Prostaglandin endoperoxide synthase: regulation of enzyme expression

The Physiology of Reproduction

1988 • 7,765 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

The eicosanoids and their biochemical mechanisms of action

1989 • 882 citations

Advances in Prostaglandin and Thromboxane Research

1976 • 840 citations

Stimulation of Endothelial Cell Prostacyclin Production by Thrombin, Trypsin, and the Ionophore A 23187

1978 • 715 citations

Human Leukemic Models of Myelomonocytic Development: A Review of the HL-60 and U937 Cell Lines

1985 • 649 citations

Interleukin-1 Mitogenic Activity for Fibroblasts and Smooth Muscle Cells Is Due to PDGF-AA

1989 • 648 citations

Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells.

1986 • 632 citations

Transcriptional autoregulation of the proto-oncogene fos

1988 • 630 citations

Prostaglandin endoperoxide synthase: structure and catalysis

1991 • 607 citations

Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription.

1986 • 548 citations

Prostaglandins modulate macrophage Ia expression

1982 • 545 citations

Preliminary Report: Findings from the Aspirin Component of the Ongoing Physicians' Health Study

1988 • 504 citations

Local and Systemic Factors in the Pathogenesis of Osteoporosis

1988 • 496 citations

Early changes in phosphatidylinositol and arachidonic acid metabolism in quiescent swiss 3T3 cells stimulated to divide by platelet-derived growth factor.

1981 • 492 citations

Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells.

1990 • 484 citations

Evidence for a peroxide-initiated free radical mechanism of prostaglandin biosynthesis.

1980 • 481 citations

Interleukin 1 stimulates fibroblasts to produce granulocyte-macrophage colony-stimulating activity and prostaglandin E2.

1986 • 458 citations

Bone and mineral research: Annual 2

1985 • 402 citations

Regulation of fibroblast cyclooxygenase synthesis by interleukin-1.

1988 • 401 citations

Clinical Implications of Prostaglandin and Thromboxane A₂Formation

1988 • 365 citations

Prostacyclin Synthesis Induced in Vascular Cells by Interleukin-1

1985 • 364 citations

Oxygenation of polyunsaturated fatty acids during prostaglandin biosynthesis by sheep vesicular glands

1972 • 362 citations

Translation is required for regulation of histone mRNA degradation

1987 • 345 citations

Autoregulated instability of β-tubulin mRNAs by recognition of the nascent amino terminus of βtubulin

1988 • 345 citations

Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme

1989 • 333 citations

Mononuclear cell modulation of connective tissue function: suppression of fibroblast growth by stimulation of endogenous prostaglandin production.

1980 • 282 citations

Initiation of human parturition. XII. Biosynthesis and metabolism of prostaglandins in human fetal membranes and uterine decidua.

1981 • 280 citations

Limitation of Excessive Myelopoiesis by the Intrinsic Modulation of Macrophage-Derived Prostaglandin E

1978 • 263 citations

Macrophage-mediated tumor cell killing: regulation of expression of cytolytic activity by prostaglandin E.

1981 • 238 citations

Initiation of human parturition

1981 • 224 citations

Human platelet-derived growth factor stimulates prostaglandin synthesis by activation and by rapid de novo synthesis of cyclooxygenase.

1985 • 219 citations

DNA binding specificity of steroid receptors

1989 • 212 citations

Changes in the synthesis and metabolism of prostaglandins by human fetal membranes and decidua at labor

1985 • 196 citations

Stimulation of prostaglandin synthesis by bradykinin and thrombin and their mechanisms of action on MC5-5 fibroblasts.

1976 • 196 citations

Biphasic Effects of Prostaglandin E₂on Bone Formation in Cultured Fetal Rat Calvariae: Interaction with Cortisol*

1990 • 189 citations

Stimulation of prostaglandin E2 synthesis in cloned osteoblastic cells of mouse (MC3T3-E1) by epidermal growth factor.

1986 • 167 citations

Interferon-gamma reduces macrophage-suppressive activity by inhibiting prostaglandin E2 release and inducing interleukin 1 production.

1984 • 166 citations

Prostaglandin Endoperoxide Synthase in Rat Ovarian Follicles: Content, Cellular Distribution, and Evidence for Hormonal Induction Preceding Ovulation*

1987 • 164 citations

Gene expression during the mammalian cell cycle

1986 • 161 citations

Concentrations of prostaglandin endoperoxide synthase and prostaglandin I2 synthase in the endothelium and smooth muscle of bovine aorta.

1983 • 148 citations

Macrophages release arachidonic acid, prostaglandin E2, and thromboxane in response to late complement components.

1984 • 144 citations

Exaggerated human vascular cell prostaglandin biosynthesis mediated by monocytes: role of monokines and interleukin 1.

1985 • 142 citations

Aspirin causes short-lived inhibition of bradykinin-stimulated prostacyclin production in man

1985 • 135 citations

Epidermal growth factor stimulation of prostaglandin E2 biosynthesis in amnion cells. Induction of prostaglandin H2 synthase.

1988 • 135 citations

Prostaglandin Output in Relation to Parturition by Cells Dispersed from Human Intrauterine Tissues*

1983 • 134 citations

Stimulation of de novo synthesis of prostaglandin G/H synthase in human endothelial cells by phorbol ester.

1988 • 132 citations

Regulation of Eicosanoid Production: Role of Phospholipases and Inhibitors

1987 • 129 citations

Regulation of Prostaglandin H Synthase mRNA Levels and Prostaglandin Biosynthesis by Platelet-derived Growth Factor

1989 • 124 citations

Ovulation rate and serum LH levels in rats treated with indomethacin or prostaglandin E2

1973 • 121 citations

Histamine stimulates prostacyclin synthesis in cultured human umbilical vein endothelial cells

1980 • 114 citations

Solubilization, purification, and characterization of a membrane-bound phospholipase A2 from the P388D1 macrophage-like cell line.

1988 • 114 citations

Inhibition Studies on the Membrane-associated Phospholipase A2 in vitro and Prostaglandin E2 Production in vivo of the Macrophage-like P388D1 Cell

1989 • 107 citations

Regulation of vascular prostaglandin synthesis by metabolites of arachidonic acid in perfused rabbit aorta.

1983 • 98 citations

Restoration of prostacyclin synthase in vascular smooth muscle cells after aspirin treatment: regulation by epidermal growth factor.

1985 • 98 citations

Histamine-stimulated and GTP-binding proteins-mediated phospholipase A2 activation in rabbit platelets.

1990 • 97 citations

Effect of Dexamethasone on Prostaglandin Synthesis and on Lipocortin Status in Human Endothelial Cells

1989 • 95 citations

The LDL receptor pathway delivers arachidonic acid for eicosanoid formation in cells stimulated by platelet-derived growth factor

1990 • 94 citations

Bradykinin and angiotensin II activation of arachidonic acid deacylation and prostaglandin E2 formation in rabbit kidney. Hormone-sensitive versus hormone-insensitive lipid pools of arachidonic acid.

1981 • 92 citations

Analysis of prostaglandin E2 effect on T lymphocyte activation. Abrogation of prostaglandin E2 inhibitory effect by the tumor promotor 12.0 tetradecanoyl phorbol-13 acetate.

1987 • 92 citations

Rapid Induction of Prostaglandin Endoperoxide Synthase in Rat Preovulatory Follicles by Luteinizing Hormone and cAMP is Blocked by Inhibitors of Transcription and Translation

1989 • 92 citations

Role of stimulation of arachidonic acid release in the proliferative response of 3T3 mouse fibroblasts to platelet‐derived growth factor

1982 • 91 citations

Alpha 1-adrenergic stimulation of arachidonic acid release and metabolism in a rat thyroid cell line. Mediation of cell replication by prostaglandin E2.

1986 • 89 citations

Kinetic analysis of the Ca2+-dependent, membrane-bound, macrophage phospholipase A2 and the effects of arachidonic acid.

1988 • 89 citations

Progesterone induces expression of endometrial messenger RNA encoding for cyclooxygenase (sheep)

1990 • 86 citations

Phorbol Ester Regulation of Rat Granulosa Cell Prostaglandin and Progesterone Accumulation*

1985 • 81 citations

Inhibition of Thromboxane A Synthesis in U937 Cells by Glucocorticoids

1989 • 79 citations

Enhanced translation and increased turnover of c-myc proteins occur during differentiation of murine erythroleukemia cells.

1990 • 79 citations

sn-1,2-Diacylglycerols and phorbol diesters stimulate thromboxane synthesis by de novo synthesis of prostaglandin H synthase in human promyelocytic leukemia cells.

1987 • 73 citations

The Prostaglandin Forming Cyclooxygenase of Ovine Uterus: Relationship to Luteal Function

1979 • 72 citations

Influence of natural and recombinant interleukin 2 on endothelial cell arachidonate metabolism. Induction of de novo synthesis of prostaglandin H synthase.

1988 • 71 citations

Inositol lipid turnover and compartmentation in canine trachealis smooth muscle

1989 • 64 citations

Effect of Time and Dose of Indomethacin on FoUicular Prostaglandins and Ovulation in the Rabbit*

1986 • 62 citations

Evidence for coordinate, selective regulation of eicosanoid synthesis in platelet-derived growth factor-stimulated 3T3 fibroblasts and in HL-60 cells induced to differentiate into macrophages or neutrophils.

1988 • 57 citations

Feedback regulation of colony-stimulating factor (CSF-1)-induced macrophage proliferation by endogenous E prostaglandins and interferon-alpha/beta.

1984 • 52 citations

Altered arachidonic acid metabolism during differentiation of the human monoblastoid cell line U937

1990 • 47 citations

Accumulation of lysophosphatidylinositol in RAW 264.7 macrophage tumor cells stimulated by lipid A precursors.

1987 • 45 citations

Epidermal growth factor-stimulated prostaglandin E2 production in human amnion cells: specificity and nonesterified arachidonic acid dependency

1987 • 43 citations

Fatty acid cyclooxygenase activity stimulated by transforming growth factor-β in mouse osteoblastic cells (MC3T3-E1)

1989 • 43 citations

Stimulation of Human Amnion Prostaglandin E₂Production by Activators of Protein Kinase-C*

1988 • 40 citations

Leukotriene induction of TxB2 in cultured bovine aortic endothelial cells

1984 • 39 citations

Prostaglandin E2 inhibits the activation of cloned T cell hybridomas.

1985 • 36 citations

Regulation of prostaglandin synthesis mediated by thrombin and b2 bradykinin receptors in a fibrosarcoma cell line

1982 • 35 citations

Reconstitution of an inactive antigen-specific T cell suppressor factor by incubation of the factor with prostaglandins.

1984 • 34 citations

[Prostaglandins in clinical practice].

1988 • 32 citations

The action of epidermal growth factor on human amnion prostaglandin E₂ output

1988 • 25 citations

Recovery of prostaglandin synthesis in rat glomerular mesangial cells after aspirin inhibition: Induction of cyclooxygenase activity by serum and epidermal growth factor

1990 • 13 citations

Deleted Work

1955 • 0 citations