Nutrition and health aspects of free radicals and antioxidants

Free radicals in biology and medicine

1991 • 17,840 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Oxidants, antioxidants, and the degenerative diseases of aging.

1993 • 6,011 citations

Free Radicals in Biology and Medicine

1990 • 4,962 citations

Vascular endothelial cells synthesize nitric oxide from L-arginine

1988 • 4,800 citations

The Effect of Vitamin E and Beta Carotene on the Incidence of Lung Cancer and Other Cancers in Male Smokers

1994 • 4,626 citations

Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study

1993 • 4,414 citations

Fruit, vegetables, and cancer prevention: A review of the epidemiological evidence

1992 • 3,313 citations

Dietary Carcinogens and Anticarcinogens

1983 • 3,028 citations

Fenton's reagent revisited

1975 • 2,778 citations

Biochemistry of Nitric Oxide and Its Redox-Activated Forms

1992 • 2,725 citations

Prooxidant States and Tumor Promotion

1985 • 2,541 citations

Vitamin E Consumption and the Risk of Coronary Heart Disease in Men

1993 • 2,363 citations

The Pecking Order of Free Radicals and Antioxidants: Lipid Peroxidation, α-Tocopherol, and Ascorbate

1993 • 2,350 citations

Vitamin E Consumption and the Risk of Coronary Disease in Women

1993 • 2,158 citations

Phenolic antioxidants

1992 • 2,150 citations

The Reaction of no With Superoxide

1993 • 2,133 citations

HUMAN PLASMA PROTEINASE INHIBITORS

1983 • 2,129 citations

The Chemical Basis of Radiation Biology

1987 • 1,843 citations

The chemical basis of radiation biology

1987 • 1,788 citations

Nuclear Factor Kb: An Oxidative Stress-Responsive Transcription Factor of Eukaryotic Cells (A Review)

1992 • 1,421 citations

Diet and Health: What Should We Eat?

1994 • 1,024 citations

How to Characterize a Biological Antioxidant

1990 • 943 citations

Antioxidant actions of thymol, carvacrol, 6-gingerol, zingerone and hydroxytyrosol

1994 • 800 citations

Urinary 8-hydroxy-2'-deoxyguanosine as a biological marker of in vivo oxidative DNA damage.

1989 • 733 citations

Hydroxyl Free Radical Adduct of Deoxyguanosine: Sensitive Detection and Mechanisms of Formation

1986 • 660 citations

Oxidative DNA damage estimated by 8-hydroxydeoxyguanosine excretion in humans: influence of smoking, gender and body mass index

1992 • 646 citations

Modulation of fibroblast proliferation by oxygen free radicals

1990 • 617 citations

Antioxidant and pro-oxidant actions of the plant phenolics quercetin, gossypol and myricetin

1989 • 569 citations

Chemical determination of free radical-induced damage to DNA

1991 • 523 citations

Antioxidant and pro-oxidant properties of active rosemary constituents: carnosol and carnosic acid

1992 • 506 citations

Possible mechanisms for the protective role of antioxidants in wine and plant foods.

1993 • 467 citations

In search of better methods to evaluate natural antioxidants and oxidative stability in food lipids

1993 • 461 citations

Current status of antioxidant therapy

1993 • 429 citations

Flavonoids as Antioxidants

2000 • 400 citations

Long-Lived Oxidants Generated by Human Neutrophils: Characterization and Bioactivity

1983 • 396 citations

Evaluation of the antioxidant and prooxidant actions of gallic acid and its derivatives

1993 • 389 citations

Human disease, free radicals, and the oxidant/antioxidant balance

1993 • 385 citations

Routes of formation and toxic consequences of lipid oxidation products in foods

1992 • 367 citations

Iron Ion-dependent Modification of Bases in DNA by the Superoxide Radical-generating System Hypoxanthine/Xanthine Oxidase

1989 • 363 citations

Oral administration of the renal carcinogen, potassium bromate, specifically produces 8-hydroxydeoxyguanosine in rat target organ DNA

1987 • 343 citations

Damage to the Bases in DNA Induced by Hydrogen Peroxide and Ferric Ion Chelates

1989 • 332 citations

Free radicals and food additives

1992 • 318 citations

A rapid screening test to determine the antioxidant potencies of natural and synthetic antioxidants

1993 • 298 citations

Endogenous DNA adducts: Potential and paradox

1993 • 284 citations

Antimutagens and anticarcinogens: A survey of putative interceptor molecules

1990 • 268 citations

Free radicals in medicine

1993 • 252 citations

Possible mechanisms for the protective role of antioxidants in wine and plant foods : physiological mechanisms by which flavonoids, phenolics, and other phytochemicals in wine and plant foods prevent or ameliorate some common chronic diseases are discussed

1993 • 241 citations

Tolerance and safety of vitamin E: A toxicological position report

1992 • 237 citations

Free radicals in biological systems—a review orientated to inflammatory processes

1987 • 235 citations

Evaluation of the Antioxidant Actions of Ferulic Acid and Catechins

1993 • 223 citations

[5] Deoxyribose assay for detecting hydroxyl radicals

1994 • 211 citations

Chronic Granulomatous Disease

1987 • 204 citations

Garlic and its significance for the prevention of cancer in humans: a critical view

1993 • 203 citations

Lipid peroxidation and cancer

1993 • 195 citations

The beneficial and hazardous effects of simple phenolic compounds

1991 • 185 citations

Lipid-Soluble Antioxidants: Biochemistry and Clinical Applications

1992 • 184 citations

The cytotoxic and mutagenic properties of cholesterol oxidation products

1986 • 175 citations

Action of hypochlorous acid on the antioxidant protective enzymes superoxide dismutase, catalase and glutathione peroxidase

1987 • 170 citations

The biochemistry of methionine sulfoxide residues in proteins

1982 • 164 citations

Vanillin: More than a flavouring agent—a potent antioxidant

1989 • 146 citations

The antioxidant action of human extracellular fluids. Effect of human serum and its protein components on the inactivation of α1-antiproteinase by hypochlorous acid and by hydrogen peroxide

1987 • 142 citations

Invited Commentary:Superoxide, Iron, Vascular Endothelium and Reperfusion Injury

1989 • 128 citations

Generation of free radical intermediates from foreign compounds by neutrophil-derived oxidants.

1985 • 120 citations

Antioxidant and pro-oxidant activities of p-hydroxybenzyl alcohol and vanillin: Effects on free radicals, brain peroxidation and degradation of benzoate, deoxyribose, amino acids and DNA

1993 • 118 citations

An Evaluation of the Antioxidant and Potential Pro-Oxidant Properties of Food Additives and the Trolox C., Vitamin E and Probucol

1990 • 117 citations

Evidence for a role of taurine in the in vitro oxidative toxicity of neutrophils toward erythrocytes.

1985 • 116 citations

Quantitative high-performance liquid chromatography analysis of DNA oxidized in vitro and in vivo

1991 • 113 citations

Detection of DNA adducts by high-performance liquid chromatography with electrochemical detection

1989 • 113 citations

Differential antagonism by epipregnanolone of alphaxalone and pregnanolone potentiation of [3H]flunitrazepam binding suggests more than one class of binding site for steroids at GABAA receptors

1993 • 85 citations

Use of repair endonucleases to characterize DNA damage induced by reactive oxygen species in cellular and cell-free systems

1993 • 79 citations

Evaluation of the ability of the angiotensin-converting enzyme inhibitor captopril to scavenge reactive oxygen species

1991 • 77 citations

Enhancement of bleomycin—iron free radical damage to DNA by antioxidants and their inhibition of lipid peroxidation

1981 • 75 citations

Quantification of oxidative DNA modifications in mitochondria

1993 • 51 citations

Free radicals in tropical diseases

1994 • 45 citations

Method for the Analysis of Oxidized Nucleosides by Gas Chromatography Mass Spectrometry

1993 • 39 citations

Putative anticarcinogenic actions of carotenoids: nutritional implications

1993 • 35 citations

Oxidation of biologic molecules by ozone: the effect of pH.

1993 • 28 citations

Free radicals in medicine

1995 • 18 citations

Beta-Carotene: Helpful or Harmful?

1994 • 17 citations

Effect of DNA-repair enzymes on mutagenesis by oxygen free radicals

1993 • 13 citations