Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

AMoRe: an automated package for molecular replacement

1994 • 4,990 citations

Improved Fourier coefficients for maps using phases from partial structures with errors

1986 • 1,897 citations

Evaluation of single-crystal X-ray diffraction data from a position-sensitive detector

1988 • 1,516 citations

The Ras-RasGAP Complex: Structural Basis for GTPase Activation and Its Loss in Oncogenic Ras Mutants

1997 • 1,482 citations

Selenomethionyl proteins produced for analysis by multiwavelength anomalous diffraction (MAD): a vehicle for direct determination of three-dimensional structure.

1990 • 1,013 citations

Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis

1994 • 823 citations

The 2.2 Å crystal structure of transducin-α complexed with GTPγS

1993 • 788 citations

Structure of RGS4 Bound to AlF4−-Activated Giα1: Stabilization of the Transition State for GTP Hydrolysis

1997 • 770 citations

GTPase mechanism of Gproteins from the 1.7-Å crystal structure of transducin α - GDP AIF−4

1994 • 564 citations

Structure at 1.65 Å of RhoA and its GTPase-activating protein in complex with a transition-state analogue

1997 • 487 citations

Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85.

1994 • 392 citations

The GTP binding motif: variations on a theme

1996 • 262 citations

Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP

1997 • 252 citations

Ras-catalyzed hydrolysis of GTP: a new perspective from model studies.

1996 • 205 citations

Formation of a Transition-State Analog of the Ras GTPase Reaction by Ras·GDP, Tetrafluoroaluminate, and GTPase-Activating Proteins

1996 • 201 citations

The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue

1997 • 192 citations

Characterization of rhoGAP. A GTPase-activating protein for rho-related small GTPases.

1994 • 159 citations

Cloning and expression of a human CDC42 GTPase-activating protein reveals a functional SH3-binding domain.

1993 • 123 citations

Definition of the Switch Surface in the Solution Structure of Cdc42Hs^,

1997 • 82 citations

Biochemical Studies of the Mechanism of Action of the Cdc42-GTPase-activating Protein

1998 • 44 citations

Fluoride Activation of the Rho Family GTP-binding Protein Cdc42Hs

1998 • 42 citations