High affinity binding site for γ-hydroxybutyric acid in rat brain

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

REGIONAL STUDIES OF CATECHOLAMINES IN THE RAT BRAIN‐I

1966 • 5,429 citations

Multiple serotonin receptors: differential binding of [3H]5-hydroxytryptamine, [3H]lysergic acid diethylamide and [3H]spiroperidol.

1979 • 1,321 citations

3H-baclofen and 3H-GABA bind to bicuculline-insensitive GABAB sites in rat brain

1981 • 1,044 citations

GABA‐Benzodiazepine‐Barbiturate Receptor Interactions

1981 • 910 citations

Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures.

1972 • 760 citations

Mathematical theory of complex ligand-binding systems at equilibrium: Some methods for parameter fitting

1972 • 615 citations

Morphological and biochemical maturation of neurones cultured in the absence of glial cells

1979 • 325 citations

Dopaminergic neurons: drug-induced antagonism of the increase in tyrosine hydroxylase activity produced by cessation of impulse flow.

1974 • 208 citations

Selective increase of brain dopamine induced by gamma-hydroxybutyrate

1966 • 198 citations

Natural occurrence of gamma-hydroxybutyrate in mammalian brain

1970 • 169 citations

Effect of gamma-hydroxybutyrate on dopamine and dopamine metabolites in the rat striatum

1972 • 164 citations

gamma-Aminobutyric acid receptor binding in mammalian brain. Heterogeneity of binding sites.

1981 • 150 citations

Identification of endogenous gamma-hydroxybutyrate in human and bovine brain and its regional distribution in human, guinea pig and rhesus monkey brain.

1978 • 144 citations

Gamma hydroxybutyrate in the monkey

1978 • 126 citations

Gamma hydroxybutyrate

1977 • 115 citations

Slow wave sleep and a state resembling absence epilepsy induced in the rat by γ-hydroxybutyrate

1977 • 114 citations

Differential Estimation of Gamma-butyrolactone and Gamma-hydroxybutyric Acid in Rat Blood and Brain

1964 • 95 citations

Human Brain Aldehyde Reductases: Relationship to Succinic Semialdehyde Reductase and Aldose Reductase

1980 • 93 citations

EFFECTS OF γ‐BUTYROLACTONE ON LOCAL CEREBRAL GLUCOSE UTILIZATION IN THE RAT

1977 • 91 citations

PURIFICATION FROM HUMAN BRAIN AND SOME PROPERTIES OF TWO NADPH‐LINKED ALDEHYDE REDUCTASES WHICH REDUCE SUCCINIC SEMIALDEHYDE TO 4‐HYDROXYBUTYRATE

1979 • 88 citations

Ontogeny of γ-hydroxybutyric acid. I. Regional concentration in developing rat, monkey and human brain

1981 • 77 citations

Gamma-hydroxybutyrate-induced increase in brain dopamine: localization by fluorescence microscopy.

1970 • 70 citations

EEG and behavioral comparison of the effects of gamma-hydroxybutyrate, gamma-butyro-lactone and short chain fatty acids in the rat

1967 • 69 citations

Antagonism of gamma-hydroxybutyrate-induced hypersynchronization in the ECoG of the rat by anti-petit mal drugs

1976 • 66 citations

Effect of acute and chronic anticonvulsant administration on endogenous γ-hydroxybutyrate in rat brain

1980 • 66 citations

Baclofen and γ-hydroxybutyrate: similar effects on cerebral dopamine neurones

1976 • 65 citations

Regional and Subcellular Localization in Rat Brain of the Enzymes That Can Synthesize γ‐Hydroxybutyric Acid

1981 • 59 citations

Specific and non‐specific succinic semialdehyde reductases from rat brain: Isolation and properties

1980 • 57 citations

Inhibition of nigral and neocortical cells by γ-hydroxybutyrate: A microiontophoretic investigation

1979 • 44 citations

Evidence that a specific succinic semialdehyde reductase is responsible for λ‐hydroxybutyrate synthesis in brain tissue slices

1981 • 43 citations

THE ACTION OF GAMMA‐HYDROXYBUTYRIC ACID ON CEREBRAL GLUCOSE METABOLISM

1972 • 37 citations

Inhibition by dopamine agonists of dopamine accumulation following γ-hydroxybutyrate treatment

1975 • 36 citations

REGIONAL BRAIN LEVELS OF γ‐HYDROXYBUTYRATE IN HUNTINGTON'S DISEASE

1979 • 31 citations

Gamma hydroxybutyrate in the monkey

1978 • 30 citations

Catecholamine Concentration in the Developing Rat Brain after γ‐Hydroxybutyric Acid

1980 • 24 citations

Inverse relationship between GABA and γ‐hydoxybutyrate levels in striatum of rat injected with kainic acid

1979 • 15 citations

A comparison of the effects of γ-hydroxybutyrate and γ-butyrolactone on cerebral carbohydrate metabolism

1979 • 11 citations