Back to search

CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

Data up to Jan 2025

Published2000
Citations746
References47

Total Citations Per Year

Abstract

References (47)

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

1979 • 27,693 citations

Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity☆, ☆☆

1999 • 3,339 citations

Fundamentals of Clinical Chemistry.

1977 • 2,670 citations

Nonalcoholic Steatohepatitis Mayo Clinic Experiences With a Hitherto Unnamed Disease

1980 • 2,667 citations

Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting

1999 • 1,589 citations

The natural history of nonalcoholic steatohepatitis: A follow-up study of forty-two patients for up to 21 years

1990 • 1,475 citations

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

1991 • 1,173 citations

A critical role for the peroxisome proliferator-activated receptor α (PPARα) in the cellular fasting response: The PPARα-null mouse as a model of fatty acid oxidation disorders

1999 • 931 citations

The natural history of nonalcoholic fatty liver: A follow-up study

1995 • 898 citations

Cytochrome P-4502E1: its physiological and pathological role

1997 • 881 citations

Obesity increases sensitivity to endotoxin liver injury: Implications for the pathogenesis of steatohepatitis

1997 • 815 citations

Cytotoxicity and genotoxicity of lipid-oxidation products

1993 • 802 citations

Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis

1998 • 611 citations

Oxidative and reductive metabolism by cytochrome P450 2E1

1992 • 557 citations

Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression.

1995 • 536 citations

Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P-450 (P-450IIE1)

1989 • 527 citations

Nonalcoholic Steatohepatitis

1997 • 488 citations

Alcohollike liver disease in nonalcoholics

1988 • 485 citations

Hepatic steatosis: Innocent bystander or guilty party?

1998 • 395 citations

Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation

1996 • 391 citations

Non-alcoholic steatohepatitis (NASH): a disease of emerging identity and importance

1998 • 373 citations

Biochemical Mechanisms Of Induction Of Hepatic Peroxisome Proliferation

1989 • 356 citations

On the stoichiometry of the oxidase and monooxygenase reactions catalyzed by liver microsomal cytochrome P-450. Products of oxygen reduction.

1984 • 324 citations

Phosphatidylcholine protects against fibrosis and cirrhosis in the baboon

1994 • 306 citations

Diagnosis and interpretation of steatosis and steatohepatitis.

1998 • 289 citations

Acute and chronic hepatic steatosis lead to in vivo lipid peroxidation in mice

1996 • 277 citations

Markedly Enhanced Cytochrome P450 2E1 Induction and Lipid Peroxidation Is Associated with Severe Liver Injury in Fish Oil—Ethanol‐Fed Rats

1994 • 265 citations

Mechanisms of hydroxyl radical formation and ethanol oxidation by ethanol-inducible and other forms of rabbit liver microsomal cytochromes P-450.

1984 • 246 citations

Stable expression of human cytochrome P4502E1 in HepG2 cells: Characterization of catalytic activities and production of reactive oxygen intermediates

1993 • 244 citations

Peroxisome Proliferator-activated Receptor α Controls the Hepatic CYP4A Induction Adaptive Response to Starvation and Diabetes

1998 • 211 citations

Ribonuclease Protection Assay

1993 • 207 citations

Cytotoxicity and Apoptosis Produced by Arachidonic Acid in Hep G2 Cells Overexpressing Human Cytochrome P4502E1

1997 • 198 citations

Microvesicular steatosis and steatohepatitis: role of mitochondrial dysfunction and lipid peroxidation

1997 • 169 citations

CYP2E1 is not involved in early alcohol-induced liver injury

1999 • 160 citations

Polyenylphosphatidylcholine Decreases Alcohol-Induced Oxidative Stress in the Baboon

1997 • 140 citations

Lipid Peroxidation, CYP2E1 and Arachidonic Acid Metabolism in Alcoholic Liver Disease in Rats

1997 • 99 citations

The biochemistry of alcohol-induced fatty liver

1994 • 90 citations

Induction of cytochrome P450III and P450IV family proteins in streptozotocin-induced diabetes

1990 • 87 citations

Species-specific induction of cytochrome P-450 4A RNAs: PCR cloning of partial guinea-pig, human and mouse CYP4A cDNAs

1993 • 86 citations

A novel murine P-450 gene, Cyp4a14, is part of a cluster of Cyp4a and Cyp4b, but not of CYP4F, genes in mouse and humans

1997 • 81 citations

On the Stoichiometry of the Oxidase and Monooxygenase Reactions Catalyzed by Liver Microsomal Cytochrome P-450

1984 • 79 citations

Drug metabolism in cirrhosis

1986 • 77 citations

Possible role of aldehydic lipid peroxidation products as chemoattractants.

1987 • 53 citations

cDNA sequence, deduced amino acid sequence, predicted gene structure and chemical regulation of mouse Cyp2e1

1992 • 37 citations

Estimation of chlorzoxazone hydroxylase activity in liver microsomes and of the plasma pharmacokinetics of chlorzoxazone by the same high-performance liquid chromatographic method

1998 • 32 citations

Cited By (0)

No citing papers found in database

CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic… (2000) – Journal of Clinical Investigation | Metascience Observatory Explorer