Back to search

GABAB receptor antagonists: from synthesis to therapeutic applications

Data up to Jan 2025

Published1993
Citations107
References16

Total Citations Per Year

Abstract

References (16)

A physiological role for GABAB receptors in the central nervous system

1988 • 643 citations

The Role of GABA B Receptor Activation in Absence Seizures of Lethargic ( lh / lh ) Mice

1992 • 355 citations

Phaclofen: a peripheral and central baclofen antagonist

1987 • 349 citations

CGP 35348: a centrally active blocker of GABAB receptors

1990 • 303 citations

2-Hydroxy-saclofen: an improved antagonist at central and peripheral GABAB receptors

1988 • 202 citations

Upregulation of gamma-aminobutyric acid (GABA) B binding sites in rat frontal cortex: a common action of repeated administration of different classes of antidepressants and electroshock.

1985 • 197 citations

GABAB receptors in mammalian function

1991 • 146 citations

CGP 36742: The first orally active GABAB blocker improves the cognitive performance of mice, rats, and rhesus monkeys

1993 • 119 citations

The actions of orally active GABAB receptor antagonists on GABAergic transmission in vivo and in vitro

1993 • 92 citations

CGP 35348, a new GABAB antagonist, prevents antinociception and muscle‐relaxant effect induced by baclofen

1991 • 73 citations

Functional evidence for multiple gamma-aminobutyric acidB receptor subtypes in the rat cerebral cortex.

1992 • 72 citations

Repeated administration of desipramine and a GABAB receptor antagonist, CGP 36742, discretely up‐regulates GABAB receptor binding sites in rat frontal cortex

1993 • 64 citations

Are increases in GABAB receptors consistent findings following chronic antidepressant administration?

1987 • 53 citations

Phaclofen: a GABAB blocker reduces long-duration inhibition in the neocortex

1988 • 42 citations

Inhibition of baolofen-induced hypothermia in mice by the novel GABAB antagonist CGP 35348

1991 • 25 citations

Increased acetylcholine and quisqualate responsiveness after blockade of GABAB receptors

1992 • 23 citations

Cited By (0)

Loading...
GABAB receptor antagonists: from synthesis to therapeutic applications (1993) – Trends in Pharmacological Sciences | Metascience Observatory Explorer