Upregulation of MMPs by soluble E‐cadherin in human lung tumor cells

New functions for the matrix metalloproteinases in cancer progression

2002 • 5,937 citations

Cadherin Cell Adhesion Receptors as a Morphogenetic Regulator

1991 • 3,314 citations

A matrix metalloproteinase expressed on the surface of invasive tumour cells

1994 • 2,561 citations

Changing views of the role of matrix metalloproteinases in metastasis

1997 • 1,585 citations

Basement membrane complexes with biological activity

1986 • 1,489 citations

Membrane Type 1 Matrix Metalloproteinase Digests Interstitial Collagens and Other Extracellular Matrix Macromolecules

1997 • 926 citations

Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene.

1993 • 912 citations

Inactivation of the E-Cadherin-Mediated Cell Adhesion System in Human Cancers

1998 • 846 citations

Matrix metalloproteinases in tumor invasion and metastasis

2000 • 820 citations

Cadherin-catenin complex: Protein interactions and their implications for cadherin function

1996 • 806 citations

Regulation of Cadherin Adhesive Activity

2000 • 793 citations

Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1

2001 • 685 citations

The metalloproteinase matrilysin is a target of β-catenin transactivation in intestinal tumors

1999 • 679 citations

The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis

2001 • 677 citations

Matrix metalloproteinases in tumour invasion and metastasis

1999 • 670 citations

β-Catenin Regulates the Expression of the Matrix Metalloproteinase-7 in Human Colorectal Cancer

1999 • 665 citations

Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, N-CAM, and N-cadherin

1994 • 594 citations

Matrix metalloproteinases

2000 • 533 citations

Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.

1995 • 511 citations

E-cadherin—catenin cell—cell adhesion complex and human cancer

2000 • 448 citations

Transmembrane-deletion Mutants of the Membrane-type Matrix Metalloproteinase-1 Process Progelatinase A and Express Intrinsic Matrix-degrading Activity

1996 • 392 citations

Identification of a cadherin cell adhesion recognition sequence

1990 • 382 citations

The role of matrix metalloproteases and their inhibitors in tumour invasion, metastasis and angiogenesis

1994 • 333 citations

Immunohistochemical distribution of type IV collagenase in normal, benign, and malignant breast tissue.

1990 • 323 citations

Identification of membrane-type matrix metalloproteinase-1 as a target of the β-catenin/Tcf4 complex in human colorectal cancers

2002 • 235 citations

Soluble E-cadherin fragments increased in circulation of cancer patients

1994 • 178 citations

High level of MT-MMP expression is associated with invasiveness of cervical cancer cells

1996 • 165 citations

Transition from the noninvasive to the invasive phenotype and loss of alpha-catenin in human colon cancer cells.

1995 • 164 citations

Curbing the nuclear activities of β‐catenin

2000 • 163 citations

A Novel Family of Cyclic Peptide Antagonists Suggests That N-cadherin Specificity Is Determined by Amino Acids That Flank the HAV Motif

2000 • 154 citations

Identification of an N-cadherin Motif That Can Interact with the Fibroblast Growth Factor Receptor and Is Required for Axonal Growth

2001 • 142 citations

Expression of matrix metalloproteinases and their inhibitors in human bronchopulmonary carcinomas: Quantificative and morphological analyses

1997 • 133 citations

Dominant negative inhibition of the association between beta-catenin and c-erbB-2 by N-terminally deleted beta-catenin suppresses the invasion and metastasis of cancer cells.

1996 • 110 citations

Contribution of MT1-MMP and of human laminin-5 γ2 chain degradation to mammary epithelial cell migration

2001 • 110 citations

Retinoic acid modulates both invasion and plasma membrane ruffling of MCF-7 human mammary carcinoma cells in vitro

1991 • 98 citations

Cell adhesion molecules in bladder cancer: soluble serum E-cadherin correlates with predictors of recurrence

1996 • 96 citations

Expression of E-cadherin and catenins in invasive mammary carcinomas.

1997 • 93 citations

Inhibition of adhesion and induction of epithelial cell invasion by HAV-containing E-cadherin-specific peptides

1999 • 92 citations

Soluble forms of the adhesion molecule E-cadherin in urine.

1995 • 75 citations

Cadherin/catenin complex: A target for antiinvasive therapy?

1996 • 72 citations

Cytoplasmic Redistribution of E-Cadherin-Catenin Adhesion Complex Is Associated with Down-Regulated Tyrosine Phosphorylation of E-Cadherin in Human Bronchopulmonary Carcinomas

1998 • 67 citations

Epithelial‐to‐mesenchymal transition in hpv‐33‐transfected cervical keratinocytes is associated with increased invasiveness and expression of gelatinase a

1994 • 55 citations

Fibroblast growth factor receptors contain a conserved HAV region common to cadherins and influenza strain a hemagglutinins: A role in protein-protein interactions?

1992 • 47 citations

Association of fibroblastoid features with the invasive phenotype in human bronchial cancer cell lines.

1997 • 46 citations

Inverse Relation of Autocrine Motility Factor Receptor and E-Cadherin Expression following MDCK Epithelial Cell Transformation

1996 • 20 citations

Matrix Metalloproteinases in Breast Cancer

1996 • 15 citations