The NTP phosphate donor in kinase reactions: is ATP a monopolist?

Protein kinase C - a question of specificity

1994 • 958 citations

Mammalian deoxyribonucleoside kinases

1995 • 572 citations

Inorganic polyphosphate: toward making a forgotten polymer unforgettable

1995 • 565 citations

Evidence that the Rous sarcoma virus transforming gene product phosphorylates phosphatidylinositol and diacylglycerol.

1984 • 476 citations

Phosphotransferase and substrate binding mechanism of the cAMP-dependent protein kinase catalytic subunit from porcine heart as deduced from the 2.0 A structure of the complex with Mn2+ adenylyl imidodiphosphate and inhibitor peptide PKI(5-24).

1993 • 399 citations

Human cytomegalovirus UL97 open reading frame encodes a protein that phosphorylates the antiviral nucleoside analogue ganciclovir

1992 • 394 citations

Transforming protein of avian sarcoma virus UR2 is associated with phosphatidylinositol kinase activity: possible role in tumorigenesis.

1984 • 278 citations

Dual-specificity protein kinases: will any hydroxyl do?

1992 • 235 citations

The bacterial phosphotransferase system: new frontiers 30 years later

1994 • 197 citations

Pyrophosphate‐dependent phosphofructokinase, an anaerobic glycolytic enzyme?

1991 • 170 citations

Metabolism and action of purine nucleoside analogs

1991 • 141 citations

Mutation in the UL97 open reading frame of human cytomegalovirus strains resistant to ganciclovir

1994 • 140 citations

Nucleotide specificity of human deoxycytidine kinase.

1992 • 121 citations

Properties of the src kinase purified from Rous sarcoma virus-induced rat tumors.

1982 • 108 citations

1001 Protein Kinases Redux—Towards 2000

1994 • 91 citations

Adenosine Triphosphatase Activity of Yeast Hexokinase and Its Relation to the Mechanism of the Hexokinase Reaction

1965 • 89 citations

Protein Kinase Cσ-specific Phosphorylation of the Elongation Factor eEF-1α and an eEF-1α Peptide at Threonine 431

1995 • 76 citations

Viral thymidine kinases and their relatives

1992 • 73 citations

Purification of Polyphosphate and ATP Glucose Phosphotransferase from Mycobacterium tuberculosis H37Ra: Evidence That Poly(P) and ATP Glucokinase Activities Are Catalyzed by the Same Enzyme

1993 • 65 citations

Purification and characterization of the major species of tyrosine protein kinase in rat liver.

1984 • 63 citations

A critical role for uridine nucleotides in the regulation of deoxycytidine kinase and the concentration dependence of 1-beta-D-arabinofuranosylcytosine phosphorylation in human leukemia cells.

1991 • 52 citations

The Hexokinase Isoenzyme PII of Saccharomyces cerevisiae is a Protein Kinase

1989 • 45 citations

Regulation of uridine kinase. Evidence for a regulatory site.

1986 • 42 citations

Identification of the ATP-binding domain of vaccinia virus thymidine kinase.

1990 • 40 citations

Human cytomegalovirus UL97 kinase confers ganciclovir susceptibility to recombinant vaccinia virus

1994 • 39 citations

Phosphorylase kinase, a metal ion-dependent dual specificity kinase.

1993 • 38 citations

Properties of a highly purified mitochondrial deoxyguanosine kinase

1988 • 38 citations

Multisubstrate analogs for deoxynucleoside kinases. Triphosphate end products and synthetic bisubstrate analogs exhibit identical modes of binding and are useful probes for distinguishing kinetic mechanisms.

1986 • 38 citations

The anatomy of a kinase and the control of phosphate transfer

1993 • 37 citations

Standard Free Energy Change for the Hydrolysis of the .alpha.,.beta.-Phosphoanhydride Bridge in ATP

1995 • 35 citations

Comparison of theoretical and experimental approaches to determination of conformation of nucleosides about the glycosidic bond

1980 • 33 citations

A rapid assay for protein kinases phosphorylating small polypeptides and other substrates

1983 • 33 citations

The Effect of Structural Modifications of ATP on the Yeast‐Hexokinase Reaction

1972 • 32 citations

Evidence that the Rous sarcoma virus transforming gene product is associated with glycerol kinase activity.

1983 • 29 citations

Phosphorylation of adenosine in anoxic hepatocytes by an exchange reaction catalysed by adenosine kinase

1993 • 28 citations

Nucleoside Triphosphate Donors for Nucleoside Kinases: Donor Properties of UTP with Human Deoxycytidine Kinase

1995 • 28 citations

Synthesis of deoxyribomononucleotides in Mollicutes: dependence on deoxyribose-1-phosphate and PPi

1987 • 26 citations

CTP-dependent lipid kinases of yeast

1988 • 22 citations

Protein Kinase Cδ Accepts GTP for Autophosphorylation

1995 • 21 citations

Development of inhibitors of protein kinases CKI and CKII and some related aspects, including donor and acceptor specificities and viral protein kinases.

1994 • 19 citations

[33] Preparation of protein phosphatase-resistant substrates using adenosine 5′-O-(γ-Thio)triphosphate

1988 • 18 citations

Identification of a novel casein kinase activity in HeLa cell nuclei

1989 • 16 citations

Purification, characterization, substrate and inhibitor specificity of adenosine kinase from several Eimeria species

1982 • 15 citations

Glucose Utilization by Tumor Cells: The Enzyme Hexokinase Autophosphorylates Both Its N- and C-Terminal Halves

1993 • 13 citations

Phosphoenolpyruvate‐dependent protein kinase activity in rat skeletal muscle

1983 • 12 citations

The cAMP-dependent protein kinase discriminates between prochiral hydroxyl groups

1993 • 12 citations

Protein kinase inhibitors--potential chemotherapeutic agents.

1995 • 10 citations

Guanosine 5'‐(γ‐thio) triphosphate (GTPγS) inhibits phosphorylation of insulin receptor and a novel GTP‐binding protein, G_ir, from human placenta

1994 • 8 citations

Structure of 3-isoadenosine

1988 • 8 citations

Zn2+-dependent tyrosine phosphorylation of a 68-kDa protein and its differentiation from Mg2+-dependent tyrosine phosphorylation in sheep platelets

1991 • 8 citations

Elimination of the hydroxyl groups in the ribose ring of ATP reduces its ability to phosphorylate the sarcoplasmic reticulum Ca(2+)-ATPase.

1993 • 7 citations

Phosphorylation of an 85-kd membrane protein by a novel mechanism.

1988 • 5 citations

Relatives of Watson‐Crick DNA, RNA Cross Sections^a

1986 • 5 citations