Cloning and characterization of a novel Drosophila Wnt gene, Dwnt-5, a putative downstream target of the homeobox gene Distal-less

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

1989 • 2,555 citations

The embryonic development of Drosophila melanogaster

1938 • 2,188 citations

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

1982 • 1,790 citations

The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

1990 • 1,531 citations

The molecular genetics of embryonic pattern formation in Drosophila

1988 • 1,048 citations

Comparison of the consensus sequence flanking translational start sites inDrosophilaand vertebrates

1987 • 966 citations

The Drosophila homology of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless

1987 • 906 citations

Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development

1990 • 896 citations

Wnt genes

1992 • 799 citations

Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

1988 • 745 citations

The engrailed locus of drosophila: Structural analysis of an embryonic transcript

1985 • 735 citations

Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing center

1991 • 651 citations

Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15

1984 • 609 citations

Functional cDNA libraries from Drosophila embryos

1988 • 604 citations

Sequence, structure, and codon preference of theDrosophilaribosomal protein 49 gene

1984 • 523 citations

Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis

1989 • 518 citations

Injected Wnt RNA induces a complete body axis in Xenopus embryos

1991 • 501 citations

Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development.

1990 • 458 citations

Distribution of the wingless gene product in drosophila embryos: A protein involved in cell-cell communication

1989 • 452 citations

Molecular cloning of sequences from wingless , a segment polarity gene in Drosophila : the spatial distribution of a transcript in embryos

1987 • 437 citations

Distal-less encodes a homoeodomain protein required for limb development in Drosophila

1989 • 389 citations

Two-tiered regulation of spatially patterned engrailed gene expression during Drosophila embryogenesis

1988 • 383 citations

Role of segment polarity genes in the definition and maintenance of cell states in the Drosophila embryo

1988 • 381 citations

Spatial expression of the Drosophila segment polarity gene armadillo is posttranscriptionally regulated by wingless

1990 • 374 citations

Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderminducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis

1991 • 373 citations

Induction across germ layers in Drosophila mediated by a genetic cascade

1990 • 342 citations

The embryonic development of Drosophila melanogaster

1986 • 339 citations

The proto-oncogene int-1 encodes a secreted protein associated with the extracellular matrix.

1990 • 280 citations

Expression of two members of the Wnt family during mouse development--restricted temporal and spatial patterns in the developing neural tube.

1991 • 279 citations

A mouse gene related to Distal-less shows a restricted expression in the developing forebrain

1991 • 273 citations

Homeotic genes regulate the spatial expression of putative growth factors in the visceral mesoderm of Drosophila embryos

1990 • 265 citations

The Drosophila PS2 antigen is an invertebrate integrin that, like the fibronectin receptor, becomes localized to muscle attachments

1987 • 263 citations

Secretion and movement of wingless protein in the epidermis of the Drosophila embryo

1991 • 244 citations

Swaying is a mutant allele of the proto-oncogene Wnt-1

1991 • 242 citations

The role of segment polarity genes during Drosophila neurogenesis.

1989 • 235 citations

Proximal-distal pattern formation in Drosophila : cell autonomous requirement for Distal-less gene activity in limb development

1989 • 234 citations

Embryonic and imaginal requirements for wingless, a segment-polarity gene in Drosophila

1988 • 228 citations

Secreted int-1 protein is associated with the cell surface.

1990 • 215 citations

Specification of limb development in the Drosophila embryo by positional cues from segmentation genes

1990 • 211 citations

Segmental organisation of the head in the embryo of Drosophila melanogaster

1986 • 198 citations

The development of wingless, a homeotic mutation of Drosophila

1977 • 185 citations

Expression of the murine Dlx-1 homeobox gene during facial, ocular and limb development

1992 • 158 citations

Autonomous requirements for the segment polarity gene armadillo during Drosophila embryogenesis

1987 • 145 citations

The Mouse Wnt-1 Gene Can Act Via a Paracrine Mechanism in Transformation of Mammary Epithelial Cells

1992 • 138 citations

Genomic structure and restricted neural expression of the zebrafish wnt-1 (int-1) gene.

1991 • 129 citations

Diversification of the Wnt gene family on the ancestral lineage of vertebrates.

1992 • 127 citations

Identification of genes from pattern formation, tyrosine kinase, and potassium channel families by DNA amplification.

1989 • 123 citations

The int genes in mammary tumorigenesis and in normal development

1988 • 117 citations

Nucleotide sequence and expression in vitro of cDNA derived from mRNA of int-1, a provirally activated mouse mammary oncogene.

1985 • 110 citations

The mouse Wnt-1 gene can act via a paracrine mechanism in transformation of mammary epithelial cells.

1992 • 109 citations

The nucleotide sequence of the human int-1 mammary oncogene; evolutionary conservation of coding and non-coding sequences.

1985 • 106 citations

Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless.

1988 • 95 citations

Segment polarity genes and cell patterning within the Drosophila body segment

1991 • 81 citations

Isolation of cDNAs partially encoding four Xenopus - proteins and characterization of their transient expression during embryonic development

1991 • 77 citations

Isolation of theXenopusbomolog ofint-1/winglessand expression during neurula stages of early development

1989 • 73 citations

Nucleotide sequence, chromosomal localization and developmental expression of the mouse int-1-related gene

1989 • 70 citations

Early developmental subdivisions of the wing disk in Drosophila

1977 • 47 citations

Genetic and developmental analysis of polytene section 17 of the X chromosome of Drosophila melanogaster.

1992 • 36 citations

Cloning of segment polarity gene homologues from the unsegmented brachiopod Terebratulina retusa (Linnaeus)

1991 • 13 citations

Nucleotide sequence of a cDNA encoding Wnt-1 of the Mexican axolotlAmbystoma mexicanum

1991 • 7 citations

Nucleotide sequence of a cDNA encoding Wnt-1 of the Mexican axolotlAmbystoma mexicanum

1990 • 5 citations

Molecular genetics of the hairy locus of Drosophila melanogaster

1986 • 3 citations

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