Wnt-5a and Wnt-7a are expressed in the developing chick limb bud in a manner suggesting roles in pattern formation along the proximodistal and dorsoventral axes

A series of normal stages in the development of the chick embryo

1951 • 12,226 citations

Cytoplasmic dot hybridization. Simple analysis of relative mRNA levels in multiple small cell or tissue samples.

1982 • 1,333 citations

The proximo‐distal sequence of origin of the parts of the chick wing and the role of the ectoderm

1948 • 1,101 citations

Organizing activity of wingless protein in Drosophila

1993 • 852 citations

Wnt genes

1992 • 799 citations

Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse

1992 • 676 citations

Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse

1991 • 646 citations

Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for Bone Morphogenetic Protein-2A (BMP-2A)

1990 • 616 citations

Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo

1987 • 578 citations

Responses of embryonic xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm

1992 • 486 citations

Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development.

1990 • 458 citations

Distribution of the wingless gene product in drosophila embryos: A protein involved in cell-cell communication

1989 • 452 citations

Retinoids, homeoboxes, and growth factors: Toward molecular models for limb development

1991 • 410 citations

Expression of the homeobox Hox-4 genes and the specification of position in chick wing development

1991 • 394 citations

Distal-less encodes a homoeodomain protein required for limb development in Drosophila

1989 • 389 citations

Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderminducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis

1991 • 373 citations

Homeobox gene expression correlated with the bifurcation process of limb cartilage development

1991 • 317 citations

Targeted misexpression of Hox-4.6 in the avian limb bud causes apparent homeotic transformations

1992 • 307 citations

The proto-oncogene int-1 encodes a secreted protein associated with the extracellular matrix.

1990 • 280 citations

Expression of two members of the Wnt family during mouse development--restricted temporal and spatial patterns in the developing neural tube.

1991 • 279 citations

A wingless -Dependent Polar Coordinate System in Drosophila Imaginal Discs

1993 • 266 citations

Secretion and movement of wingless protein in the epidermis of the Drosophila embryo

1991 • 244 citations

Collagen gene expression during limb cartilage differentiation.

1986 • 238 citations

Proximal-distal pattern formation in Drosophila : cell autonomous requirement for Distal-less gene activity in limb development

1989 • 234 citations

Involvement of the Chox-4 chicken homeobox genes in determination of anteroposterior axial polarity during limb development

1991 • 223 citations

Secreted int-1 protein is associated with the cell surface.

1990 • 215 citations

The mouse Dlx-2 (Tes-1) gene is expressed in spatially restricted domains of the forebrain, face and limbs in midgestation mouse embryos

1993 • 209 citations

Overlapping Expression of Xwnt-3A and Xwnt-1 in Neural Tissue of Xenopus laevis Embryos

1993 • 202 citations

Replication-competent retroviral vectors encoding alkaline phosphatase reveal spatial restriction of viral gene expression/transduction in the chick embryo.

1993 • 187 citations

Hybridization of Oligo(dT) to RNA on nitrocellulose

1987 • 184 citations

Position-dependent expression of two related homeobox genes in developing vertebrate limbs

1991 • 181 citations

Ectodermal-mesodermal interactions in the growth of limb buds in the chick embryo: Constancy and temporal limits of the ectodermal induction

1972 • 163 citations

Ectodermal control of the dorsoventral axis in the leg bud of the chick embryo,

1974 • 159 citations

Expression of the murine Dlx-1 homeobox gene during facial, ocular and limb development

1992 • 158 citations

The apical ectodermal ridge regulates Hox-7 and Hox-8 gene expression in developing chick limb buds.

1991 • 152 citations

The Mouse Wnt-1 Gene Can Act Via a Paracrine Mechanism in Transformation of Mammary Epithelial Cells

1992 • 138 citations

The Wnt family of developmental regulators

1992 • 121 citations

Chicken homeobox gene Msx-1: structure, expression in limb buds and effect of retinoic acid

1991 • 120 citations

The mouse Wnt-1 gene can act via a paracrine mechanism in transformation of mammary epithelial cells.

1992 • 109 citations

Expression of the chicken homeobox-containing gene GHox-8 during embryonic chick limb development

1991 • 108 citations

Repating developmental expression of G-Hox 7, a novel homeobox-containing gene in the chicken

1991 • 99 citations

Localization of HstI transcripts to the apical ectodermal ridge in the mouse embryo

1992 • 91 citations

Altered expression of the chicken homeobox-containing genes GHox-7 and GHox-8 in the limb buds of limbless mutant chick embryos

1991 • 91 citations

Analysis of Xwnt-4 in embryos of Xenopus laevis: A Wnt family member expressed in the brain and floor plate

1992 • 88 citations

Distribution of insulin-like growth factor peptides in the developing chick embryo

1990 • 86 citations

Temporal and spatial analysis of cartilage proteoglycan core protein gene expression during limb development by in situ hybridization

1988 • 78 citations

Insulin-like growth factor I and II and insulin-like growth factor binding protein-2 RNAs are expressed in adjacent tissues within rat embryonic and fetal limbs

1992 • 68 citations

Apical ridge dependent and independent mesodermal domains of GHox-7 and GHox-8 expression in chick limb buds

1992 • 66 citations

Isolation and expression of two novel Wnt/wingless gene homologues in Drosophila

1992 • 63 citations

Correlation of expression of Wnt-1 in developing limbs with abnormalities in growth and skeletal patterning

1993 • 55 citations

Analisi sperimentale dello sviluppo dell'ala nell'embrione di pollo

1958 • 51 citations

GHox-7: A chicken homeobox-containing gene expressed in a fashion consistent with a role in patterning events during embryonic chick limb development

1992 • 51 citations

Cloning and developmental expression in Xenopus laevis of seven additional members of the Wnt family.

1992 • 51 citations

Cloning and characterization of a novel Drosophila Wnt gene, Dwnt-5, a putative downstream target of the homeobox gene Distal-less

1992 • 47 citations

Mammalian limb bud development: In situ fate maps of early hindlimb buds

1989 • 43 citations

Differential expression of two MSH-related homeobox genes Chox-7 and Chox-8 during chick limb development

1992 • 42 citations

The Wnt family of developmental regulators

1992 • 37 citations

The expression pattern of the chicken homeobox-containing gene GHox-7 in developing polydactylous limb buds suggests its involvement in apical ectodermal ridge-directed outgrowth of limb mesoderm and in programmed cell death

1993 • 36 citations

Role of the chicken homeobox-containing genes GHox-4.6 and GHox-8 in the specification of positional identities during the development of normal and polydactylous chick limb buds

1992 • 33 citations

Gene transfer of lacZ into avian neural tube and neural crest cells by retroviral infection of grafted embryonic tissues

1993 • 18 citations

Ectoderm from Various Regions of the Developing Chick Limb Bud Differentially Regulates the Expression of the Chicken Homeobox-Containing Genes GHox-7 and GHox-8 by Limb Mesenchymal Cells

1993 • 17 citations