Aging affect the anti-tumor potential of dendritic cell vaccination, but it can be overcome by co-stimulation with anti-OX40 or anti-4-1BB☆

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Impaired antigen-induced CD8+ T cell clonal expansion in aging is due to defects in antigen presenting cell function

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The effect of age on the expression of Interleukin-2

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Peripheral T cell tolerance occurs early during spontaneous prostate cancer development and can be rescued by dendritic cell immunization

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The CD8⁺ T cell repertoire against Her‐2/neu antigens in neu transgenic mice is of low avidity with antitumor activity

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Molecular and cellular basis of immunosenescence

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Efficacy of cancer gene therapy in aging: adenocarcinoma cells engineered to release IL-2 are rejected but do not induce tumor specific immune memory in old mice

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Aged Mice Develop Protective Antitumor Immune Responses with Appropriate Costimulation

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Age‐related decrement in cytotoxic T lymphocyte (CTL) activity is associated with decreased levels of mRNA encoded by two CTL‐associated serine esterase genes and the perforin gene in mice

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Low effectiveness of DNA vaccination against HER-2/neu in ageing

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