterase

1990 • 138 citations

[72] Real time assay of rod disk membrane cGMP phosphodiesterase and its controller enzymes

1982 • 125 citations

Beta-subunit of bovine rod photoreceptor cGMP phosphodiesterase. Comparison with the phosphodiesterase family.

1990 • 108 citations

Activation mechanism of retinal rod cyclic GMP phosphodiesterase probed by fluorescein-labeled inhibitory subunit

1990 • 86 citations

Two-site high-affinity interaction between inhibitory and catalytic subunits of rod cyclic GMP phosphodiesterase

1992 • 79 citations

Active sites of the cyclic GMP phosphodiesterase γ‐subunit of retinal rod outer segments

1988 • 69 citations

Activation and solubilization of the retinal cGMP‐specific phosphodiesterase by limited proteolysis

1991 • 67 citations

Functional regions of the inhibitory subunit of retinal rod cGMP phosphodiesterase identified by site-specific mutagenesis and fluorescence spectroscopy

1992 • 66 citations

The Carboxyl Terminus of the γ-Subunit of Rod cGMP Phosphodiesterase Contains Distinct Sites of Interaction with the Enzyme Catalytic Subunits and the α-Subunit of Transducin

1995 • 64 citations

Expression in bacteria of functional inhibitory subunit of retinal rod cGMP phosphodiesterase.

1989 • 62 citations

Amino acid sequence of the cyclic GMP stimulated cyclic nucleotide phosphodiesterase from bovine heart

1990 • 60 citations

Comparison of the phosphodiesterase inhibitory subunit interactions of frog and bovine rod outer segments

1989 • 53 citations

Domain mapping of the retinal cyclic GMP phosphodiesterase γ-subunit. Function of the domains encoded by the three exons of the γ-subunit gene

1992 • 50 citations

The three-dimensional structure of c-H-ras p21: implications for oncogene and G protein studies

1988 • 41 citations

Affinities of bovine photoreceptor cGMP phosphodiesterases for rod and cone inhibitory subunits

1993 • 34 citations

Identification of the retinal cyclic GMP phosphodiesterase inhibitory gamma-subunit interaction sites on the catalytic alpha-subunit.

1991 • 23 citations

Identification of the γ-subunit interaction sites in the retinal cyclic-GMP phosphodiesterase β-subunit

1991 • 12 citations