Soluble CD40 ligand can replace the normal T cell-derived CD40 ligand signal to B cells in T cell-dependent activation.

A new member of the immunoglobulin superfamily—CTLA-4

1987 • 1,214 citations

A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells.

1992 • 818 citations

A human beta-actin expression vector system directs high-level accumulation of antisense transcripts.

1987 • 767 citations

Activation of human B cells mediated through two distinct cell surface differentiation antigens, Bp35 and Bp50.

1986 • 439 citations

Activated human T cells express a ligand for the human B cell‐associated antigen CD40 which participates in T cell‐dependent activation of B lymphocytes

1992 • 323 citations

Use of Monoclonal Anti-mouse Immunoglobulin to Detect Mouse Antibodies

1981 • 252 citations

The use of hybrid hybridomas to target human cytotoxic T lymphocytes

1987 • 199 citations

T cell-dependent activation of B cell proliferation and differentiation by immobilized monoclonal antibodies to CD3.

1988 • 144 citations

Resting B lymphocytes can be triggered directly through the CDw40 (Bp50) antigen. A comparison with IL-4-mediated signaling.

1988 • 136 citations

Two Lyt-2 polypeptides arise from a single gene by alternative splicing patterns of mRNA

1985 • 135 citations

Stimulation of B-cell proliferation by membrane-associated molecules from activated T cells.

1988 • 98 citations

Myeloma based expression system for production of large mammalian proteins

1991 • 97 citations

Differential increase of an alternatively polyadenylated mRNA species of murine CD40 upon B lymphocyte activation.

1992 • 63 citations

The hinge region of the CD8α chain: structure, antigenicity, and utility in expression of immunoglobulin superfamily domains

1992 • 61 citations

Activation of human B lymphocytes: frequency of antigen‐specific B cells triggered by alloreactive or by antigen‐specific T cell clones

1983 • 56 citations