Effect of high dose aspirin on coronary hemodynamics during pacing-induced myocardial ischemia

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

1976 • 3,613 citations

Protective Effects of Aspirin against Acute Myocardial Infarction and Death in Men with Unstable Angina

1983 • 1,740 citations

Measurement of Coronary Sinus Blood Flow by Continuous Thermodilution in Man

1971 • 973 citations

Inhibition of platelet prostaglandin synthetase by oral aspirin.

1978 • 552 citations

A Platelet-Inhibitor-Drug Trial in Coronary-Artery Bypass Operations

1982 • 550 citations

Increased Prostacyclin Biosynthesis in Patients with Severe Atherosclerosis and Platelet Activation

1984 • 510 citations

Coronary Arterial Smooth Muscle Contraction by a Substance Released from Platelets: Evidence That It Is Thromboxane A ₂

1976 • 504 citations

Differential Inhibition by Aspirin of Vascular and Platelet Prostaglandin Synthesis in Atherosclerotic Patients

1983 • 460 citations

Recovery of Endothelial Cell Prostacyclin Production after Inhibition by Low Doses of Aspirin

1979 • 310 citations

Prostacyclin is not a circulating hormone in man

1982 • 290 citations

DIFFERENTIAL INHIBITION OF PROSTACYCLIN PRODUCTION AND PLATELET AGGREGATION BY ASPIRIN

1979 • 284 citations

Absorption Kinetics of Aspirin in Man follow Oral Administration of an Aqueous Solution

1972 • 269 citations

Coronary Tone Modulation: Formation and Actions of Prostaglandins, Endoperoxides, and Thromboxanes

1977 • 244 citations

Thromboxane release during pacing-induced angina pectoris: possible vasoconstrictor influence on the coronary vasculature.

1980 • 224 citations

Coronary Vasoconstrictor Effect of Indomethacin in Patients with Coronary-Artery Disease

1981 • 206 citations

Elevation of thromboxane B2 levels in patients with classic and variant angina Pectoris.

1981 • 206 citations

DIFFERENTIAL INHIBITION BY LOW-DOSE ASPIRIN OF HUMAN VENOUS PROSTACYCLIN SYNTHESIS AND PLATELET THROMBOXANE SYNTHESIS

1981 • 200 citations

BLUE EYEDROPS

1974 • 167 citations

Prostaglandins and the cardiovascular system.

1983 • 113 citations

Platelet aggregation in aortic and coronary venous blood in patients with and without coronary disease. 3. Role of tachycardia stress and propranolol.

1978 • 113 citations

Biochemical Aspects of Prostaglandins and Thromboxanes

1977 • 107 citations

Thromboxane A2 and prostaglandin H2: Potent stimulators of the swine coronary artery

1976 • 84 citations

THE DISCOVERY OF PROSTACYCLIN – – – A FRESH INSIGHT INTO ARACHIDONIC ACID METABOLISM

1977 • 77 citations

Very low levels of 6-keto-prostaglandin F1 alpha in human plasma.

1982 • 69 citations

Effect of aspirin in large doses on attacks of variant angina

1983 • 65 citations

Reduced prostacyclin production in patients with different manifestations of ischemic heart disease

1982 • 56 citations

Aspirin therapy in angina pectoris: Effects on platelet aggregation, exercise tolerance, and electrocardiographic manifestations of ischemia

1976 • 51 citations

Specific and sensitive method for the determination of aspirin and salicylic acid in plasma using reversed-phase high-performance liquid chromatography

1980 • 45 citations

Influence of blood sampling site and technique on thromboxane concentrations in patients with ischemic heart disease

1982 • 27 citations

Effects of provocation on transcardiac thromboxane in patients with coronary artery disease

1983 • 24 citations

Relative effects of aspirin on platelet aggregation and prostaglandin-mediated coronary vasodilatation in the dog.

1980 • 17 citations

Significance of thromboxane A2 in myocardial ischemia in patients with coronary artery disease.

1980 • 9 citations

Effect of atrial pacing on intracoronary thromboxane production in coronary artery disease

1983 • 5 citations

[Prostacyclin--inhibitory effect on thrombocyte aggregation on the vascular wall in vivo?].

1978 • 5 citations

Effect of Platelet Suppressant Treatment with Dipyridamole and Aspirin on Exercise Performance and Platelet Survival Time in Coronary Disease

1981 • 4 citations

The release of thromboxane during atrial pacing and the haemodynamic and metabolic effects of its inhibition by dazoxiben

1982 • 3 citations