An N-ethylmaleimide-sensitive cytosolic factor necessary for nuclear protein import: requirement in signal-mediated binding to the nuclear pore.

A short amino acid sequence able to specify nuclear location

1984 • 2,529 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

1988 • 1,504 citations

Sequence requirements for nuclear location of simian virus 40 large-T antigen

1984 • 1,278 citations

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor

1988 • 1,200 citations

Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor.

1987 • 999 citations

Protein translocation across the endoplasmic reticulum

1984 • 825 citations

Formation in Vitro of Sperm Pronuclei and Mitotic Chromosomes Induced by Amphibian Ooplasmic Components

1983 • 630 citations

Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs

1986 • 622 citations

A role for the nuclear envelope in controlling DNA replication within the cell cycle

1988 • 605 citations

Construction and characterization of an SV40 mutant defective in nuclear transport of T antigen

1984 • 566 citations

Nuclear protein migration involves two steps: Rapid binding at the nuclear envelope followed by slower translocation through nuclear pores

1988 • 551 citations

Nuclear reconstitution in vitro: Stages of assembly around protein-free DNA

1987 • 550 citations

Protein Import into the Cell Nucleus

1986 • 544 citations

Nuclear import can be separated into distinct steps in vitro: Nuclear pore binding and translocation

1988 • 535 citations

Purification of an N-ethylmaleimide-sensitive protein catalyzing vesicular transport.

1988 • 519 citations

Inhibition of in vitro nuclear transport by a lectin that binds to nuclear pores.

1987 • 510 citations

Movement of a karyophilic protein through the nuclear pores of oocytes.

1984 • 510 citations

Purification of a membrane-associated protein complex required for protein translocation across the endoplasmic reticulum.

1980 • 502 citations

The nuclear lamins

1986 • 488 citations

Myosin Structure and Function in Cell Motility

1987 • 479 citations

Synthetic peptides as nuclear localization signals

1986 • 472 citations

Definition of regions in human c-myc that are involved in transformation and nuclear localization.

1987 • 457 citations

Sequence requirements for synthetic peptide-mediated translocation to the nucleus.

1989 • 413 citations

Induction of nuclear transport with a synthetic peptide homologous to the SV40 T antigen transport signal

1986 • 394 citations

Role of an N-ethylmaleimide-sensitive transport component in promoting fusion of transport vesicles with cisternae of the Golgi stack

1988 • 389 citations

The Saccharomyces cerevisiae SEC14 gene encodes a cytosolic factor that is required for transport of secretory proteins from the yeast Golgi complex.

1989 • 381 citations

70-kD heat shock-related protein is one of at least two distinct cytosolic factors stimulating protein import into mitochondria.

1988 • 380 citations

Intracellular Transport Using Microtubule-Based Motors

1987 • 356 citations

Nuclear location signals in polyoma virus large-T

1986 • 351 citations

Disassembly of the nucleus in mitotic extracts: Membrane vesicularization, lamin disassembly, and chromosome condensation are independent processes

1987 • 349 citations

THE NUCLEUS: STRUCTURE, FUNCTION, AND DYNAMICS

1987 • 333 citations

Ia binding ligands and cAMP stimulate nuclear translocation of PKC in B lymphocytes

1987 • 321 citations

The nuclear envelope and the architecture of the nuclear periphery.

1981 • 320 citations

Possible role for fatty acyl-coenzyme A in intracellular protein transport

1987 • 302 citations

Identification of the Human c-myc Protein Nuclear Translocation Signal

1988 • 299 citations

The nucleoplasmin nuclear location sequence is larger and more complex than that of SV-40 large T antigen.

1988 • 296 citations

Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization.

1984 • 284 citations

Nucleoplasmin cDNA sequence reveals polyglutamic acid tracts and a cluster of sequences homologous to putative nuclear localization signals.

1987 • 263 citations

Roles of cytosol and cytoplasmic particles in nuclear envelope assembly and sperm pronuclear formation in cell-free preparations from amphibian eggs.

1984 • 254 citations

Each of the activities of signal recognition particle (SRP) is contained within a distinct domain: Analysis of biochemical mutants of SRP

1988 • 248 citations

Structure, biochemistry, and functions of the nuclear envelope.

1974 • 237 citations

Assembly in vitro of nuclei active in nuclear protein transport: ATP is required for nucleoplasmin accumulation.

1986 • 235 citations

Reversible inhibition of protein import into the nucleus by wheat germ agglutinin injected into cultured cells

1987 • 233 citations

Identification of the sequence responsible for the nuclear accumulation of the influenza virus nucleoprotein in Xenopus oocytes

1985 • 220 citations

Identification of specific binding proteins for a nuclear location sequence

1989 • 219 citations

Mutations in the nuclear lamin proteins resulting in their aberrant assembly in the cytoplasm.

1988 • 217 citations

In vitro transport of a fluorescent nuclear protein and exclusion of non-nuclear proteins.

1986 • 211 citations

A DNA-binding factor specific for xenobiotic responsive elements of P-450c gene exists as a cryptic form in cytoplasm: its possible translocation to nucleus.

1988 • 198 citations

Amino acid sequences that determine the nuclear localization of yeast histone 2B.

1987 • 194 citations

The nuclear migration signal of Xenopus laevis nucleoplasmin.

1987 • 176 citations

Use of peptide tagging to detect proteins expressed from cloned genes: deletion mapping functional domains of Drosophila hsp 70.

1984 • 175 citations

Nuclear transport kinetics depend on phosphorylation-site-containing sequences flanking the karyophilic signal of the Simian virus 40 T-antigen.

1989 • 175 citations

Pentapeptide nuclear localization signal in adenovirus E1a.

1987 • 165 citations

Identification of a nuclear localization signal of a yeast ribosomal protein.

1985 • 162 citations

A trypsin-sensitive receptor on membrane vesicles is required for nuclear envelope formation in vitro.

1988 • 148 citations

Inhibition of nuclear accumulation of karyophilic proteins in living cells by microinjection of the lectin wheat germ agglutinin

1988 • 146 citations

The ultrastructure of the nuclear envelope of amphibian oocytes: a reinvestigation I. The mature oocyte

1970 • 141 citations

On the universality of nuclear pore complex structure

1970 • 134 citations

Identification of domains involved in nuclear uptake and histone binding of protein N1 of Xenopus laevis.

1988 • 132 citations

A domain of SV40 capsid polypeptide VP1 that specifies migration into the cell nucleus.

1986 • 120 citations

Nuclei act as independent and integrated units of replication in a Xenopus cell-free DNA replication system.

1987 • 119 citations

Definition of Regions in Human c-myc that are Involved in Transformation and Nuclear Localization

1987 • 106 citations

Identification of four nuclear transport signal-binding proteins that interact with diverse transport signals.

1989 • 101 citations

The nuclear location signal

1985 • 92 citations

The control of DNA replication in a cell-free extract that recapitulates a basic cell cycle in vitro

1988 • 91 citations

Amino Acid Sequences That Determine the Nuclear Localization of Yeast Histone 2B

1987 • 86 citations

Antibodies to Asp-Asp-Glu-Asp Can Inhibit Transport of Nuclear Proteins into the Nucleus

1988 • 84 citations

Effect of basic and nonbasic amino acid substitutions on transport induced by simian virus 40 T-antigen synthetic peptide nuclear transport signals.

1988 • 83 citations

Protein translocation across the yeast microsomal membrane is stimulated by a soluble factor.

1986 • 80 citations

A first exon-encoded domain of E1A sufficient for posttranslational modification, nuclear-localization, and induction of adenovirus E3 promoter expression in Xenopus oocytes.

1985 • 49 citations

Signal-dependent translocation of simian virus 40 large-T antigen into rat liver nuclei in a cell-free system.

1987 • 49 citations

Identification of Four Nuclear Transport Signal-Binding Proteins That Interact with Diverse Transport Signals

1989 • 45 citations

ATP-dependent association of nuclear proteins with isolated rat liver nuclei.

1988 • 31 citations

Posttranscriptional regulation and assembly into ribosomes of a Saccharomyces cerevisiae ribosomal protein-beta-galactosidase fusion.

1985 • 31 citations

Effect of Basic and Nonbasic Amino Acid Substitutions on Transport Induced by Simian Virus 40 T-Antigen Synthetic Peptide Nuclear Transport Signals

1988 • 31 citations

Signal-Dependent Translocation of Simian Virus 40 Large-T Antigen into Rat Liver Nuclei in a Cell-Free System

1987 • 16 citations

Posttranscriptional Regulation and Assembly into Ribosomes of a Saccharomyces cerevisiae Ribosomal Protein–β-Galactosidase Fusion

1985 • 7 citations