A Novel Mechanism of Cooperation between c-Kit and Erythropoietin Receptor

BCL-2 FAMILY: Regulators of Cell Death

1998 • 1,687 citations

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

1991 • 1,321 citations

Stat5a and Stat5b Proteins Have Essential and Nonessential, or Redundant, Roles in Cytokine Responses

1998 • 1,316 citations

Massive Cell Death of Immature Hematopoietic Cells and Neurons in Bcl-x-Deficient Mice

1995 • 1,167 citations

Hereditary Anemias of the Mouse: A Review for Geneticists

1979 • 1,141 citations

Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor

1995 • 1,027 citations

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2.

1993 • 959 citations

Involvement of Granulocyte-Macrophage Colony-Stimulating Factor in Pulmonary Homeostasis

1994 • 883 citations

Erythropoietin Retards DNA Breakdown and Prevents Programmed Death in Erythroid Progenitor Cells

1990 • 837 citations

Checkpoints of dueling dimers foil death wishes

1994 • 806 citations

Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1.

1996 • 763 citations

Fetal Anemia and Apoptosis of Red Cell Progenitors in Stat5a−/−5b−/− Mice

1999 • 710 citations

Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells.

1994 • 574 citations

Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice.

1989 • 495 citations

Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation

1995 • 372 citations

GATA-1 and Erythropoietin Cooperate to Promote Erythroid Cell Survival by Regulating bcl-xL Expression

1999 • 364 citations

Development of hematopoietic cells lacking transcription factor GATA-1

1995 • 362 citations

Erythroid-Cell-Specific Properties of Transcription Factor GATA-1 Revealed by Phenotypic Rescue of a Gene-Targeted Cell Line

1997 • 351 citations

Erythropoietin can promote erythroid progenitor survival by repressing apoptosis through Bcl-XL and Bcl-2

1996 • 348 citations

Characterization of A1, a novel hemopoietic-specific early-response gene with sequence similarity to bcl-2.

1993 • 336 citations

Interaction of the erythropoietin and stem-cell-factor receptors

1995 • 309 citations

Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis.

1995 • 306 citations

The Erythropoietin Receptor: Structure, Activation and Intracellular Signal Transduction

1999 • 235 citations

Activation of the erythropoietin receptor promoter by transcription factor GATA-1.

1991 • 225 citations

Functional interaction of erythropoietin and stem cell factor receptors is essential for erythroid colony formation

1997 • 174 citations

The Roles of Bcl-XL and Apopain in the Control of Erythropoiesis by Erythropoietin

1997 • 167 citations

Erythropoietin is both a mitogen and a survival factor

1991 • 158 citations

Survival or death of individual proerythroblasts results from differing erythropoietin sensitivities: a mechanism for controlled rates of erythrocyte production

1993 • 153 citations

GATA-1 transactivates erythropoietin receptor gene, and erythropoietin receptor-mediated signals enhance GATA-1 gene expression

1991 • 148 citations

Apoptosis induced by erythroid differentiation of human leukemia cell lines is inhibited by Bcl-XL

1996 • 138 citations

bcl-x Prevents Apoptotic Cell Death of Both Primitive and Definitive Erythrocytes at the End of Maturation

1999 • 134 citations

Apoptosis and hematopoiesis in murine fetal liver

1993 • 106 citations

Signaling Through the Interaction of Membrane-Restricted Stem Cell Factor and c-kit Receptor Tyrosine Kinase: Genetic Evidence for a Differential Role in Erythropoiesis

1998 • 90 citations

Apoptosis in erythroid progenitors deprived of erythropoietin occurs during the G1 and S phases of the cell cycle without growth arrest or stabilization of wild-type p53.

1994 • 73 citations

Regulation of transcription of the human erythropoietin receptor gene by proteins binding to GATA–1 and Sp1 motifs

1995 • 67 citations

Signal transduction through the receptor for erythropoietin

1993 • 47 citations

Bcl-2 Targeted Overexpression Into the Erythroid Lineage of Transgenic Mice Delays But Does Not Prevent the Apoptosis of Erythropoietin-Deprived Erythroid Progenitors

1997 • 44 citations

Onset of erythropoietin response in murine erythroid colony-forming units: assignment to early S-phase in a specific cell generation

1992 • 28 citations

The Presence of Novel Amino Acids in the Cytoplasmic Domain of Stem Cell Factor Results in Hematopoietic Defects inSteel17H Mice

1999 • 25 citations

Induction of the Erythropoietin Receptor Gene and Acquisition of Responsiveness to Erythropoietin by Stem Cell Factor in HML/SE, a Human Leukemic Cell Line

1998 • 21 citations

Onset of erythropoietin response in murine erythroid colony-forming units: assignment to early S-phase in a specific cell generation

1992 • 20 citations

The Fate of Erythroid Progenitor Cells^a

1994 • 15 citations