Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice.

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination

1977 • 3,548 citations

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

1987 • 1,627 citations

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

1988 • 1,390 citations

The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

1988 • 1,336 citations

[42] Detection and quantification of phosphotyrosine in proteins

1983 • 1,184 citations

Hereditary Anemias of the Mouse: A Review for Geneticists

1979 • 1,141 citations

Ontogeny of the Haemopoietic System: Yolk Sac Origin of In Vivo and In Vitro Colony Forming Cells in the Developing Mouse Embryo*

1970 • 1,031 citations

Functional macrophage cell lines transformed by abelson leukemia virus

1978 • 895 citations

Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family-oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.

1988 • 727 citations

Erythroleukemic Differentiation

1978 • 694 citations

After Insulin Binds

1987 • 687 citations

A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase gene family

1986 • 647 citations

Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines.

1983 • 559 citations

Gene‐induced embryological modifications of primordial germ cells in the mouse

1957 • 556 citations

Differentiation of a cell line of myeloid leukemia

1969 • 520 citations

Fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient W/Wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosal mast cells.

1985 • 503 citations

Reticulum Cell Sarcoma: An Effector Cell in Antibody-Dependent Cell-Mediated Immunity

1975 • 426 citations

Lysozyme synthesis by established human and murine histiocytic lymphoma cell lines.

1976 • 388 citations

Identification of Macrophage-Like Characteristics in a Cultured Murine Tumor Line

1975 • 374 citations

Decreased production of mast cells in S1/S1d anemic mice

1979 • 372 citations

Rearrangements of the cellular p53 gene in erythroleukaemic cells transformed by Friend virus

1985 • 334 citations

Competitive repopulation: a new assay for long-term stem cell functional capacity

1980 • 332 citations

Spleen-Colony Formation in Anemic Mice of Genotype WW ^V

1964 • 331 citations

Antibodies against a synthetic peptide as a probe for the kinase activity of the avian EGF receptor and v-erbb protein

1985 • 310 citations

Self-renewal and differentiation of interleukin-3-dependent multipotent stem cells are modulated by stromal cells and serum factors

1986 • 288 citations

Coculture of interleukin 3-dependent mouse mast cells with fibroblasts results in a phenotypic change of the mast cells.

1986 • 287 citations

Three stages of erythropoietic progenitor cell differentiation distinguished by a number of physical and biologic properties

1978 • 269 citations

Novel immunoglobulin heavy chains are produced from DJH gene segment rearrangements in lymphoid cells

1984 • 261 citations

ANALYSIS OF PLEIOTROPISM AT THE DOMINANT WHITE-SPOTTING (W) LOCUS OF THE HOUSE MOUSE: A DESCRIPTION OF TEN NEW W ALLELES

1981 • 241 citations

Long-term in vitro culture of murine mast cells. I. Description of a growth factor-dependent culture technique.

1981 • 208 citations

Synergism between hemopoietic growth factors (HGFs) detected by their effects on cells bearing receptors for a lineage specific HGF: Assay of hemopoietin‐1

1985 • 184 citations

c-kit protein, a transmembrane kinase: identification in tissues and characterization.

1988 • 167 citations

An experimental analysis of the pigment defect caused by mutations at the W and Sl loci in mice

1968 • 139 citations

Murine hematopoietic cells with pre-B or pre-B/myeloid characteristics are generated by in vitro transformation with retroviruses containing fes, ras, abl, and src oncogenes.

1986 • 124 citations

Continuous in vitro generation of multipotential stem cell clones from src-infected cultures

1984 • 102 citations

Regulation of hematopoiesis.

1990 • 97 citations

A new allele sash (W^sh) at theW-locus and a spontaneous recessive lethal in mice

1982 • 94 citations

Abelson leukemia virus induces lymphoid and erythroid colonies in infected fetal cell cultures

1981 • 94 citations

Macrophage colony formation supported by purified CSF-1 and/or interleukin 3 in serum-free culture: evidence for hierarchical difference in macrophage colony-forming cells

1986 • 84 citations

Normal murine melanocytes in culture

1987 • 82 citations

Proof of whole-cell implant in therapy of W-series anemia

1968 • 70 citations

The Parodi-Irgens feline sarcoma virus and simian sarcoma virus have homologous oncogenes, but in different contexts of the viral genomes

1983 • 65 citations

Isolation and induction of erythroleukemic cell lines with properties of erythroid progenitor burst-forming cell (BFU-E) and erythroid precursor cell (CFU-E).

1983 • 63 citations

Dominant Spotting, Patch, and Rump-White

1979 • 62 citations

A study of the hereditary anaemia of mice

1927 • 58 citations

Long-term in vitro culture of murine mast cells. III. Discrimination of mast cells growth factor and granulocyte-CSF.

1982 • 55 citations

The Inheritance of Black-Eyed White Spotting in Mice

1915 • 45 citations

Selective defect of natural killer and killer cell activity against lymphomas in SJL mice: low responsiveness to interferon inducers.

1983 • 32 citations

Abelson Virus Potentiates Long-Term Growth of Mature B Lymphocytes

1986 • 26 citations

Hemopoietic precursor cell defects in nonanemic but stem cell‐deficient W⁴⁴/W⁴⁴ mice

1988 • 13 citations