Autophagy regulates lipid metabolism

Prevalence of the Metabolic Syndrome Among US Adults

2002 • 6,823 citations

Autophagy fights disease through cellular self-digestion

2008 • 6,047 citations

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

2005 • 2,207 citations

[19] Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

1983 • 1,639 citations

Extensive Involvement of Autophagy in Alzheimer Disease: An Immuno-Electron Microscopy Study

2005 • 1,435 citations

Dissection of Autophagosome Formation Using Apg5-Deficient Mouse Embryonic Stem Cells

2001 • 1,310 citations

Dual Roles for Glucokinase in Glucose Homeostasis as Determined by Liver and Pancreatic β Cell-specific Gene Knock-outs Using Cre Recombinase

1999 • 1,284 citations

Lipid droplets: a unified view of a dynamic organelle

2006 • 1,114 citations

Autophagy Counterbalances Endoplasmic Reticulum Expansion during the Unfolded Protein Response

2006 • 967 citations

Endoplasmic Reticulum Stress Triggers Autophagy

2006 • 923 citations

The Phosphatidylinositol 3‐Kinase Inhibitors Wortmannin and LY294002 Inhibit Autophagy in Isolated Rat Hepatocytes

1997 • 828 citations

Studies on the mechanisms of autophagy: formation of the autophagic vacuole.

1990 • 789 citations

Autophagy and Aging: The Importance of Maintaining "Clean" Cells

2005 • 773 citations

Protein Turnover Via Autophagy: Implications for Metabolism

2007 • 766 citations

CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

2000 • 746 citations

Perilipin A Increases Triacylglycerol Storage by Decreasing the Rate of Triacylglycerol Hydrolysis

2000 • 428 citations

Piecemeal Microautophagy of Nucleus inSaccharomyces cerevisiae

2003 • 415 citations

Studies on the mechanisms of autophagy: maturation of the autophagic vacuole.

1990 • 352 citations

Proteolytic and lipolytic responses to starvation

2006 • 309 citations

Lipolysis: pathway under construction

2005 • 272 citations

Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339

2005 • 248 citations

Riboflavin and rat hepatic cell structure and function. Mitochondrial oxidative metabolism in deficiency states.

1979 • 238 citations

The lipolysis/esterification cycle of hepatic triacylglycerol. Its role in the secretion of very-low-density lipoprotein and its response to hormones and sulphonylureas

1992 • 230 citations

Factors underlying the variability of lipid droplet fluorescence in MA‐10 leydig tumor cells

1994 • 221 citations

Lysosome membrane lipid microdomains: novel regulators of chaperone-mediated autophagy

2006 • 200 citations

Hepatocyte CYP2E1 Overexpression and Steatohepatitis Lead to Impaired Hepatic Insulin Signaling

2005 • 194 citations

Degradation of Proteasomes by Lysosomes in Rat Liver

1995 • 191 citations

PLD1 and ERK2 regulate cytosolic lipid droplet formation

2006 • 166 citations

Isolation of autophagic vacuoles from rat liver: morphological and biochemical characterization.

1982 • 150 citations

Degradation of Proteasomes by Lysosomes in Rat Liver

1995 • 134 citations

Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas

2005 • 133 citations

Loss of Macroautophagy Promotes or Prevents Fibroblast Apoptosis Depending on the Death Stimulus

2007 • 131 citations

Isolation of Lipid Droplets from Cells by Density Gradient Centrifugation

2005 • 128 citations

Energy Metabolism in Feasting and Fasting

1979 • 112 citations

Hepatocyte Resistance to Oxidative Stress Is Dependent on Protein Kinase C-mediated Down-regulation of c-Jun/AP-1

2004 • 77 citations

Isolation of Lipid Droplets from Cells by Density Gradient Centrifugation

2016 • 69 citations

Evidence that newly synthesized esterified cholesterol is deposited in existing cytoplasmic lipid inclusions

2001 • 31 citations

Roles of phosphatidylinositol 3-kinase and osteopontin in steatosis and aminotransferase release by hepatocytes treated with methionine-choline-deficient medium

2006 • 29 citations