Homer: a link between neural activity and glutamate receptor function

Neuronal Calcium Signaling

1998 • 2,126 citations

Dendritic spines of CA 1 pyramidal cells in the rat hippocampus: serial electron microscopy with reference to their biophysical characteristics

1989 • 1,069 citations

Homer: a protein that selectively binds metabotropic glutamate receptors

1997 • 1,058 citations

Isolation of a novel gene mutated in Wiskott-Aldrich syndrome

1994 • 1,053 citations

Coupling of mGluR/Homer and PSD-95 Complexes by the Shank Family of Postsynaptic Density Proteins

1999 • 1,024 citations

Shank, a Novel Family of Postsynaptic Density Proteins that Binds to the NMDA Receptor/PSD-95/GKAP Complex and Cortactin

1999 • 980 citations

The metabotropic glutamate receptor (mGluRlα) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction

1993 • 905 citations

Wiskott–Aldrich Syndrome Protein, a Novel Effector for the GTPase CDC42Hs, Is Implicated in Actin Polymerization

1996 • 873 citations

Homer Binds a Novel Proline-Rich Motif and Links Group 1 Metabotropic Glutamate Receptors with IP3 Receptors

1998 • 852 citations

Metabotropic glutamate receptors: Synaptic transmission, modulation, and plasticity

1994 • 713 citations

N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases.

1996 • 667 citations

Mena, a Relative of VASP and Drosophila Enabled, Is Implicated in the Control of Microfilament Dynamics

1996 • 667 citations

Homer Regulates the Association of Group 1 Metabotropic Glutamate Receptors with Multivalent Complexes of Homer-Related, Synaptic Proteins

1998 • 630 citations

Three-Dimensional Organization of Smooth Endoplasmic Reticulum in Hippocampal CA1 Dendrites and Dendritic Spines of the Immature and Mature Rat

1997 • 599 citations

Single Synaptic Events Evoke NMDA Receptor–Mediated Release of Calcium from Internal Stores in Hippocampal Dendritic Spines

1999 • 437 citations

Subsynaptic segregation of metabotropic and ionotropic glutamate receptors as revealed by immunogold localization

1994 • 420 citations

A novel proline-rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family

1997 • 414 citations

Differential plasma membrane distribution of metabotropic glutamate receptors mGluR1α, mGluR2 and mGluR5, relative to neurotransmitter release sites

1997 • 391 citations

Protein kinase C modulation of NMDA currents: an important link for LTP induction

1992 • 350 citations

A Complex Program of Striatal Gene Expression Induced by Dopaminergic Stimulation

1998 • 333 citations

The inositol 1,4,5,-trisphosphate receptor in cerebellar Purkinje cells: quantitative immunogold labeling reveals concentration in an ER subcompartment.

1990 • 326 citations

Dendritic spines of rat cerebellar Purkinje cells: serial electron microscopy with reference to their biophysical characteristics

1988 • 316 citations

vesl, a gene encoding VASP/Ena family related protein, is upregulated during seizure, long‐term potentiation and synaptogenesis¹

1997 • 278 citations

Complex interactions between mGluRs, intracellular Ca2+ stores and ion channels in neurons

2000 • 278 citations

Novel Members of the Vesl/Homer Family of PDZ Proteins That Bind Metabotropic Glutamate Receptors

1998 • 277 citations

Structure of the Enabled/VASP Homology 1 Domain–Peptide Complex

1999 • 241 citations

Homer 1b Regulates the Trafficking of Group I Metabotropic Glutamate Receptors

1999 • 211 citations

Proline-Rich Synapse-Associated Proteins ProSAP1 and ProSAP2 Interact with Synaptic Proteins of the SAPAP/GKAP Family

1999 • 192 citations

Structure of the Homer EVH1 Domain-Peptide Complex Reveals a New Twist in Polyproline Recognition

2000 • 166 citations

Selective activation of quisqualate metabotropic receptor potentiates NMDA but not AMPA responses

1991 • 135 citations

Involvement of unique leucine-zipper motif of PSD-Zip45 (Homer 1c/vesl-1L) in group 1 metabotropic glutamate receptor clustering

1999 • 127 citations

Structure of EVH1, a novel proline-rich ligand-binding module involved in cytoskeletal dynamics and neural function.

1999 • 118 citations

Homer-1c/Vesl-1L Modulates the Cell Surface Targeting of Metabotropic Glutamate Receptor Type 1α: Evidence for an Anchoring Function

2000 • 114 citations

A monoclonal antibody shows discrete cellular and subcellular localizations of mGluR1α metabotropic glutamate receptors

1997 • 107 citations

Cupidin, an Isoform of Homer/Vesl, Interacts with the Actin Cytoskeleton and Activated Rho Family Small GTPases and Is Expressed in Developing Mouse Cerebellar Granule Cells

1999 • 103 citations

Synamon, a Novel Neuronal Protein Interacting with Synapse-associated Protein 90/Postsynaptic Density-95-associated Protein

1999 • 96 citations

Synaptic [Ca2+]

1999 • 94 citations

Identification of homer as a homologue of the Wiskott-Aldrich Syndrome protein suggests a receptor-binding function for WH1 domains

1997 • 89 citations

Requirement of rapid Ca²⁺ entry and synaptic activation of metabotropic glutamate receptors for the induction of long‐term depression in adult rat hippocampus

1998 • 89 citations

Mouse brain and muscle tissues constitutively express high levels of Homer proteins

2000 • 79 citations

Isolation of PSD‐Zip45, a novel Homer/vesl family protein containing leucine zipper motifs, from rat brain¹

1998 • 74 citations

ABM-1 and ABM-2 Homology Sequences: Consensus Docking Sites for Actin-Based Motility Defined by Oligoproline Regions in Listeria ActA Surface Protein and Human VASP

1997 • 57 citations