Identification and Characterization of Multiple Forms of Bovine Brain N-Myristoyltransferase

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system.

1988 • 1,241 citations

Myristylation and palmitylation of Src family members: The fats of the matter

1994 • 694 citations

Myristoylation-dependent replication and assembly of human immunodeficiency virus 1.

1990 • 634 citations

GENETIC AND BIOCHEMICAL STUDIES OF PROTEIN N-MYRISTOYLATION

1994 • 403 citations

Antisera of designed specificity for subunits of guanine nucleotide-binding regulatory proteins.

1986 • 380 citations

Protein N-myristoylation

1991 • 289 citations

Identification of human immunodeficiency virus type 1 Gag protein domains essential to membrane binding and particle assembly

1994 • 251 citations

Purification and characterization of yeast myristoyl CoA:protein N-myristoyltransferase.

1987 • 241 citations

Rous sarcoma virus transforming protein lacking myristic acid phosphorylates known polypeptide substrates without inducing transformation

1986 • 223 citations

Fatty acylated proteins as components of intracellular signaling pathways

1990 • 202 citations

SDS—PAGE strongly overestimates the molecular masses of the neurofilament proteins

1984 • 189 citations

Interaction of acyl-CoA binding protein (ACBP) on processes for which acyl-CoA is a substrate, product or inhibitor

1993 • 186 citations

Recent studies of ribonuclease P.

1993 • 177 citations

Targeted gene replacement demonstrates that myristoyl-CoA: protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans.

1994 • 169 citations

Characterization of ligand binding to acyl-CoA-binding protein

1993 • 163 citations

Kinetic and structural evidence for a sequential ordered Bi Bi mechanism of catalysis by Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase

1991 • 144 citations

Protein fatty acid acylation: enzymatic synthesis of an N-myristoylglycyl peptide.

1986 • 123 citations

Comparison of myristoyl-CoA:protein N-myristoyltransferases from three pathogenic fungi: Cryptococcus neoformans, Histoplasma capsulatum, and Candida albicans.

1994 • 122 citations

Genetic studies reveal that myristoylCoA:protein N‐myristoyltransferase is an essential enzyme in Candida albicans

1995 • 120 citations

Mutations of human myristoyl-CoA:protein N-myristoyltransferase cause temperature-sensitive myristic acid auxotrophy in Saccharomyces cerevisiae.

1992 • 115 citations

Developments in Cancer Chemotherapy

2019 • 112 citations

A comparative analysis of the kinetic mechanism and peptide substrate specificity of human and Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase

1993 • 107 citations

Myristoylation is important at multiple stages in poliovirus assembly

1991 • 105 citations

The substrate specificity of Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase. Analysis of myristic acid analogs containing oxygen, sulfur, double bonds, triple bonds, and/or an aromatic residue

1991 • 94 citations

Replication of human immunodeficiency virus 1 and Moloney murine leukemia virus is inhibited by different heteroatom-containing analogs of myristic acid.

1989 • 92 citations

4-oxatetradecanoic acid is fungicidal for Cryptococcus neoformans and inhibits replication of human immunodeficiency virus I.

1992 • 79 citations

Substrate specificity of Saccharomyces cerevisiae myristoyl-CoA: protein N-myristoyltransferase. Analysis of fatty acid analogs containing carbonyl groups, nitrogen heteroatoms, and nitrogen heterocycles in an in vitro enzyme assay and subsequent identification of inhibitors of human immunodeficiency virus I replication.

1992 • 76 citations

Comparison of the acyl chain specificities of human myristoyl-CoA synthetase and human myristoyl-CoA:protein N-myristoyltransferase.

1993 • 71 citations

Incorporation of 12-methoxydodecanoate into the human immunodeficiency virus 1 gag polyprotein precursor inhibits its proteolytic processing and virus production in a chronically infected human lymphoid cell line.

1991 • 70 citations

Structural and functional studies of Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase produced in Escherichia coli. Evidence for an acyl-enzyme intermediate.

1990 • 68 citations

Analyzing the substrate specificity of Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase by co-expressing it with mammalian G protein alpha subunits in Escherichia coli

1991 • 67 citations

N-myristoylation of p60src. Identification of a myristoyl-CoA:glycylpeptide N-myristoyltransferase in rat tissues

1988 • 60 citations

S-(2-oxopentadecyl)-CoA, a nonhydrolyzable analog of myristoyl-CoA, is a potent inhibitor of myristoyl-CoA: protein N-myristoyltransferase

1989 • 56 citations

Studies of the catalytic activities and substrate specificities of Saccharomyces cerevisiae myristoyl-coenzyme A: protein N-myristoyltransferase deletion mutants and human/yeast Nmt chimeras in Escherichia coli and S. cerevisiae.

1992 • 50 citations

Myristoyl‐CoA: protein N‐myristoyltransferase activity in cancer cells

1993 • 48 citations

Purification and partial sequencing of myristoyl-CoA:protein N-myristoyltransferase from bovine brain

1993 • 39 citations

Analysis of the compartmentalization of myristoyl-CoA:protein N-myristoyltransferase in Saccharomyces cerevisiae.

1992 • 39 citations

Chromatography —A laboratory handbook of chromatographic and electrophoretic methods

1976 • 34 citations

Genetic and biochemical studies of a mutant Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase, nmt72pLeu99–>Pro, that produces temperature-sensitive myristic acid auxotrophy.

1993 • 34 citations

Inhibition of varicella-zoster virus replication by an inhibitor of protein myristoylation

1993 • 32 citations

Demonstration of multiple forms of bovine brain myristoyl CoA: protein N-myristoyl transferase

1992 • 32 citations

Transverse-plane topography of long-chain acyl-CoA synthetase in the mitochondrial outer membrane.

1990 • 31 citations

Purification and properties of bovine spleen N-myristoyl-CoA protein:N-myristoyltransferase.

1994 • 31 citations

Use of photoactivatable peptide substrates of Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase (Nmt1p) to characterize a myristoyl-CoA-Nmt1p-peptide ternary complex and to provide evidence for an ordered reaction mechanism.

1993 • 31 citations

Characterization of a polyhistidine‐tagged form of human myristoyl‐CoA:protein N‐myristoyltransferase produced in Escherichia coli

1994 • 31 citations

Mechanisms of action of NIP71 on N-myristoyltransferase activity

1994 • 15 citations

Gel electrophoresis of proteins

1992 • 15 citations

Synthesis and characterization of inhibitors of myristoyl-CoA:Protein N-myristoyltransferase

1991 • 14 citations