Ontogeny of postsynaptic density proteins at glutamatergic synapses

What's wrong with Bonferroni adjustments

1998 • 5,540 citations

No Adjustments Are Needed for Multiple Comparisons

1990 • 5,157 citations

AMPA Receptor Trafficking at Excitatory Synapses

2003 • 1,121 citations

Coupling of mGluR/Homer and PSD-95 Complexes by the Shank Family of Postsynaptic Density Proteins

1999 • 1,024 citations

Light and electron immunocytochemical localization of AMPA‐selective glutamate receptors in the rat brain

1992 • 988 citations

Shank, a Novel Family of Postsynaptic Density Proteins that Binds to the NMDA Receptor/PSD-95/GKAP Complex and Cortactin

1999 • 980 citations

Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody

1994 • 860 citations

Long-term potentiation and functional synapse induction in developing hippocampus

1996 • 787 citations

Synaptogenesis Via Dendritic Filopodia in Developing Hippocampal Area CA1

1998 • 756 citations

Postsynaptic Signaling and Plasticity Mechanisms

2002 • 713 citations

Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses

1999 • 669 citations

Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: An in situ hybridization study in adult and developing rat

1992 • 645 citations

Homer Regulates the Association of Group 1 Metabotropic Glutamate Receptors with Multivalent Complexes of Homer-Related, Synaptic Proteins

1998 • 630 citations

Regional distribution of type II Ca2+/calmodulin-dependent protein kinase in rat brain

1985 • 625 citations

SynGAP: a Synaptic RasGAP that Associates with the PSD-95/SAP90 Protein Family

1998 • 617 citations

Assembly of presynaptic active zones from cytoplasmic transport packets

2000 • 602 citations

Brain-Derived Neurotrophic Factor/TrkB Signaling in Memory Processes

2003 • 550 citations

A Developmental Change in NMDA Receptor-Associated Proteins at Hippocampal Synapses

2000 • 521 citations

GKAP, a Novel Synaptic Protein That Interacts with the Guanylate Kinase-like Domain of the PSD-95/SAP90 Family of Channel Clustering Molecules

1997 • 503 citations

The catenin/cadherin adhesion system is localized in synaptic junctions bordering transmitter release zones.

1996 • 500 citations

Selective acquisition of AMPA receptors over postnatal development suggests a molecular basis for silent synapses

1999 • 496 citations

The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1

1994 • 481 citations

Review: Fine structure of synaptogenesis in the vertebrate central nervous system

1989 • 426 citations

Assembling the Presynaptic Active Zone

2001 • 421 citations

Organization of AMPA Receptor Subunits at a Glutamate Synapse: A Quantitative Immunogold Analysis of Hair Cell Synapses in the Rat Organ of Corti

1996 • 416 citations

Homer: a link between neural activity and glutamate receptor function

2000 • 405 citations

Heterogeneity in the Molecular Composition of Excitatory Postsynaptic Sites during Development of Hippocampal Neurons in Culture

1998 • 396 citations

Regulation of Dendritic Spine Morphology by SPAR, a PSD-95-Associated RapGAP

2001 • 383 citations

Ankyrin-Based Subcellular Gradient of Neurofascin, an Immunoglobulin Family Protein, Directs GABAergic Innervation at Purkinje Axon Initial Segment

2004 • 369 citations

Trafficking of NMDA Receptors

2003 • 364 citations

Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1

2003 • 354 citations

NMDA receptor trafficking through an interaction between PDZ proteins and the exocyst complex

2003 • 323 citations

Selective Regulation of Neurite Extension and Synapse Formation by the β but not the α Isoform of CaMKII

2003 • 320 citations

N-Cadherin Redistribution during Synaptogenesis in Hippocampal Neurons

1998 • 311 citations

Switching of NMDA Receptor 2A and 2B Subunits at Thalamic and Cortical Synapses during Early Postnatal Development

2004 • 309 citations

Targeted Protein Degradation and Synapse Remodeling by an Inducible Protein Kinase

2003 • 302 citations

Mechanisms of Synapse Assembly and Disassembly

2003 • 297 citations

Cellular and molecular mechanisms of presynaptic assembly

2004 • 295 citations

Cellular signaling by neural cell adhesion molecules of the immunoglobulin superfamily

2000 • 290 citations

Laminar Organization of the NMDA Receptor Complex within the Postsynaptic Density

2001 • 290 citations

Selective scarcity of NMDA receptor channel subunits in the stratum lucidum (mossy fibre‐recipient layer) of the mouse hippocampal CA3 subfield

1998 • 289 citations

The Establishment of GABAergic and Glutamatergic Synapses on CA1 Pyramidal Neurons is Sequential and Correlates with the Development of the Apical Dendrite

1999 • 287 citations

Developmental and mature expression of full-length and truncated TrkB, receptors in the rat forebrain

1996 • 281 citations

vesl, a gene encoding VASP/Ena family related protein, is upregulated during seizure, long‐term potentiation and synaptogenesis¹

1997 • 278 citations

Characterization of the Shank Family of Synaptic Proteins

1999 • 273 citations

Synapse-Associated Protein 97 Selectively Associates with a Subset of AMPA Receptors Early in their Biosynthetic Pathway

2001 • 259 citations

Impairment of AMPA Receptor Function in Cerebellar Granule Cells of Ataxic Mutant MouseStargazer

1999 • 253 citations

Receptor compartmentalization and trafficking at glutamate synapses: a developmental proposal

2004 • 247 citations

A Developmental Switch in Neurotransmitter Flux Enhances Synaptic Efficacy by Affecting AMPA Receptor Activation

2001 • 226 citations

Disruption of TrkB-Mediated Signaling Induces Disassembly of Postsynaptic Receptor Clusters at Neuromuscular Junctions

1999 • 221 citations

Ultrastructural Localization of Full-Length trkB Immunoreactivity in Rat Hippocampus Suggests Multiple Roles in Modulating Activity-Dependent Synaptic Plasticity

1999 • 219 citations

Regulation of neurotrophin receptor expression during embryonic and postnatal development

1994 • 208 citations

Structural and Functional Evolution of the L1 Family: Are Four Adhesion Molecules Better Than One?

2000 • 205 citations

Molecular mechanisms of CNS synaptogenesis

2002 • 204 citations

Conditional Ablation of the Neural Cell Adhesion Molecule Reduces Precision of Spatial Learning, Long-Term Potentiation, and Depression in the CA1 Subfield of Mouse Hippocampus

2004 • 186 citations

Some assembly required: the development of neuronal synapses

2003 • 181 citations

Glutamate-induced transient modification of the postsynaptic density

2001 • 174 citations

Postsynaptic Density Assembly Is Fundamentally Different from Presynaptic Active Zone Assembly

2004 • 169 citations

Developmental expression of the CaM kinase II isoforms: ubiquitous γ- and δ-CaM kinase II are the early isoforms and most abundant in the developing nervous system

1999 • 167 citations

Neural cell adhesion molecule promotes accumulation of TGN organelles at sites of neuron-to-neuron contacts

2002 • 164 citations

Differential Distribution of Group I Metabotropic Glutamate Receptors during Rat Cortical Development

2002 • 163 citations

Distribution of Kainate Receptor Subunits at Hippocampal Mossy Fiber Synapses

2003 • 145 citations

NMDA-Dependent Proteolysis of Presynaptic Adhesion Molecule L1 in the Hippocampus by Neuropsin

2003 • 139 citations

Induction of noncatalytic TrkB neurotrophin receptors during axonal sprouting in the adult hippocampus

1993 • 135 citations

Covalent and Noncovalent Interactions Mediate Metabotropic Glutamate Receptor mGlu₅Dimerization

2001 • 129 citations

Postsynaptic TrkB-Mediated Signaling Modulates Excitatory and Inhibitory Neurotransmitter Receptor Clustering at Hippocampal Synapses

2004 • 123 citations

Characterization of Guanylate Kinase-Associated Protein, a Postsynaptic Density Protein at Excitatory Synapses That Interacts Directly with Postsynaptic Density-95/Synapse-Associated Protein 90

1997 • 122 citations

Glutamate Receptor Targeting to Synaptic Populations on Purkinje Cells Is Developmentally Regulated

1998 • 120 citations

Decline of the Critical Period of Visual Plasticity Is Concurrent with the Reduction of NR2B Subunit of the Synaptic NMDA Receptor in Layer 4

2003 • 116 citations

Endbulb synapses in the anteroventral cochlear nucleus express a specific subset of AMPA-type glutamate receptor subunits.

1998 • 115 citations

Close Homolog of L1 Modulates Area-Specific Neuronal Positioning and Dendrite Orientation in the Cerebral Cortex

2004 • 114 citations

Direct interaction of GluRδ2 with Shank scaffold proteins in cerebellar Purkinje cells

2004 • 112 citations

Functional trkB neurotrophin receptors are intrinsic components of the adult brain postsynaptic density

1996 • 112 citations

Endbulb Synapses in the Anteroventral Cochlear Nucleus Express a Specific Subset of AMPA-Type Glutamate Receptor Subunits

1998 • 112 citations

The mGlu5 metabotropic glutamate receptor is expressed in zones of active neurogenesis of the embryonic and postnatal brain

2004 • 111 citations

Eye opening induces a rapid dendritic localization of PSD-95 in central visual neurons

2003 • 110 citations

Localization of brain-derived neurotrophic factor and trkb receptors to postsynaptic densities of adult rat cerebral cortex

2000 • 107 citations

Distinct Roles of Different Neural Cell Adhesion Molecule (NCAM) Isoforms in Synaptic Maturation Revealed by Analysis of NCAM 180 kDa Isoform-Deficient Mice

2004 • 106 citations

Internalization at glutamatergic synapses during development

2003 • 106 citations

Decreased Anxiety, Altered Place Learning, and Increased CA1 Basal Excitatory Synaptic Transmission in Mice with Conditional Ablation of the Neural Cell Adhesion Molecule L1

2003 • 103 citations

Differential expression of Homer family proteins in the developing mouse brain

2004 • 102 citations

Bravo/Nr-CAM is closely related to the cell adhesion molecules L1 and Ng-CAM and has a similar heterodimer structure.

1992 • 102 citations

Binding between the neural cell adhesion molecules axonin-1 and Nr-CAM/Bravo is involved in neuron-glia interaction.

1995 • 95 citations

Changes in the subcellular distribution of calmodulin-kinase II during brain development

1985 • 94 citations

Synaptic targeting of neuroligin is independent of neurexin and SAP90/PSD95 binding

2004 • 90 citations

Trans-Golgi network delivery of synaptic proteins in synaptogenesis

2003 • 83 citations

Identification of the border between fibronectin type III homologous repeats 2 and 3 of the neural cell adhesion molecule L1 as a neurite outgrowth promoting and signal transducing domain

1995 • 79 citations

Nr‐CAM expression in the developing mouse nervous system: Ventral midline structures, specific fiber tracts, and neuropilar regions

2001 • 79 citations

NMDA receptor subunits GluRε1, GluRε3 and GluRζ1 are enriched at the mossy fibre–granule cell synapse in the adult mouse cerebellum

2001 • 78 citations

Immunocytochemistry of NMDA Receptors

2003 • 75 citations

Homer/Vesl Proteins and Their Roles in CNS Neurons

2004 • 75 citations

Variations in the tangential distribution of postsynaptic glutamate receptors in Purkinje cell parallel and climbing fiber synapses during development

1998 • 62 citations

Glutamate receptor targeting in the postsynaptic spine involves mechanisms that are independent of myosin Va

2001 • 62 citations

L1/Laminin Modulation of Growth Cone Response to EphB Triggers Growth Pauses and Regulates the Microtubule Destabilizing Protein SCG10

2004 • 60 citations

NCAM180 and glutamate receptor subtypes in potentiated spine synapses: an immunogold electron microscopic study

2003 • 52 citations

NrCAM, cerebellar granule cell receptor for the neuronal adhesion molecule F3, displays an actin-dependent mobility in growth cones

1999 • 47 citations

NMDA receptors and PSD‐95 are found in attachment plaques in cerebellar granular layer glomeruli

2002 • 40 citations

A role for BDNF in early postnatal rat vestibular epithelia maturation: implication of supporting cells

1998 • 36 citations

Distribution of brain‐derived neurotrophic factor and TrkB receptor proteins in the fetal and postnatal hippocampus and cerebellum of the guinea pig

2002 • 34 citations

Developmental regulation of metabotropic glutamate receptor 5b protein in rodent brain

2002 • 32 citations

The cell outgrowth secretory endosome (COSE): a specialized compartment involved in neuronal morphogenesis

2003 • 30 citations

Early onset of NMDA receptor GluRε1 (NR2A) expression and its abundant postsynaptic localization in developing motoneurons of the mouse hypoglossal nucleus

2002 • 26 citations

Chapter 1 Biochemistry and anatomy of transmitter glutamate

2000 • 25 citations

Loss of GLUR2 α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazoleproprionic acid receptor subunit differentially affects remaining synaptic glutamate receptors in cerebellum and cochlear nuclei

2004 • 18 citations

TRKB signalling controls the expression of N‐methyl‐<scp>d</scp>‐aspartate receptors in the visual cortex

2002 • 5 citations