Identification of human immunodeficiency virus type 1 Gag protein domains essential to membrane binding and particle assembly

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase.

1986 • 2,118 citations

Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1.

1989 • 831 citations

THE BIOLOGY AND ENZYMOLOGY OF EUKARYOTIC PROTEIN ACYLATION

1988 • 787 citations

Effect of mutations affecting the p6 gag protein on human immunodeficiency virus particle release.

1991 • 644 citations

Myristoylation-dependent replication and assembly of human immunodeficiency virus 1.

1990 • 634 citations

[16] Isolation of subcellular organelles

1990 • 563 citations

Complete Nucleotide Sequences of Functional Clones of the AIDS Virus

1987 • 348 citations

The matrix protein of human immunodeficiency virus type 1 is required for incorporation of viral envelope protein into mature virions

1992 • 320 citations

Myristylation site in Pr65gag is essential for virus particle formation by Moloney murine leukemia virus.

1986 • 300 citations

Myristylation is required for intracellular transport but not for assembly of D-type retrovirus capsids

1987 • 241 citations

Human immunodeficiency virus-like particles produced by a vaccinia virus expression vector.

1989 • 223 citations

A large deletion in the matrix domain of the human immunodeficiency virus gag gene redirects virus particle assembly from the plasma membrane to the endoplasmic reticulum

1993 • 199 citations

Human immunodeficiency virus envelope protein determines the site of virus release in polarized epithelial cells.

1991 • 181 citations

A single amino acid substitution within the matrix protein of a type D retrovirus converts its morphogenesis to that of a type C retrovirus

1990 • 160 citations

Specific and saturable binding of pp60v-src to plasma membranes: Evidence for a myristyl-src receptor

1989 • 137 citations

Production of human immunodeficiency virus (HIV)-like particles from cells infected with recombinant vaccinia viruses carrying the gag gene of HIV

1990 • 125 citations

Suppression of retroviral MA deletions by the amino-terminal membrane-binding domain of p60src

1991 • 114 citations

Immunological and Chemical Analysis of P6, the Carboxyl-Terminal Fragment of HIV P15

1987 • 104 citations

Processing of p60v-src to its myristylated membrane-bound form.

1985 • 102 citations

Amino acid substitutions within the matrix protein of type D retroviruses affect assembly, transport and membrane association of a capsid.

1991 • 92 citations

Expression and extracellular release of human immunodeficiency virus type 1 Gag precursors by recombinant baculovirus-infected cells

1992 • 81 citations

Membrane association of the myristoylated alanine-rich C kinase substrate (MARCKS) protein appears to involve myristate-dependent binding in the absence of a myristoyl protein receptor.

1992 • 60 citations

Myristate-protein interactions in poliovirus: interactions of VP4 threonine 28 contribute to the structural conformation of assembly intermediates and the stability of assembled virions

1992 • 48 citations

Processing of p60^v-src to Its Myristylated Membrane-Bound Form

1985 • 40 citations

Characterization of monoclonal antibodies against the human immunodeficiency virus matrix protein, p17gag: identification of epitopes exposed at the surfaces of infected cells

1991 • 39 citations

Phosphorylation of HIV-1 gag proteins by protein kinase C.

1993 • 38 citations

Poorly expressed endogenous ecotropic provirus of DBA/2 mice encodes a mutant Pr65gag protein that is not myristylated

1988 • 36 citations

Vpx of simian immunodeficiency virus is localized primarily outside the virus core in mature virions

1993 • 36 citations

Identification and characterization of human immunodeficiency virus type 1 gag-pol fusion protein in transfected mammalian cells

1991 • 32 citations

Matrix protein of Akv murine leukemia virus: genetic mapping of regions essential for particle formation

1992 • 21 citations

Analysis of Retroviral Assembly Using a Vaccinia/T7-Polymerase Complementation System

1993 • 13 citations