Identification of residues in ornithine decarboxylase essential for enzymic activity and for rapid protein turnover

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

An Efficient mRNA‐Dependent Translation System from Reticulocyte Lysates

1976 • 3,994 citations

A rapid boiling method for the preparation of bacterial plasmids

1981 • 3,334 citations

POLYAMINES

1984 • 2,996 citations

High efficiency transformation of E.coli by high voltage electroporation

1988 • 2,789 citations

Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis

1986 • 2,566 citations

Polyamine metabolism and function

1982 • 1,649 citations

Recent advances in the biochemistry of polyamines in eukaryotes

1986 • 1,587 citations

Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy.

1988 • 1,533 citations

Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

1984 • 1,533 citations

Polyamines in rapid growth and cancer

1978 • 1,354 citations

Role of Polyamines in the Control of Cell Proliferation and Differentiation

1981 • 935 citations

Universality and Structure of the N-end Rule

1989 • 472 citations

Prevention of Rapid Intracellular Degradation of ODC by a Carboxyl-Terminal Truncation

1989 • 247 citations

Ornithine Decarboxylase as a Biological and Pharmacological Tool

1980 • 244 citations

Use of a chemically modified T7 DNA polymerase for manual and automated sequencing of supercoiled DNA.

1988 • 184 citations

Cloning and sequencing of the ornithine decarboxylase gene from Trypanosoma brucei. Implications for enzyme turnover and selective difluoromethylornithine inhibition.

1987 • 181 citations

Nucleotide sequence of murine ornithine decarboxylase mRNA.

1985 • 164 citations

Regulation of rat ornithine decarboxylase mRNA translation by its 5'-untranslated region.

1990 • 154 citations

Trypanosome ornithine decarboxylase is stable because it lacks sequences found in the carboxyl terminus of the mouse enzyme which target the latter for intracellular degradation.

1990 • 145 citations

Purification of ornithine decarboxylase from kidneys of androgen-treated mice

1982 • 144 citations

Degradation of Ornithine Decarboxylase in Reticulocyte Lysate Is ATP-dependent but Ubiquitin-independent

1989 • 139 citations

Regulation of enzyme levels by proteolysis: The role of pest regions

1988 • 139 citations

Role of antizyme in degradation of ornithine decarboxylase in HTC cells

1985 • 127 citations

Mouse ornithine decarboxylase. Complete amino acid sequence deduced from cDNA.

1985 • 116 citations

Inhibition of translation of mRNAs for ornithine decarboxylase and S-adenosylmethionine decarboxylase by polyamines.

1987 • 115 citations

Complete Amino Acid Sequence of Human Ornithine Decarboxylase Deduced from Complementary DNA

1987 • 99 citations

Rat Ornithine Decarboxylase Gene

1989 • 99 citations

Degradation of ornithine decarboxylase in mammalian cells is ATP dependent but ubiquitin independent

1989 • 93 citations

Site of pyruvate formation and processing of mammalian S-adenosylmethionine decarboxylase proenzyme

1989 • 91 citations

The gene and the primary structure of ornithine decarboxylase from Saccharomyces cerevisiae.

1987 • 85 citations

Influence of the 5'-untranslated region of ornithine decarboxylase mRNA and spermidine on ornithine decarboxylase synthesis.

1990 • 81 citations

Effect of 1,3-diaminopropane on ornithine decarboxylase enzyme protein in thioacetamide-treated rat liver

1983 • 78 citations

Spermidine mediates degradation of ornithine decarboxylase by a non‐lysosomal, ubiquitin‐independent mechanism

1987 • 69 citations

Control of ornithine decarboxylase activity in alpha-difluoromethylornithine-resistant L1210 cells by polyamines and synthetic analogues.

1988 • 67 citations

Molecular and genetic characterization of an ornithine decarboxylase-deficient Chinese hamster cell line.

1990 • 48 citations

Post-translational arginylation of ornithine decarboxylase from rat hepatocytes

1990 • 38 citations

Location of the phosphorylation site for casein kinase-2 within the amino acid sequence of ornithine decarboxylase

1987 • 31 citations

Involvement of antizyme in stabilization of ornithine decarboxylase caused by inhibitors of polyamine synthesis

1989 • 28 citations

Complementation of a polyamine-deficient Escherichia coli mutant by expression of mouse ornithine decarboxylase.

1987 • 27 citations

A rat monoclonal antibody which interacts with mammalian ornthine decarboxylase at an epitope involved in phosphorylation

1986 • 19 citations

Probable cloning artefacts previously interpreted as unusual leader sequences of rodent ornithine decarboxylase mRNAs — a cautionary tale

1988 • 15 citations

Phosphorylation of ornithine decarboxylase in intact erythroleukemia cells

1990 • 12 citations

Ornithine decarboxylase production in vitro by using mouse cDNA

1987 • 10 citations

Complementation of a Polyamine-Deficient Escherichia coli Mutant by Expression of Mouse Ornithine Decarboxylase

1987 • 9 citations

Interconversion of Tetrahymena pyriformis ornithine decar☐ylase from inactive to active form by phosphorylation

1989 • 5 citations