Three classes of dopamine receptor (D-2, D-3, D-4) identified by binding studies with 3H-apomorphine and 3H-domperidone

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

Multiple receptors for dopamine

1979 • 3,739 citations

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

1980 • 1,750 citations

Lesion of striatal neurons with kainic acid provides a model for Huntington's chorea

1976 • 1,247 citations

The Rat Brain. A Stereotaxic Atlas

1964 • 1,002 citations

Neurotransmitter receptor binding

1978 • 822 citations

Dopamine Receptor Binding Enhancement Accompanies Lesion-Induced Behavioral Supersensitivity

1977 • 716 citations

Brain receptors for antipsychotic drugs and dopamine: direct binding assays.

1975 • 695 citations

Serotonergic component of neuroleptic receptors

1978 • 621 citations

Spiperone: A ligand of choice for neuroleptic receptors

1978 • 541 citations

Regional concentrations of noradrenaline and dopamine in rat brain

1976 • 518 citations

Properties of [3H]haloperidol and [3H]dopamine binding associated with dopamine receptors in calf brain membranes.

1976 • 480 citations

Drug‐Induced Changes in the Release of ³H‐Monoamines from Field Stimulated Rat Brain Slices

1971 • 453 citations

Pharmacological estimation of drug-receptor dissociation constants. Statistical evaluation. I. Agonists.

1971 • 435 citations

Evidence for dopamine receptors mediating sedation in the mouse brain

1976 • 421 citations

The Solution of the Four-Color-Map Problem

1977 • 412 citations

Dopamine receptors localised on cerebral cortical afferents to rat corpus striatum

1978 • 401 citations

Dopamine receptor binding: Differentiation of agonist and antagonist states with 3H-dopamine and 3H-haloperidol

1975 • 390 citations

Dopaminergic neurons: An in vivo system for measuring drug interactions with presynaptic receptors

1976 • 350 citations

Climbing behavior induced by apomorphine in mice: a simple test for the study of dopamine receptors in striatum

1976 • 341 citations

Atlas stéréotaxique du diencéphale du rat blanc

1966 • 327 citations

Catecholamine receptor agonists

1976 • 318 citations

Biochemical demonstration of dopaminergic receptors in rat and human brain using [3H]spiroperidol

1977 • 298 citations

Effect of dopamine receptor agonists and antagonists on release of dopamine in the rabbit caudate nucleus in vitro

1978 • 242 citations

Nigrostriatal lesions enhance striatal 3H-apomorphine and 3H-spiroperidol binding

1979 • 237 citations

Modulation of receptor mechanisms in the CNS: Hyper-and hyposensitivity to catecholamines

1978 • 221 citations

Long-term changes in the sensitivity of pre- and postsynaptic dopamine receptors in mouse striatum evidenced by behavioural and biochemical studies

1977 • 216 citations

Direct evidence for presynaptic and postsynaptic dopamine receptors in brain

1978 • 210 citations

3H-spiroperidol labels serotonin receptors in rat cerebral cortex and hippocampus

1978 • 206 citations

Effect of guanine nucleotides on striatal dopamine receptors

1978 • 186 citations

The role of presynaptic receptors in the release and synthesis of 3H-dopamine by slices of rat striatum

1976 • 166 citations

Dopamine receptors in human and calf brains, using [3H]apomorphine and an antipsychotic drug.

1976 • 161 citations

Comparison of the effects of neuroleptic drugs on pre- and postsynaptic dopaminergic mechanisms in the rat striatum.

1976 • 160 citations

AN ADAPTATION OF THE PUSH‐PULL CANNULA METHOD TO STUDY THE IN VIVO RELEASE OF [³H]DOPAMINE SYNTHESIZED FROM [³H]TYROSINE IN THE CAT CAUDATE NUCLEUS: EFFECTS OF VARIOUS PHYSICAL AND PHARMACOLOGICAL TREATMENTS

1977 • 146 citations

Guanine nucleotides distinguish between two dopamine receptors

1979 • 144 citations

3H-Domperidone: A selective ligand for dopamine receptors

1979 • 128 citations

Pharmacology and Neurochemistry of Apomorphine

1978 • 128 citations

Dopamine receptors in the retina may all be linked to adenylate cyclase

1979 • 125 citations

Rapid and dissociated changes in sensitivities of different dopamine receptors in mouse brain

1975 • 123 citations

Dopamine receptor binding: Specificity, localization and regulation by ions and guanyl nucleotides

1978 • 119 citations

Dopamine receptor binding regulated by guanine nucleotides.

1979 • 111 citations

Dopamine autoreceptors: pharmacology, function and comparison with post-synaptic dopamine receptors.

1979 • 111 citations

Antagonistic effects of apomorphine and haloperidol on rat striatal synaptosomal tyrosine hydroxylase

1974 • 105 citations

3H-apomorphine labels both dopamine postsynaptic receptors and autoreceptors

1980 • 102 citations

Dopamine autoreceptors: pharmacology, function and comparison with post-synaptic dopamine receptors.

1979 • 102 citations

Species variations in dopamine receptor binding

1979 • 94 citations

Multiple receptors for brain dopamine.

1978 • 86 citations

Antagonism by haloperidol of locomotor depression induced by small doses of apomorphine

1977 • 80 citations

Increase in tyrosine hydroxylase activity in the locus coeruleus of the rat brain after contralateral lesioning

1975 • 74 citations

Selective labeling of different dopamine receptors by a new agonist 3H-ligand: 3H-N-propylnorapomorphine

1979 • 71 citations

Effect of extracellular dopamine on the release of dopamine in the rabbit caudate nucleus: Evidence for a dopaminergic feedback inhibition

1979 • 66 citations

Quantitative assessment of heterogeneous 3H-spiperone binding to rat neostriatum and frontal cortex

1980 • 61 citations

Characterization of 3H-domperidone binding on striatal dopamine receptors

1978 • 47 citations

Antagonism by sulpiride of three apomorphine-induced effects in rodents

1976 • 45 citations

High affinity dopamine receptors (D3) in rat brain.

1979 • 42 citations

The measurement of glutamate decarboxylase activity in brain tissues by a simple microradiometric method

1975 • 39 citations

MULTIPLE DOPAMINE BINDING SITES: SUBCELLULAR LOCALIZATION AND BIOCHEMICAL CHARACTERIZATION¹

1979 • 34 citations

"Second messengers" in the brain.

1977 • 31 citations

Sedative action of low doses of dopaminergic agents.

1977 • 27 citations

“Second Messengers” in the Brain

1977 • 27 citations

Dopamine receptor binding for agonists and antagonists in thermal exposed membranes

1979 • 26 citations

Effect of kainic acid on striatal dopamine receptors

1980 • 24 citations

Unitary dopaminergic receptor composed of cooperatively linked agonist and antagonist sub-unit binding sites.

1979 • 23 citations

Endogenous components of the striatum confer dopamine-sensitivity upon adenylate cyclase activity: The role of endogenous guanyl nucleotides

1980 • 19 citations

Ligand binding to dopamine-receptors: Analysis & interpretation

1978 • 12 citations

Mechanism of Thermal Inactivation of Freeze-Dried Ecbo Virus Serotype VG (5) 27

1977 • 6 citations

DENDRITIC RELEASE OF DOPAMINE: ITS ROLE IN THE CONTROL OF NIGROSTRIATAL DOPAMINERGIC NEURONES

1979 • 4 citations

3H-DOMPERIDONE AND 3H-PIMOZIDE : MORE SPECIFIC LIGANDS FOR DOPAMINE RECEPTORS STUDIED IN VITRO AND IN VIVO

1979 • 2 citations

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