Alpha-kinases: analysis of the family and comparison with conventional protein kinases

The Protein Kinase Complement of the Human Genome

2002 • 7,708 citations

Protein Structure Comparison by Alignment of Distance Matrices

1993 • 3,989 citations

Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification.

1995 • 2,534 citations

The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification ¹

1995 • 2,199 citations

The Conformational Plasticity of Protein Kinases

2002 • 1,691 citations

The Draft Genome of Ciona intestinalis : Insights into Chordate and Vertebrate Origins

2002 • 1,611 citations

cAMP-DEPENDENT PROTEIN KINASE: FRAMEWORK FOR A DIVERSE FAMILY OF REGULATORY ENZYMES

1990 • 1,121 citations

Evolution of protein kinase signaling from yeast to man

2002 • 956 citations

Structure of a Peptide Inhibitor Bound to the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

1991 • 949 citations

Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

1997 • 929 citations

LTRPC7 is a Mg·ATP-regulated divalent cation channel required for cell viability

2001 • 900 citations

Structural classification of zinc fingers: SURVEY AND SUMMARY

2003 • 852 citations

The TRP Channels, a Remarkably Functional Family

2002 • 822 citations

Automated analysis of interatomic contacts in proteins.

1999 • 797 citations

Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family

2002 • 758 citations

TRP-PLIK, a Bifunctional Protein with Kinase and Ion Channel Activities

2001 • 714 citations

Structural Basis for Control by Phosphorylation

2001 • 600 citations

Kinetic and Catalytic Mechanisms of Protein Kinases

2001 • 584 citations

Mutation of TRPM6 causes familial hypomagnesemia with secondary hypocalcemia

2002 • 543 citations

How do protein kinases recognize their substrates?

1996 • 470 citations

Phosphorylation of elongation factor 2 by EF-2 kinase affects rate of translation

1988 • 447 citations

Dynamics of cAMP-Dependent Protein Kinase

2001 • 385 citations

Structural Framework for the Protein Kinase Family

1992 • 333 citations

Structural Basis for the Autoinhibition of Calcium/Calmodulin-Dependent Protein Kinase I

1996 • 329 citations

When is a lipid kinase not a lipid kinase? When it is a protein kinase

1995 • 315 citations

cAMP‐dependent protein kinase: Crystallographic insights into substrate recognition and phosphotransfer

1994 • 279 citations

Crystal Structure of the Atypical Protein Kinase Domain of a TRP Channel with Phosphotransferase Activity

2001 • 268 citations

A cDNA resource from the basal chordate Ciona intestinalis

2002 • 244 citations

Mechanisms of signaling and related enzymes

1997 • 243 citations

Mechanisms of signaling and related enzymes

1997 • 223 citations

The structural basis for substrate recognition and control by protein kinases¹

1998 • 204 citations

Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase

1997 • 200 citations

Recognition of analogous and homologous protein folds: analysis of sequence and structure conservation 1 1Edited by F. E. Cohen

1997 • 197 citations

The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition

1997 • 197 citations

Mapping the transition state for ATP hydrolysis: implications for enzymatic catalysis

1995 • 196 citations

Structural Basis for Nucleotide Exchange and Competition with tRNA in the Yeast Elongation Factor Complex eEF1A:eEF1Bα

2000 • 175 citations

Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential

1997 • 150 citations

Elongation factor‐2 kinase and its newly discovered relatives

2002 • 148 citations

cAMP-Dependent Protein Kinase

2010 • 130 citations

Human members of the eukaryotic protein kinase family

2002 • 117 citations

Structure of an EF-Tu Complex with a Thiazolyl Peptide Antibiotic Determined at 2.35 Å Resolution: Atomic Basis for GE2270A Inhibition of EF-Tu^,

1999 • 108 citations

Structure of Pyruvate Dehydrogenase Kinase

2001 • 99 citations

Familial hypomagnesemia maps to chromosome 9q, not to the X chromosome: genetic linkage mapping and analysis of a balanced translocation breakpoint

1997 • 96 citations

Identification of two phosphorylated threonines in the tail region of Dictyostelium myosin II.

1988 • 96 citations

Structural Analysis of Myosin Heavy Chain Kinase A from Dictyostelium

1995 • 94 citations

Elongation factor‐2 kinase: effective inhibition by the novel protein kinase inhibitor rottlerin and relative insensitivity towards staurosporine

1994 • 89 citations

Replacement of threonine residues by serine and alanine in a phosphorylatable heavy chain fragment of Dictyostelium myosin II

1990 • 81 citations

2.0 Å refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with a peptide inhibitor and detergent

1993 • 73 citations

Dictyostelium myosin heavy chain kinase A regulates myosin localization during growth and development.

1996 • 72 citations

A conserved helix motif complements the protein kinase core.

1993 • 71 citations

Is There a Catalytic Base in the Active Site of cAMP-Dependent Protein Kinase?

1997 • 70 citations

Importance of the A-helix of the catalytic subunit of cAMP-dependent protein kinase for stability and for orienting subdomains at the cleft interface

1997 • 62 citations

Mapping the Functional Domains of Elongation Factor-2 Kinase

2000 • 61 citations

[Novel type of signaling molecules: protein kinases covalently linked to ion channels].

2001 • 59 citations

Mapping of the Novel Protein Kinase Catalytic Domain of Dictyostelium Myosin II Heavy Chain Kinase A

1997 • 58 citations

Differential localization in cells of myosin II heavy chain kinases during cytokinesis and polarized migration.

2002 • 56 citations

Analysis of the domain structure of elongation factor‐2 kinase by mutagenesis

1999 • 55 citations

Catalytic Subunit of Cyclic AMP-Dependent Protein Kinase

1999 • 50 citations

A Novel Myocyte-specific Gene MidoriPromotes the Differentiation of P19CL6 Cells into Cardiomyocytes

2001 • 50 citations

Identification of a Protein Kinase from Dictyosteliumwith Homology to the Novel Catalytic Domain of Myosin Heavy Chain Kinase A

1997 • 50 citations

cAMP-dependent protein kinase defines a family of enzymes

1993 • 40 citations

The NTP phosphate donor in kinase reactions: is ATP a monopolist?

1996 • 35 citations

Specific Phosphorylation of Threonine by theDictyostelium Myosin II Heavy Chain Kinase Family

2001 • 33 citations

Novel Myosin Heavy Chain Kinase Involved in Disassembly of Myosin II Filaments and Efficient Cleavage in MitoticDictyosteliumCells

2002 • 32 citations

Myosin heavy chain kinase B participates in the regulation of myosin assembly into the cytoskeleton

2002 • 25 citations

A New Zinc Binding Fold Underlines the Versatility of Zinc Binding Modules in Protein Evolution

2002 • 22 citations

Crystal structures of the catalytic subunit of cAMP-dependent protein kinase reveal general features of the protein kinase family.

1993 • 19 citations