GATA-1 and Erythropoietin Cooperate to Promote Erythroid Cell Survival by Regulating bcl-xL Expression

The Bcl-2 Protein Family: Arbiters of Cell Survival

1998 • 5,359 citations

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

1993 • 3,111 citations

AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis

1996 • 1,885 citations

Molecular thanatopsis: a discourse on the BCL2 family and cell death

1996 • 1,412 citations

Life, death, and the pursuit of apoptosis.

1996 • 1,333 citations

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

1991 • 1,321 citations

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis.

1996 • 1,195 citations

Massive Cell Death of Immature Hematopoietic Cells and Neurons in Bcl-x-Deficient Mice

1995 • 1,167 citations

A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis

1991 • 1,074 citations

Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor

1995 • 1,027 citations

Hematopoietic commitment during embryonic stem cell differentiation in culture.

1993 • 919 citations

GATA-binding transcription factors in hematopoietic cells

1992 • 845 citations

Erythropoietin Retards DNA Breakdown and Prevents Programmed Death in Erythroid Progenitor Cells

1990 • 837 citations

Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1.

1996 • 763 citations

GATA-binding transcription factors in hematopoietic cells

1992 • 727 citations

FOG, a Multitype Zinc Finger Protein, Acts as a Cofactor for Transcription Factor GATA-1 in Erythroid and Megakaryocytic Differentiation

1997 • 723 citations

A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development

1997 • 683 citations

Estrogen Receptor-Associated Proteins: Possible Mediators of Hormone-Induced Transcription

1994 • 645 citations

Bcl-2 Rescues T Lymphopoiesis in Interleukin-7 Receptor–Deficient Mice

1997 • 603 citations

The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function

1988 • 588 citations

Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells.

1994 • 574 citations

Localisation of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor.

1986 • 533 citations

Bcl-2 Can Rescue T Lymphocyte Development in Interleukin-7 Receptor–Deficient Mice but Not in Mutant rag-1 −/− Mice

1997 • 503 citations

Differentiation in erythroleukemic cells and their somatic hybrids.

1975 • 447 citations

Differential effects of an erythropoietin receptor gene disruption on primitive and definitive erythropoiesis.

1996 • 439 citations

bcl-xLx is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria

1994 • 435 citations

GATA transcription factors: key regulators of hematopoiesis.

1995 • 430 citations

p300 is a component of an estrogen receptor coactivator complex.

1996 • 399 citations

Development of hematopoietic cells lacking transcription factor GATA-1

1995 • 362 citations

Erythroid-Cell-Specific Properties of Transcription Factor GATA-1 Revealed by Phenotypic Rescue of a Gene-Targeted Cell Line

1997 • 351 citations

Erythropoietin can promote erythroid progenitor survival by repressing apoptosis through Bcl-XL and Bcl-2

1996 • 348 citations

Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis.

1995 • 306 citations

Enforced Expression of Bcl-2 in Monocytes Rescues Macrophages and Partially Reverses Osteopetrosis in op/op Mice

1997 • 292 citations

The Biochemical development of the fetus and neonate

1982 • 264 citations

Bclx regulates the survival of double-positive thymocytes.

1995 • 249 citations

Friend spleen focus-forming virus glycoprotein gp55 interacts with the erythropoietin receptor in the endoplasmic reticulum and affects receptor metabolism.

1990 • 244 citations

A “knockdown” mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1

1997 • 228 citations

Activation of the erythropoietin receptor promoter by transcription factor GATA-1.

1991 • 225 citations

Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner.

1993 • 218 citations

Biology of erythropoietin.

1998 • 207 citations

Genomic organization, promoter region analysis, and chromosome localization of the mouse bcl-x gene.

1997 • 188 citations

Hematopoiesis: how does it happen?

1995 • 169 citations

The Roles of Bcl-XL and Apopain in the Control of Erythropoiesis by Erythropoietin

1997 • 167 citations

Survival or death of individual proerythroblasts results from differing erythropoietin sensitivities: a mechanism for controlled rates of erythrocyte production

1993 • 153 citations

Expression and function of c-Kit in fetal hemopoietic progenitor cells: transition from the early c-Kit-independent to the late c-Kit-dependent wave of hemopoiesis in the murine embryo

1993 • 145 citations

Apoptosis induced by erythroid differentiation of human leukemia cell lines is inhibited by Bcl-XL

1996 • 138 citations

Cloning and molecular characterization of mouse bcl-x in B and T lymphocytes.

1994 • 133 citations

Estrogen-Induced Apoptosis by Inhibition of the Erythroid Transcription Factor GATA-1

1996 • 112 citations

Selective regulation ofBcl-X_Lby a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies

1998 • 110 citations

Distinct Signaling from Stem Cell Factor and Erythropoietin in HCD57 Cells

1997 • 98 citations

Differentiation of mouse erythroleukemia cells is blocked by late up-regulation of a c-myb transgene.

1990 • 97 citations

A Novel Bcl-x Isoform Connected to the T Cell Receptor Regulates Apoptosis in T Cells

1997 • 95 citations

The gene for erythropoietin receptor is expressed in multipotential hematopoietic and embryonal stem cells: evidence for differentiation stage-specific regulation.

1992 • 87 citations

Control of hematopoietic differentiation: Lack of specificity in signaling by cytokine receptors

1998 • 82 citations

Intermediates in degradation of the erythropoietin receptor accumulate and are degraded in lysosomes

1993 • 75 citations

Erythropoietin-dependent Inhibition of Apoptosis Is Supported by Carboxyl-truncated Receptor Forms and Blocked by Dominant-negative Forms of Jak2

1995 • 59 citations

Bcl-2 Targeted Overexpression Into the Erythroid Lineage of Transgenic Mice Delays But Does Not Prevent the Apoptosis of Erythropoietin-Deprived Erythroid Progenitors

1997 • 44 citations

Severe Energy Impairment Consequent to Inactivation of Mitochondrial ATP Synthase as an Early Event in Cell Death: A Mechanism for the Selective Sensitivity to H2O2 of Differentiating Erythroleukemia Cells

1998 • 28 citations