The lipolysis/esterification cycle of hepatic triacylglycerol. Its role in the secretion of very-low-density lipoprotein and its response to hormones and sulphonylureas

Oleate stimulates secretion of apolipoprotein B-containing lipoproteins from Hep G2 cells by inhibiting early intracellular degradation of apolipoprotein B.

1991 • 421 citations

Hepatic Lipid Metabolism in Experimental Diabetes

1969 • 299 citations

Insulin modulation of hepatic synthesis and secretion of apolipoprotein B by rat hepatocytes.

1990 • 251 citations

Effects of Insulin and Glucose on Very Low Density Lipoprotein Triglyceride Secretion by Cultured Rat Hepatocytes

1982 • 215 citations

Apolipoprotein B is both integrated into and translocated across the endoplasmic reticulum membrane. Evidence for two functionally distinct pools.

1990 • 192 citations

Degradation of newly synthesized apolipoprotein B-100 in a pre-Golgi compartment.

1990 • 182 citations

Role of insulin in lipoprotein secretion by cultured rat hepatocytes.

1983 • 168 citations

The Regulation of Gluconeogenesis

1970 • 153 citations

Effects of NIDDM on Very-Low-Density Lipoprotein Triglyceride and Apolipoprotein B Metabolism: Studies Before and After Sulfonylurea Therapy

1986 • 149 citations

Effects of dexamethasone and insulin on the synthesis of triacylglycerols and phosphatidylcholine and the secretion of very-low-density lipoproteins and lysophosphatidylcholine by monolayer cultures of rat hepatocytes

1986 • 127 citations

The assembly and secretion of apoB 100 containing lipoproteins in Hep G2 cells. Evidence for different sites for protein synthesis and lipoprotein assembly.

1990 • 123 citations

Short- and longer-term regulation of very-low-density lipoprotein secretion by insulin, dexamethasone and lipogenic substrates in cultured hepatocytes. A biphasic effect of insulin

1988 • 123 citations

Insulin effects on apolipoprotein B lipoprotein synthesis and secretion by primary cultures of rat hepatocytes

1986 • 116 citations

Effects of hormones on the rate of the triacylglycerol/fatty acid substrate cycle in adipocytes and epididymal fat pads

1982 • 100 citations

Formation and turnover of triglyceride-rich vesicles in the chick liver cell. Effects of cAMP and carnitine on triglyceride mobilization and conversion to ketones.

1981 • 88 citations

Lysosomal triacylglycerol lipase and lipolysis in isolated rat hepatocytes.

1979 • 75 citations

The role of pancreatic hormones in the regulation of lipid storage, oxidation and secretion in primary cultures of rat hepatocytes. Short- and long-term effects

1992 • 72 citations

Effects of hormones and pyruvate on the rates of secretion of very-low-density lipoprotein triacylglycerol and cholesterol by rat hepatocytes

1985 • 60 citations

Contribution of cytoplasmic storage triacylglycerol to VLDL-triacylglycerol in isolated rat hepatocytes

1989 • 58 citations

Insulin regulates apolipoprotein B turnover and phosphorylation in rat hepatocytes.

1990 • 54 citations

Storage, mobilization and secretion of cytosolic triacylglycerol in hepatocyte cultures. The role of insulin

1990 • 53 citations

Contributin of floating fat triglyceride and of lecithin towards formation of secretory triglyceride in perfused rat live

1971 • 47 citations

Long-term maintenance of high rates of very-low-density-lipoprotein secretion in hepatocyte cultures. A model for studying the direct effects of insulin and insulin deficiency in vitro

1989 • 45 citations

Insulin effects on apolipoprotein B production by normal, diabetic and treated-diabetic rat liver and cultured rat hepatocytes

1989 • 37 citations

Lipid synthesis and ultrastructure of adult rat hepatocytes during their first twenty-four hours in culture

1978 • 37 citations

Lipolysis of hepatic triacylglycerol stores

1982 • 36 citations

Differentiation of microsomal from lysosomal triacylglycerol lipase activities in rat liver

1983 • 34 citations

Regulation of very-low-density-lipoprotein lipid secretion in hepatocyte cultures derived from diabetic animals

1989 • 33 citations

Effect of sulfonylureas on triglyceride metabolism in the rat liver: possible role of the lysosomes in hepatic lipolysis.

1977 • 31 citations

Control of Hepatic Triacylglycerol Metabolism

1976 • 26 citations

Control of Lipolysis in Isolated Hepatocytes by Insulin and Glucagon

1981 • 11 citations

Lowering of blood ketone bodies induced by drugs preventing free fatty acid mobilization

1966 • 9 citations

Transport and metabolism of extracellular free fatty acids in adipose tissue of fed and fasted mice

1987 • 7 citations

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