Molecular and genetic characterization of an ornithine decarboxylase-deficient Chinese hamster cell line.

Current protocols in molecular biology

1988 • 7,584 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

POLYAMINES

1984 • 2,996 citations

Recent advances in the biochemistry of polyamines in eukaryotes

1986 • 1,587 citations

The Inheritance of Epigenetic Defects

1987 • 1,058 citations

DNA methylation and gene activity

1988 • 904 citations

Reactivity of cytosine and thymine in single-base-pair mismatches with hydroxylamine and osmium tetroxide and its application to the study of mutations.

1988 • 636 citations

Detection of Single Base Substitutions by Ribonuclease Cleavage at Mismatches in RNA:DNA Duplexes

1985 • 538 citations

Parental legacy determines methylation and expression of an autosomal transgene: A molecular mechanism for parental imprinting

1987 • 478 citations

A method to detect and characterize point mutations in transcribed genes: amplification and overexpression of the mutant c-Ki-ras allele in human tumor cells.

1985 • 320 citations

Polyamines in Biomedical Research

1981 • 311 citations

Identification of Germline and Somatic Mutations Affecting the Retinoblastoma Gene

1988 • 270 citations

Prevention of Rapid Intracellular Degradation of ODC by a Carboxyl-Terminal Truncation

1989 • 247 citations

The regulation and function of ornithine decarboxylase and of the polyamines.

1979 • 247 citations

Differential methylation of hypoxanthine phosphoribosyltransferase genes on active and inactive human X chromosomes.

1984 • 226 citations

Molecular cloning and expression of the mouse ornithine decarboxylase gene.

1984 • 211 citations

The Polymerase Chain Reaction

1995 • 200 citations

Methylation of foreign DNA sequences in eukaryotic cells.

1980 • 190 citations

The Regulation and Function of Ornithine Decarboxylase and of the Polyamines* *In this article, “polyamines” include putrescine, spermidine, and spermine.

1979 • 175 citations

Inheritance of allelic blueprints for methylation patterns

1988 • 172 citations

Errors in the Polymerase Chain Reaction

1988 • 153 citations

Pattern of methylation of two genes coding for housekeeping functions.

1983 • 148 citations

An ornithine decarboxylase-deficient mutant of Chinese hamster ovary cells.

1982 • 136 citations

The rat P450IIE1 gene: complete intron and exon sequence, chromosome mapping, and correlation of developmental expression with specific 5' cytosine demethylation.

1988 • 134 citations

Scanning detection of mutations in human ornithine transcarbamoylase by chemical mismatch cleavage.

1989 • 129 citations

The inheritance of methylation patterns in vertebrates

1981 • 119 citations

Mouse ornithine decarboxylase. Complete amino acid sequence deduced from cDNA.

1985 • 116 citations

Effects of 5-azacytidine and its 2′-deoxyderivative on cell differentiation and DNA methylation

1985 • 116 citations

Polymerase Chain Reaction

2016 • 107 citations

Rat Ornithine Decarboxylase Gene

1989 • 99 citations

Variability of DNA methylation patterns during serial passage of human diploid fibroblasts

1982 • 97 citations

Ornithine Decarboxylase: Biology, Enzymology and Molecular Genetics

1990 • 95 citations

Isolation and characterization of the mouse ornithine decarboxylase gene.

1988 • 89 citations

Mouse ornithine decarboxylase gene: cloning, structure, and expression.

1988 • 77 citations

Two ornithine decarboxylase mRNA species in mouse kidney arise from size heterogeneity at their 3' termini.

1986 • 74 citations

Effect of in vitro DNA methylation on beta-globin gene expression.

1988 • 69 citations

Human ornithine decarboxylase sequences map to chromosome regions 2pter→p23 and 7cen→qter but are not coamplified with the NMYC oncogene

1986 • 67 citations

Cloning and nucleotide sequence of rat ornithine decarboxylase cDNA

1987 • 64 citations

Chinese hamster cells deficient in ornithine decarboxylase activity: Reversion by gene amplification and by azacytidine treatment

1985 • 61 citations

Complete sequence of three alpha-tubulin cDNAs in Chinese hamster ovary cells: each encodes a distinct alpha-tubulin isoprotein.

1986 • 49 citations

Human myeloma cells acquire resistance to difluoromethylornithine by amplification of ornithine decarboxylase gene

1987 • 46 citations

Amplification of ornithine decarboxylase gene in response to polyamine deprivation in Chinese hamster ovary cells.

1985 • 45 citations

A partial methylation profile for a CpG site is stably maintained in mammalian tissues and cultured cell lines

1989 • 44 citations

Chinese hamster ovary cells resistant to alpha-difluoromethylornithine are overproducers of ornithine decarboxylase.

1983 • 40 citations

Chinese hamster cells with a minichromosome containing the centromere region of human chromosome 1

1986 • 34 citations

The gene for ornithine decarboxylase is co-amplified in hydroxyurea-resistant hamster cells.

1987 • 32 citations

DNA methylation and genetic inactivation at thymidine kinase locus: Two different mechanisms for silencing autosomal genes

1988 • 26 citations

Nucleotide sequence of the human ornithine decarboxylase gene

1989 • 25 citations

DNA Methylation Patterns Associated with Asparagine Synthetase Expression in Asparagine-Overproducing and -Auxotrophic Cells

1989 • 25 citations

Nucleotide sequence of the Chinese hamster ornithine decarboxylase gene

1989 • 24 citations

A mutant of Chinese hamster ovary cells resistant toα-methyl- andα-difluoromethylornithine

1982 • 20 citations

Differential Methylation of the Ornithine Carbamoyl Transferase Gene on Active and Inactive Mouse X Chromosomes

1987 • 19 citations

Chromosomal assignment of amplified genes in hydroxyurea-resistant hamster cells

1987 • 18 citations

Deletion and hypermethylation of thymidine kinase gene in V79 Chinese hamster cells resistant to bromodeoxyuridine

1988 • 16 citations

Methylation of human ornithine decarboxylase gene before transfection abolishes its transient expression in Chinese hamster ovary cells

1989 • 16 citations

Identification of an X-linked member of theOdcgene family in the mouse

1988 • 11 citations

Association of an ornithine decarboxylase processed pseudogene with members of a Vκ immunoglobulin gene family provides a useful evolutionary clock

1987 • 8 citations