Some assembly required: the development of neuronal synapses

Synaptic Activity and the Construction of Cortical Circuits

1996 • 3,004 citations

Excitatory actions of gaba during development: the nature of the nurture

2002 • 2,322 citations

The K+/Cl− co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation

1999 • 2,069 citations

CNS Synaptogenesis Promoted by Glia-Derived Cholesterol

2001 • 1,622 citations

Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neurons

2001 • 1,523 citations

Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion

2000 • 1,397 citations

Activation of postsynaptically silent synapses during pairing-induced LTP in CA1 region of hippocampal slice

1995 • 1,342 citations

Control of Synapse Number by Glia

2001 • 1,327 citations

Control of Synaptic Strength by Glial TNFα

2002 • 1,277 citations

PDZ Domains and the Organization of Supramolecular Complexes

2001 • 1,203 citations

Neuroligin Expressed in Nonneuronal Cells Triggers Presynaptic Development in Contacting Axons

2000 • 1,176 citations

Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein

1998 • 1,147 citations

Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms

2000 • 1,086 citations

Three-dimensional structure of dendritic spines and synapses in rat hippocampus (CA1) at postnatal day 15 and adult ages: implications for the maturation of synaptic physiology and long-term potentiation.

1992 • 1,080 citations

Dendritic spines of CA 1 pyramidal cells in the rat hippocampus: serial electron microscopy with reference to their biophysical characteristics

1989 • 1,069 citations

Induction, assembly, maturation and maintenance of a postsynaptic apparatus

2001 • 1,003 citations

Quantitative Ultrastructural Analysis of Hippocampal Excitatory Synapses

1997 • 973 citations

Dendritic Spines: Cellular Specializations Imparting Both Stability and Flexibility to Synaptic Function

1994 • 970 citations

Three-dimensional structure of dendritic spines and synapses in rat hippocampus (CA1) at postnatal day 15 and adult ages: implications for the maturation of synaptic physiology and long-term potentiation [published erratum appears in J Neurosci 1992 Aug;12(8):following table of contents]

1992 • 940 citations

Dentritic spines : structure, dynamics and regulation

2001 • 915 citations

Evidence for a Role of Dendritic Filopodia in Synaptogenesis and Spine Formation

1996 • 844 citations

Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins.

1998 • 834 citations

Cell Type and Pathway Dependence of Synaptic AMPA Receptor Number and Variability in the Hippocampus

1998 • 798 citations

Long-term potentiation and functional synapse induction in developing hippocampus

1996 • 787 citations

SynCAM, a Synaptic Adhesion Molecule That Drives Synapse Assembly

2002 • 780 citations

Synaptic Efficacy Enhanced by Glial Cells in Vitro

1997 • 771 citations

Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles

1999 • 759 citations

Synaptogenesis Via Dendritic Filopodia in Developing Hippocampal Area CA1

1998 • 756 citations

An adaptive coding model of neural function in prefrontal cortex

2001 • 744 citations

Binding of Neuroligins to PSD-95

1997 • 731 citations

EphB Receptors Interact with NMDA Receptors and Regulate Excitatory Synapse Formation

2000 • 702 citations

GABA Itself Promotes the Developmental Switch of Neuronal GABAergic Responses from Excitation to Inhibition

2001 • 693 citations

Axonal Remodeling and Synaptic Differentiation in the Cerebellum Is Regulated by WNT-7a Signaling

2000 • 686 citations

α-Neurexins couple Ca2+ channels to synaptic vesicle exocytosis

2003 • 668 citations

Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors

1990 • 649 citations

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity

2000 • 640 citations

The Dynamics of Dendritic Structure in Developing Hippocampal Slices

1996 • 611 citations

Assembly of presynaptic active zones from cytoplasmic transport packets

2000 • 602 citations

Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming

2002 • 598 citations

Lipid Rafts in the Maintenance of Synapses, Dendritic Spines, and Surface AMPA Receptor Stability

2003 • 570 citations

Maturation of a Central Glutamatergic Synapse

1996 • 551 citations

CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins

1996 • 534 citations

A Developmental Change in NMDA Receptor-Associated Proteins at Hippocampal Synapses

2000 • 521 citations

wishful thinking Encodes a BMP Type II Receptor that Regulates Synaptic Growth in Drosophila

2002 • 520 citations

Structure, development, and plasticity of dendritic spines

1999 • 511 citations

The formation and maturation of synapses in the visual cortex of the rat. II. Quantitative analysis

1983 • 506 citations

Silent Synapses during Development of Thalamocortical Inputs

1997 • 502 citations

Selective acquisition of AMPA receptors over postnatal development suggests a molecular basis for silent synapses

1999 • 496 citations

Semaphorin 7A promotes axon outgrowth through integrins and MAPKs

2003 • 491 citations

Assembly of New Individual Excitatory Synapses

2000 • 490 citations

Cadherin Regulates Dendritic Spine Morphogenesis

2002 • 485 citations

Rapid Induction of Dendritic Spine Morphogenesis by trans-Synaptic EphrinB-EphB Receptor Activation of the Rho-GEF Kalirin

2003 • 466 citations

Importance of the Intracellular Domain of NR2 Subunits for NMDA Receptor Function In Vivo

1998 • 465 citations

Synaptic Clustering of AMPA Receptors by the Extracellular Immediate-Early Gene Product Narp

1999 • 457 citations

The Developing Synapse: Construction and Modulation of Synaptic Structures and Circuits

2002 • 453 citations

Postsynaptic organisation and regulation of excitatory synapses

2000 • 452 citations

Postnatal synaptic potentiation: Delivery of GluR4-containing AMPA receptors by spontaneous activity

2000 • 427 citations

Assembling the Presynaptic Active Zone

2001 • 421 citations

The Drosophila Wnt, Wingless, Provides an Essential Signal for Pre- and Postsynaptic Differentiation

2002 • 416 citations

Ca2+ Oscillations Mediated by the Synergistic Excitatory Actions of GABAA and NMDA Receptors in the Neonatal Hippocampus

1997 • 404 citations

Regulation of morphological postsynaptic silent synapses in developing hippocampal neurons

1999 • 399 citations

Heterogeneity in the Molecular Composition of Excitatory Postsynaptic Sites during Development of Hippocampal Neurons in Culture

1998 • 396 citations

Stabilization of Dendritic Arbor Structure in Vivo by CaMKII

1998 • 381 citations

Increasing Numbers of Synaptic Puncta during Late-Phase LTP

2000 • 373 citations

Emergence of order in visual system development.

1996 • 361 citations

Ligand-Gated Ion Channel Interactions with Cytoskeletal and Signaling Proteins

2000 • 352 citations

Unitary Assembly of Presynaptic Active Zones from Piccolo-Bassoon Transport Vesicles

2003 • 344 citations

Depolarization Drives β-Catenin into Neuronal Spines Promoting Changes in Synaptic Structure and Function

2002 • 335 citations

Morphological analysis of dendritic spine development in primary cultures of hippocampal neurons

1995 • 332 citations

The Drosophila BMP Type II Receptor Wishful Thinking Regulates Neuromuscular Synapse Morphology and Function

2002 • 330 citations

Integrins mediate functional pre- and postsynaptic maturation at a hippocampal synapse

2001 • 326 citations

The Receptor Tyrosine Kinase EphB2 Regulates NMDA-Dependent Synaptic Function

2001 • 309 citations

Kinase-Independent Requirement of EphB2 Receptors in Hippocampal Synaptic Plasticity

2001 • 307 citations

Receptor trafficking and the plasticity of excitatory synapses

2002 • 304 citations

EphB/Syndecan-2 Signaling in Dendritic Spine Morphogenesis

2001 • 303 citations

Induction of dendritic spines by an extracellular domain of AMPA receptor subunit GluR2

2003 • 302 citations

Rapid formation and remodeling of postsynaptic densities in developing dendrites

2001 • 298 citations

Spine Formation and Correlated Assembly of Presynaptic and Postsynaptic Molecules

2001 • 288 citations

The Establishment of GABAergic and Glutamatergic Synapses on CA1 Pyramidal Neurons is Sequential and Correlates with the Development of the Apical Dendrite

1999 • 287 citations

Rapid recruitment of NMDA receptor transport packets to nascent synapses

2002 • 283 citations

Dual Palmitoylation of Psd-95 Mediates Its Vesiculotubular Sorting, Postsynaptic Targeting, and Ion Channel Clustering

2000 • 272 citations

Integrin Subunit Gene Expression Is Regionally Differentiated in Adult Brain

1999 • 245 citations

Regulation of intracellular Cl- levels by Na(+)-dependent Cl- cotransport distinguishes depolarizing from hyperpolarizing GABAA receptor-mediated responses in spinal neurons

1996 • 244 citations

Maturation of rat visual cortex. II. A combined Golgi‐electron microscope study of pyramidal neurons

1981 • 235 citations

Early development of neuronal activity in the primate hippocampus in utero.

2001 • 229 citations

A Developmental Switch in Neurotransmitter Flux Enhances Synaptic Efficacy by Affecting AMPA Receptor Activation

2001 • 226 citations

The integrin family of cell adhesion molecules has multiple functions within the CNS

2002 • 212 citations

Integrin Requirement for Hippocampal Synaptic Plasticity and Spatial Memory

2003 • 202 citations

Early Development of Neuronal Activity in the Primate HippocampusIn Utero

2001 • 199 citations

The Making of Neurexins

1998 • 155 citations

Synaptically Targeted Narp Plays an Essential Role in the Aggregation of AMPA Receptors at Excitatory Synapses in Cultured Spinal Neurons

2002 • 150 citations

Comparison of Hippocampal Dendritic Spines in Culture and in Brain

1998 • 142 citations

Postsynaptically Silent Synapses in Single Neuron Cultures

1998 • 138 citations

Postsynaptic Calcium/Calmodulin-Dependent Protein Kinase II Is Required to Limit Elaboration of Presynaptic and Postsynaptic Neuronal Arbors

1999 • 127 citations

The Dynamics of SAP90/PSD-95 Recruitment to New Synaptic Junctions

2001 • 122 citations

Microtubule binding by CRIPT and its potential role in the synaptic clustering of PSD-95

1999 • 109 citations

Acute versus chronic NMDA receptor blockade and synaptic AMPA receptor delivery

2002 • 97 citations

Presynaptic control of quantal size: kinetic mechanisms and implications for synaptic transmission and plasticity

2003 • 79 citations

Genetic Analysis on the Role of Integrin during Axon Guidance inDrosophila

1998 • 69 citations

Temporal Appearance of the Presynaptic Cytomatrix Protein Bassoon during Synaptogenesis

2000 • 65 citations

Developing corticorubral axons of the cat form synapses on filopodial dendritic protrusions

1992 • 38 citations