Identification of a Novel Inhibitor of Nuclear Factor-κB, RelA-associated Inhibitor

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis

1986 • 2,566 citations

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.

1995 • 1,739 citations

An analysis of vertebrate mRNA sequences: intimations of translational control.

1991 • 1,655 citations

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway.

1995 • 1,296 citations

Complementation Cloning of NEMO, a Component of the IκB Kinase Complex Essential for NF-κB Activation

1998 • 1,070 citations

Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli.

1995 • 1,010 citations

The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors.

1993 • 819 citations

IκB-β regulates the persistent response in a biphasic activation of NF-κB

1995 • 780 citations

Regulation of NF-κB by Cyclin-Dependent Kinases Associated with the p300 Coactivator

1997 • 725 citations

DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide

1991 • 604 citations

NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules.

1997 • 576 citations

Structure of the p53 Tumor Suppressor Bound to the Ankyrin and SH3 Domains of 53BP2

1996 • 569 citations

Structure of NF-κB p50 homodimer bound to a κB site

1995 • 564 citations

Structure of the NF-κB p50 homodimer bound to DNA

1995 • 525 citations

Oxidoreductive regulation of nuclear factor kappa B. Involvement of a cellular reducing catalyst thioredoxin

1993 • 490 citations

NF-κB as a Frequent Target for Immunosuppressive and Anti-Inflammatory Molecules**This article was accepted for publication on 27 September 1996.

1997 • 472 citations

Isolation of a rel -related Human cDNAThat Potentially Encodes the 65-kD Subunit of NF-κB

1991 • 448 citations

Two cellular proteins that bind to wild-type but not mutant p53.

1994 • 423 citations

I kappa B epsilon, a novel member of the Ikappa B family, controls RelA and cRel NF-kappa B activity

1997 • 394 citations

Role of Unphosphorylated, Newly Synthesized IκBβ in Persistent Activation of NF-κB

1996 • 228 citations

Interaction of Stat6 and NF-κB: Direct Association and Synergistic Activation of Interleukin-4-Induced Transcription

1998 • 202 citations

Autoregulation of the NF-kappa B transactivator RelA(p65) by multiple cytoplasmic inhibitors containing ankyrinmotifs.

1994 • 187 citations

The p53-Binding Protein 53BP2 Also Interacts with Bcl2 and Impedes Cell Cycle Progression at G₂/M

1996 • 159 citations

Inhibition of the DNA‐binding activity of NF‐κB by gold compounds in vitro

1995 • 155 citations

The Interferon-Inducible p202 Protein as a Modulator of Transcription: Inhibition of NF-κB, c-Fos, and c-Jun Activities

1996 • 152 citations

IκBα Functions through Direct Contacts with the Nuclear Localization Signals and the DNA Binding Sequences of NF-κB

1998 • 151 citations

Nuclear Localization of IκBα Is Mediated by the Second Ankyrin Repeat: the IκBα Ankyrin Repeats Define a Novel Class of cis-Acting Nuclear Import Sequences

1998 • 142 citations

Induction of cytokines and ICAM-1 by proinflammatory cytokines in primary rheumatoid synovial fibroblasts and inhibition by N-acetyl-L-cysteine and aspirin

1996 • 121 citations

Augmentation of Human Immunodeficiency Virus Type 1 Gene Expression by Tumor Necrosis Factor α

1989 • 110 citations

TAFII105 mediates activation of anti-apoptotic genes by NF-kappa B

1998 • 81 citations

Regulation of NF-κB and Disease Control: Identification of a Novel Serine Kinase and Thioredoxin as Effectors for Signal Transduction Pathway for NF-κB Activation

1997 • 75 citations

Distinct residues of human p53 implicated in binding to DNA, simian virus 40 large T antigen, 53BP1, and 53BP2.

1994 • 60 citations

Sequence Analysis of theERCC2Gene Regions in Human, Mouse, and Hamster Reveals Three Linked Genes

1996 • 55 citations

Transcriptional activation from the long-terminal repeat of human immunodeficiency virus in Vitro

1990 • 53 citations

Proteolytic processing of nuclear factor κB by calpain in vitro

1996 • 50 citations

The Signal Response of IκBα Is Regulated by Transferable N- and C-Terminal Domains

1997 • 46 citations

Inhibition of Human Immunodeficiency Virus Type 1 Replication by a Bioavailable Serine/Threonine Kinase Inhibitor, Fasudil Hydrochloride

1998 • 39 citations

Assignment of the IκB-β gene NFKBIB to human chromosome band 19q13.1 by in situ hybridization

1998 • 8 citations