Transforming Growth Factor β Stimulates Fibroblast–Collagen Matrix Contraction by Different Mechanisms in Mechanically Loaded and Unloaded Matrices

Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

1993 • 2,169 citations

Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro.

1979 • 2,025 citations

The myofibroblast in wound healing and fibrocontractive diseases

2003 • 1,548 citations

COLLAGEN SUBSTRATA FOR STUDIES ON CELL BEHAVIOR

1972 • 1,530 citations

Alpha-Smooth Muscle Actin Expression Upregulates Fibroblast Contractile Activity

2001 • 1,207 citations

Fibroblasts, myofibroblasts, and wound contraction

1994 • 1,150 citations

Myofibroblasts. I. Paracrine cells important in health and disease

1999 • 908 citations

The Fibronectin Domain ED-A Is Crucial for Myofibroblastic Phenotype Induction by Transforming Growth Factor-β1

1998 • 801 citations

Bidirectional signaling between the cytoskeleton and integrins

1999 • 765 citations

TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop

1990 • 756 citations

Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair.

1993 • 706 citations

Mechanisms of Myofibroblast Activity and Phenotypic Modulation

1999 • 580 citations

Transforming growth factor beta stimulates collagen-matrix contraction by fibroblasts: implications for wound healing.

1988 • 559 citations

Induction of alpha-smooth muscle actin by transforming growth factor-beta 1 in quiescent human breast gland fibroblasts. Implications for myofibroblast generation in breast neoplasia.

1993 • 511 citations

Transforming Growth Factor-β1 Promotes the Morphological and Functional Differentiation of the Myofibroblast

2000 • 466 citations

The Compliance of Collagen Gels Regulates Transforming Growth Factor-β Induction of α-Smooth Muscle Actin in Fibroblasts

1999 • 462 citations

Isometric contraction by fibroblasts and endothelial cells in tissue culture: a quantitative study

1992 • 456 citations

Corneal stromal wound healing in refractive surgery: the role of myofibroblasts

1999 • 445 citations

Viscoelastic properties of human skin and processed dermis

2001 • 433 citations

Water transport revisited

1999 • 423 citations

Fibroblast–collagen-matrix contraction: growth-factor signalling and mechanical loading

2000 • 405 citations

Studies on the mechanism of hydrated collagen gel reorganization by human skin fibroblasts

1985 • 278 citations

Dependence of collagen remodelling on α‐smooth muscle actin expression by fibroblasts

1994 • 275 citations

Fibroblast contraction occurs on release of tension in attached collagen lattices: Dependency on an organized actin cytoskeleton and serum

1992 • 249 citations

Cell Mechanics Studied by a Reconstituted Model Tissue

2000 • 237 citations

Stress relaxation of contracted collagen gels: Disruption of actin filament bundles, release of cell surface fibronectin, and down-regulation of DNA and protein synthesis

1991 • 217 citations

Mechanical Properties of the Extracellular Matrix Influence Fibronectin Fibril Assembly in Vitro

1995 • 213 citations

Mechanisms and dynamics of mechanical strengthening in ligament-equivalent fibroblast-populated collagen matrices

1993 • 207 citations

Biochemical changes in the collagen of the palmar fascia in patients with Dupuytrenʼs disease.

1981 • 196 citations

Contraction of Hydrated Collagen Gels by Fibroblasts: Evidence for Two Mechanisms by which Collagen Fibrils are Stabilized

1987 • 151 citations

The mobile micro-architecture of dermal collagen: A bio-engineering study

1965 • 147 citations

V. TGF-β signaling pathways

2000 • 147 citations

Regulation of fibroblast-mediated collagen gel contraction by platelet-derived growth factor, interleukin-1 α and transforming growth factor-β1

1992 • 142 citations

Stimulation of Integrin-mediated Cell Contractility by Fibronectin Polymerization

2000 • 142 citations

Transforming Growth Factor-β Regulates Collagen Gel Contraction by Increasing α2β1 Integrin Expression in Osteogenic Cells

1995 • 115 citations

Fibroblasts from wounds of different stages of repair vary in their ability to contract a collagen gel in response to growth factors

1990 • 114 citations

Human Wound Healing Fibroblasts Have Greater Contractile Properties Than Dermal Fibroblasts

1994 • 108 citations

Is Smad3 a Major Player in Signal Transduction Pathways Leading to Fibrogenesis?

2001 • 106 citations

Transforming Growth Factor-β Initiates Wound Repair in Rat Liver through Induction of the EIIIA-Fibronectin Splice Isoform

2000 • 89 citations

Fibroblast Quiescence and the Disruption of ERK Signaling in Mechanically Unloaded Collagen Matrices

2000 • 86 citations

Condensation of Collagen Fibrils to the Direct Vicinity of Fibroblasts as a Cause of Gel Contraction1

1995 • 86 citations

Anin VitroForce Measurement Assay to Study the Early Mechanical Interaction between Corneal Fibroblasts and Collagen Matrix

1997 • 77 citations

In vitro models to study wound healing fibroblasts

1996 • 68 citations

Transforming Growth Factor-β1 Modulates Myofibroblastic Phenotype of Rat Palatal Fibroblastsin Vitro

1997 • 66 citations

Is Smad3 a Major Player in Signal Transduction Pathways Leading to Fibrogenesis?

2001 • 65 citations

Spatial organization of extracellular matrix and fibroblast activity: Effects of serum, transforming growth factor β, and fibronectin

1990 • 60 citations

Signal Transduction Pathways Activated During Fibroblast Contraction of Collagen Matrices

1999 • 33 citations

PERSISTENCE OF TGF-β1 INDUCTION OF INCREASED FIBROBLAST CONTRACTILITY

2001 • 28 citations

Regulation of matrix biosynthesis and degradation in systemic sclerosis

2000 • 26 citations

Transforming Growth Factor-β1 Stimulates Contraction of Human Glioblastoma Cell-Mediated Collagen Lattice through Enhanced α2 Integrin Expression

2000 • 25 citations

Contraction Potency of Hypertrophic Scar-derived Fibroblasts in a Connective Tissue Model

1995 • 21 citations

The Interaction of Cellular Fibronectin with Collagen During Fibroblast-Mediated Contraction of Collagen Gels

1999 • 8 citations

In vitro analysis of adhesion molecule expression and gel contraction of human granulation fibroblasts

1997 • 6 citations