The RTP Site Shared by the HIV-1 Tat Protein and the 11S Regulator Subunit α is Crucial for their Effects on Proteasome Function Including Antigen Processing

STRUCTURE AND FUNCTIONS OF THE 20S AND 26S PROTEASOMES

1996 • 2,408 citations

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

1997 • 2,291 citations

Structure of 20S proteasome from yeast at 2.4Å resolution

1997 • 2,211 citations

Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120

1995 • 983 citations

A gated channel into the proteasome core particle.

2000 • 791 citations

Antigen processing by the proteasome

2001 • 620 citations

Structural basis for the activation of 20S proteasomes by 11S regulators

2000 • 503 citations

Identification, purification, and characterization of a protein activator (PA28) of the 20 S proteasome (macropain).

1992 • 439 citations

The Axial Channel of the Proteasome Core Particle Is Gated by the Rpt2 ATPase and Controls Both Substrate Entry and Product Release

2001 • 413 citations

Purification of an 11 S regulator of the multicatalytic protease.

1992 • 384 citations

Hybrid Proteasomes

2000 • 342 citations

A role for the proteasome regulator PA28α in antigen presentation

1996 • 341 citations

Inhibition of Antigen-Induced Lymphocyte Proliferation by Tat Protein from HIV-1

1989 • 338 citations

Coordinated Dual Cleavages Induced by the Proteasome Regulator PA28 Lead to Dominant MHC Ligands

1996 • 287 citations

Regulatory subunit interactions of the 26S proteasome, a complex problem

2000 • 226 citations

Structural studies of HIV-1 tat protein

1995 • 191 citations

Structure of the proteasome activator REGα (PA28α)

1997 • 187 citations

Presentation of CMV immediate-early antigen to cytolytic T lymphocytes is selectively prevented by viral genes expressed in the early phase

1989 • 115 citations

HIV-1 Tat Inhibits the 20 S Proteasome and Its 11 S Regulator-mediated Activation

1997 • 111 citations

HIV-1 Tat: a polypeptide for all seasons

1998 • 109 citations

Differential Influence on Cytotoxic T Lymphocyte Epitope Presentation by Controlled Expression of Either Proteasome Immunosubunits or Pa28

2000 • 106 citations

The proteasome inhibitor PI31 competes with PA28 for binding to 20S proteasomes

1999 • 93 citations

Identification of an activation region in the proteasome activator REGα

1998 • 92 citations

Involvement of Dihydropyridine-sensitive Calcium Channels in Human Dendritic Cell Function

1998 • 77 citations

HIV-1 trans-activating (Tat) protein

1999 • 76 citations

Proteasomes: The World of Regulatory Proteolysis

2000 • 76 citations

Relative Functions of the α and β Subunits of the Proteasome Activator, PA28

1997 • 74 citations

Expression and subcellular localization of mouse 20S proteasome activator complex PA28

1997 • 67 citations

Characteristics of 26 S Proteases from Fission Yeast Mutants, which Arrest in Mitosis

1996 • 65 citations

Dictionary of interfaces in proteins (DIP). Data bank of complementary molecular surface patches 1 1Edited by R. Huber

1998 • 44 citations

The RGD-containing domain of exogenous HIV-1 Tat inhibits the engulfment of apoptotic bodies by dendritic cells

1997 • 42 citations

Highly stable oligomerization forms of HIV-1 Tat detected by monoclonal antibodies and requirement of monomeric forms for the transactivating function on the HIV-1 LTR

2000 • 37 citations

The proteasome activator 11 S REG or PA28: chimeras implicate carboxyl-terminal sequences in oligomerization and proteasome binding but not in the activation of specific proteasome catalytic subunits 1 1Edited by W. Baumeister

2000 • 25 citations

Conservation of substructures in proteins: interfaces of secondary structural elements in proteasomal subunits 1 1Edited by R. Huber

2000 • 19 citations

Homonyms and synonyms in the Dictionary of Interfaces in Proteins (DIP).

1999 • 13 citations