Structure at 1.65 Å of RhoA and its GTPase-activating protein in complex with a transition-state analogue

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway

1995 • 1,653 citations

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1995 • 1,499 citations

The Ras-RasGAP Complex: Structural Basis for GTPase Activation and Its Loss in Oncogenic Ras Mutants

1997 • 1,482 citations

Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis.

1990 • 1,077 citations

An essential role for Rac in Ras transformation

1995 • 895 citations

The Cellular Functions of Small GTP-Binding Proteins

1990 • 881 citations

Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis

1994 • 823 citations

RIBBONS 2.0

1991 • 814 citations

Structure of RGS4 Bound to AlF4−-Activated Giα1: Stabilization of the Transition State for GTP Hydrolysis

1997 • 770 citations

Microinjection of recombinant p21rho induces rapid changes in cell morphology.

1990 • 720 citations

X-ray Structures of the Myosin Motor Domain of Dictyostelium discoideum Complexed with MgADP.cntdot.BeFx and MgADP.cntdot.AlF4-

1995 • 610 citations

GTPase mechanism of Gproteins from the 1.7-Å crystal structure of transducin α - GDP AIF−4

1994 • 564 citations

Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1

1997 • 531 citations

Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine

1997 • 492 citations

Rho: theme and variations

1996 • 290 citations

Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP

1997 • 252 citations

GAPs for rho-related GTPases

1994 • 248 citations

Ras-catalyzed hydrolysis of GTP: a new perspective from model studies.

1996 • 205 citations

The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue

1997 • 192 citations

Synergistic effects of substrate-induced conformational changes in phosphoglycerate kinase activation

1997 • 190 citations

Role of Glutamine-61 in the Hydrolysis of GTP by p21H-ras: An Experimental and Theoretical Study

1994 • 141 citations

The structure of the GTPase-activating domain from p50rhoGAP

1997 • 122 citations

AlF ₃ mimics the transition state of protein phosphorylation in the crystal structure of nucleoside diphosphate kinase and MgADP

1997 • 117 citations

Structures of Active Conformations of UMP Kinase from Dictyostelium discoideum Suggest Phosphoryl Transfer Is Associative

1997 • 97 citations

Gasp: not just another oncogene

1989 • 29 citations

Structural and Mechanistic Aspects of the GTPase Reaction of H-ras p21

1993 • 14 citations

Deleted Work

1955 • 0 citations