THUMP – a predicted RNA-binding domain shared by 4-thiouridine, pseudouridine synthases and RNA methylases

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1997 • 71,835 citations

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

Prediction of Protein Secondary Structure at Better than 70% Accuracy

1993 • 2,958 citations

Bacterial stress responses.

2011 • 905 citations

Bacterial Stress Responses

2000 • 866 citations

Summary: the modified nucleosides of RNA

1994 • 517 citations

Comparative Genomics of the Archaea (Euryarchaeota): Evolution of Conserved Protein Families, the Stable Core, and the Variable Shell

1999 • 270 citations

Prediction of the Archaeal Exosome and Its Connections with the Proteasome and the Translation and Transcription Machineries by a Comparative-Genomic Approach

2001 • 251 citations

Pseudouridine Synthases: Four Families of Enzymes Containing a Putative Uridine-Binding Motif Also Conserved in dUTPases and dCTP Deaminases

1996 • 225 citations

The iscS Gene in Escherichia coli Is Required for the Biosynthesis of 4-Thiouridine, Thiamin, and NAD

2000 • 190 citations

Novel Predicted RNA-Binding Domains Associated with the Translation Machinery

1999 • 182 citations

Hybrid Fold Recognition: Combining Sequence Derived Properties with Evolutionary Information

1999 • 182 citations

Evidence That ThiI, an Enzyme Shared between Thiamin and 4-Thiouridine Biosynthesis, May Be a Sulfurtransferase That Proceeds through a Persulfide Intermediate

2000 • 165 citations

Evidence for the Transfer of Sulfane Sulfur from IscS to ThiI during the in Vitro Biosynthesis of 4-Thiouridine inEscherichia coli tRNA

2000 • 139 citations

Identification of new RNA modifying enzymes by iterative genome search using known modifying enzymes as probes

1996 • 130 citations

A P‐loop‐like motif in a widespread ATP pyrophosphatase domain: Implications for the evolution of sequence motifs and enzyme activity

1994 • 122 citations

Identification of a gene involved in the generation of 4-thiouridine in tRNA

1998 • 113 citations

Eukaryotic ribosomal RNA: the recent excitement in the nucleotide modification problem

1997 • 83 citations

A model of Cdc25 phosphatase catalytic domain and Cdk-interaction surface based on the presence of a rhodanese homology domain

1998 • 82 citations

The pseudouridine residues of ribosomal RNA

1995 • 79 citations

A New Heat Shock Protein That Binds Nucleic Acids

1999 • 59 citations

Using genomic information to investigate the function of ThiI, an enzyme shared between thiamin and 4‐thiouridine biosynthesis

1999 • 52 citations