Induction of prostaglandin endoperoxide synthase‐2 in human monocytes associated with cyclo‐oxygenase‐dependent F2‐isoprostane formation

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

The Pathogenesis of Atherosclerosis — An Update

1986 • 4,951 citations

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.

1978 • 2,400 citations

A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.

1990 • 1,896 citations

Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain.

1994 • 1,579 citations

Human cyclooxygenase-2 cDNA.

1992 • 1,493 citations

Increase in Circulating Products of Lipid Peroxidation (F₂-Isoprostanes) in Smokers — Smoking as a Cause of Oxidative Damage

1995 • 1,343 citations

Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic.

1994 • 1,322 citations

Acetylation of prostaglandin synthase by aspirin.

1975 • 1,003 citations

cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase.

1992 • 838 citations

Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide.

1992 • 823 citations

Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids.

1992 • 742 citations

Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines.

1993 • 710 citations

Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects

1980 • 642 citations

Prostaglandin endoperoxide synthase: regulation of enzyme expression

1991 • 642 citations

Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chromosomal assignment

1991 • 580 citations

Different Intracellular Locations for Prostaglandin Endoperoxide H Synthase-1 and −2

1995 • 574 citations

Glomerular actions of a free radical-generated novel prostaglandin, 8-epi-prostaglandin F2 alpha, in the rat. Evidence for interaction with thromboxane A2 receptors.

1992 • 510 citations

Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases.

1994 • 500 citations

Lipocortin and the mechanism of action of the glucocorticoids

1988 • 499 citations

Dexamethasone inhibits mitogen induction of the TIS10 prostaglandin synthase/cyclooxygenase gene.

1992 • 412 citations

Immunological characterization of urinary 8-epi-prostaglandin F2 alpha excretion in man.

1995 • 340 citations

The measurement of free radical reactions in humans

1987 • 325 citations

Lipopolysaccharide induces prostaglandin H synthase-2 protein and mRNA in human alveolar macrophages and blood monocytes.

1994 • 310 citations

Free radical-induced generation of isoprostanes in vivo. Evidence for the formation of D-ring and E-ring isoprostanes.

1994 • 305 citations

Demonstration of an inducible cyclooxygenase in human endothelial cells using antibodies raised against the carboxyl-terminal region of the cyclooxygenase-2.

1993 • 293 citations

Biochemistry of prostaglandin endoperoxide H synthase-1 and synthase-2 and their differential susceptibility to nonsteroidal anti-inflammatory drugs.

1995 • 291 citations

Cylooxygenase-dependent Formation of the Isoprostane, 8-Epi Prostaglandin F2α

1995 • 262 citations

Evidence for the existence of F2-isoprostane receptors on rat vascular smooth muscle cells

1993 • 260 citations

Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGS-2 prostaglandin synthase gene in murine fibroblasts and macrophages.

1994 • 243 citations

The F2-isoprostane, 8-epi-prostaglandin F2α, a potent agonist of the vascular thromboxane/endoperoxide receptor, is a platelet thromboxane/endoperoxide receptor antagonist

1992 • 214 citations

Evidence that the F2-isoprostane, 8-epi-prostaglandin F2α, is formed in vivo

1994 • 166 citations

Lipopolysaccharide induces prostaglandin H synthase-2 in alveolar macrophages

1992 • 129 citations

Effects of a novel prostaglandin, 8-epi-PGF2 alpha, in rabbit lung in situ

1992 • 127 citations

Protein kinase A phosphorylation enhances sodium channel currents in Xenopus oocytes

1992 • 107 citations

Radioimmunoassay measurement of prostaglandins E2 and F2α in human urine

1979 • 99 citations

Platelet Activation and Lipid Peroxidation in Patients With Acute Ischemic Stroke

1997 • 99 citations

Evidence for episodic platelet activation in acute ischemic stroke.

1994 • 84 citations

Effects of the novel anti‐inflammatory compounds, N‐[2‐(cyclohexyloxy)‐4‐nitrophenyl] methanesulphonamide (NS‐398) and 5‐methanesulphonamido‐6‐(2, 4‐difluorothiophenyl)‐1‐indanone (L‐745, 337), on the cyclo‐oxygenase activity of human blood prostaglandin endoperoxide synthases

1995 • 83 citations

Preferential formation of 8-epi-prostaglandin f2α via the corresponding endoperoxide by a biomimetic cyclization

1984 • 69 citations

Antiaggregatory activity of 8-epi-prostaglandin F2 alpha and other F-series prostanoids and their binding to thromboxane A2/prostaglandin H2 receptors in human platelets.

1994 • 69 citations

Cyclooxygenase‐Dependent Formation of the Isoprostane 8‐EPI Prostaglandin F_2α^a

1994 • 66 citations

Identification of novel arachidonic acid metabolites formed by prostaglandin H synthase

1987 • 62 citations

The TCA cycle as an oxidative and synthetic pathway is suppressed with aging in jejunal epithelial cells

1994 • 30 citations

Characterization of human peripheral blood monocyte thromboxane A2 receptors.

1994 • 17 citations

Induction of prostaglandin endoperoxide synthase 2 in monocytes of human whole blood is associated with cyclooxygenase-dependent isoprostane formation

1995 • 7 citations

Cited By (0)

Loading...