Relation of the [3H]γ-hydroxybutyric acid (ghb) binding site to the γ-aminobutyric acidb (gabab) receptor in rat brain

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1982 • 53,055 citations

The rat brain in stereotaxic coordinates

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A G Protein Couples Serotonin and GABA _B Receptors to the Same Channels in Hippocampus

1986 • 870 citations

GABAA and GABAB receptor site distribution in the rat central nervous system

1987 • 865 citations

A practical computer-based approach to the analysis of radioligand binding experiments

1983 • 834 citations

The Role of GABA _B Receptor Activation in Absence Seizures of Lethargic ( lh / lh ) Mice

1992 • 355 citations

Distribution and kinetics of GABAB binding sites in rat central nervous system: A quantitative autoradiographic study

1990 • 347 citations

[41] LIGAND: A computerized analysis of ligand binding data

1983 • 324 citations

Involvement of intrathalamic GABAb neurotransmission in the control of absence seizures in the rat

1992 • 255 citations

The Pharmacology and Function of Central GabaB Receptors

1994 • 242 citations

Multiple GABAB receptors

1993 • 217 citations

High affinity binding site for γ-hydroxybutyric acid in rat brain

1982 • 207 citations

Evidence for GABAB-mediated mechanisms in experimental generalized absence seizures

1992 • 168 citations

Reverse intrinsic activity of antagonists on G protein-coupled receptors

1992 • 157 citations

Inhibition of GABA_B Receptor Binding by Guanyl Nucleotides

1984 • 150 citations

Gammahydroxybutyrate: An overview of the pros and cons for it being a neurotransmitter and/or a useful therapeutic agent

1994 • 149 citations

γ‐Hydroxybutyrate Model of Generalized Absence Seizures: Further Characterization and Comparison with Other Absence Models

1988 • 146 citations

A specific gamma-hydroxybutyrate receptor ligand possesses both antagonistic and anticonvulsant properties.

1990 • 146 citations

Biochemical pharmacology of Gabaergic agonists

1979 • 128 citations

Gamma hydroxybutyrate in the monkey

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1991 • 124 citations

The γ-hydroxybutyrate model of absence seizures: correlation of regional brain levels of γ-hydroxybutyric acid and γ-butyrolactone with spike wave discharges

1991 • 112 citations

GABAB receptor modulation of Ca2+ currents in rat sensory neurones by the G protein G(0): antisense oligonucleotide studies.

1993 • 110 citations

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1993 • 107 citations

Presynaptic gamma-hydroxybutyric acid (GHB) and gamma-aminobutyric acidB (GABAB) receptor-mediated release of GABA and glutamate (GLU) in rat thalamic ventrobasal nucleus (VB): a possible mechanism for the generation of absence-like seizures induced by GHB.

1995 • 103 citations

γ-Hydroxybutyrate hyperpolarizes hippocampal neurones by activating GABAB receptors

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In vivo conversion of γ-aminobutyric acid and 1,4-butanediol to γ-hydroxybutyric acid in rat brain

1989 • 89 citations

PURIFICATION FROM HUMAN BRAIN AND SOME PROPERTIES OF TWO NADPH‐LINKED ALDEHYDE REDUCTASES WHICH REDUCE SUCCINIC SEMIALDEHYDE TO 4‐HYDROXYBUTYRATE

1979 • 88 citations

Gamma-hydroxybutyrate promotes oscillatory activity of rat and cat thalamocortical neurons by a tonic GABAB receptor-mediated hyperpolarization

1995 • 85 citations

The ontogeny of [ 3 H]γ-hydroxybutyrate and [ 3 H]GABA B binding sites: relation to the development of experimental absence seizures

1994 • 84 citations

Experimental absence seizures: potential role of γ-hydroxybutyric acid and GABAB receptors

1992 • 82 citations

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Functional evidence for multiple gamma-aminobutyric acidB receptor subtypes in the rat cerebral cortex.

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Antiabsence seizure activity of specific GABAB and γ-hydroxybutyric acid receptor antagonists

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Gamma hydroxybutyrate distribution and turnover rates in discrete brain regions of the rat

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Pertussis toxin in the analysis of receptor mechanisms

1990 • 64 citations

Regional and Subcellular Localization in Rat Brain of the Enzymes That Can Synthesize γ‐Hydroxybutyric Acid

1981 • 59 citations

Regional Distribution of High‐Affinity γ‐[³H] Hydroxybutyrate Binding Sites as Determined by Quantitative Autoradiography

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Depolarization‐Evoked Release of γ‐Hydroxybutyrate from Rat Brain Slices

1983 • 55 citations

γ-Hydroxybutyric acid induced spike and wave discharges in rats: Relation to high-affinity [3H]γ-hydroxybutyric acid binding sites in the thalamus and cortex

1993 • 54 citations

Characterization of the antiabsence effects of SCH 50911, a GABA-B receptor antagonist, in the lethargic mouse, gamma-hydroxybutyrate, and pentylenetetrazole models.

1995 • 53 citations

Thalamic mediodorsal and intralaminar nuclear lesions disrupt the generation of experimentally induced generalized absence-like seizures in rats

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GABA_B receptors couple to G proteins G_o, G^∗_o and G·_i1 but not to G_i2

1990 • 47 citations

?-Hydroxybutyrate uptake by rat brain striatal slices

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GABAA receptor function in the γ-hydroxybutyrate model of generalized absence seizures

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γ-Hydroxybutyric acid binding sites: Evidence for coupling to a chloride anion channel

1987 • 40 citations

γ‐Hydroxybutyric Acid in Subcellular Fractions of Rat Brain

1987 • 34 citations

Presynaptic inhibitory effect of baclofen on hippocampal inhibitory synaptic transmission involves a pertussis toxin-sensitive G-protein

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Increased γ-hydroxybutyric acid receptors in thalamus of a genetic animal model of petit mal epilepsy

1990 • 26 citations

Immunocytochemical localization in rat brain of the enzyme that synthesizes γ-hydroxybutyric acid

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Intrathalamic injections of γ-hydroxybutyric acid increase genetic absence seizures in rats

1991 • 21 citations

The actions of 3-aminopropanephosphinic acid at GABAB receptors in rat hippocampus

1992 • 14 citations